17 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
European Lead Factory (EUC²LID)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
Voir le projet
34
Participants partenaires
TERMINÉ
Kinetics for Drug Discovery (K4DD) (K4DD)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
There is mounting evidence that the often ignored kinetic aspects of the interaction between a drug and its target are highly relevant for clinical success. This ignorance may be one of the reasons for the high attrition rates in drug discovery, as it has been analyzed that many recently marketed drugs had indeed improved kinetic profiles. This hindsight knowledge needs to be converted into data-d ...
Voir le projet
21
Participants partenaires
TERMINÉ
Development of improved perennial non-food biomass and bioproduct crops for water stressed environments (WATBIO)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
"The goal of WATBIO is to use the power of next generation sequencing to develop an accelerated route for producing new germplasm with enhanced drought tolerance whilst maintaining biomass productivity and quality in water scarce, marginal environments unsuitable for food crops.This will be achieved for three non-food crops (Populus, Miscanthus and Arundo), suitable for growth on water scarce, mar ...
Voir le projet
23
Participants partenaires
TERMINÉ
Recognising Adverse Drug Reactions (WEB-RADR)
Date du début: 1 sept. 2014, Date de fin: 31 août 2017,
WEB-RADR is a consortium of leading experts in pharmacovigilance from regulatory agencies, research, academia and patient support groups. Together with EFPIA partners our aims will be to set policy & guidance and deliver robust information technology tools to address the potential for the reporting of adverse drug reactions (ADRs) through mobile applications and the recognition of drug safety sign ...
Voir le projet
20
Participants partenaires
TERMINÉ
BeTheCuRE (BTCURE)
Date du début: 1 avr. 2011, Date de fin: 31 mars 2017,
BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
Voir le projet
41
Participants partenaires
TERMINÉ
European Patients' Academy on Therapeutic Innovation (EUPATI)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,
"The proposed project ""European Patients' Academy on Therapeutic Innovation"" (EUPATI) contributes to IMI’s goal of raising patients’ awareness and participation in pharmaceutical R&D. This patient-led academy will provide scientifically reliable, objective, comprehensive information to patients on pharmaceutical R&D. It will increase the capacity of well-informed patients to be effective advocat ...
Voir le projet
33
Participants partenaires
TERMINÉ
Mechanism-Based Integrated Systems for the Prediction of Drug-Induced Liver Injury (MIP-DILI)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,
The current test systems employed by Industry are poorly predictive for Drug induced liver injury (DILI). The ‘MIP-DILI’ project will address this situation by the development of innovative preclinical test systems which are both mechanism-based and of physiological, pharmacological and pathological relevance to DILI in humans. An iterative, tiered approach with respect to test compounds, test sys ...
Voir le projet
29
Participants partenaires
TERMINÉ
Integrating bioinformatics and chemoinformatics approaches for the development of expert systems allowing the in silico prediction of toxicities (ETOX)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2016,
The eTOX consortium proposes to develop innovative methodological strategies and novel software tools to better predict the toxicological profiles of new molecular entities in early stages of the drug development pipeline. This will be achieved by coordinating the efforts of specialists from academia and SMEs in the wide scope of disciplines that are required to move towards a more reliable modell ...
Voir le projet
30
Participants partenaires
TERMINÉ
European Medicines Research Training Network (EMTRAIN)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2016,
EMTRAIN is an essential element for the success of the IMI Education & Training (E&T) Call Topics in Europe (current and future). It will establish a pan-European platform of excellence for education and training covering the whole life-cycle of medicines from basic research through clinical development to pharmaco-vigilance. It will underpin the successful delivery of the current and future IMI-f ...
Voir le projet
32
Participants partenaires
TERMINÉ
Drug Disease Model Resources (DDMORE)
Date du début: 1 mars 2011, Date de fin: 31 août 2016,
Model based-drug development (MBDD) is accepted as a vital approach in understanding patient risk/benefit and attrition. At the core of MBDD lies Modelling and Simulation (M&S), a technology providing the basis for informed, quantitative decision-making.M&S facilitates the continuous integration of available information related to a drug or disease into constantly-evolving mathematical models capa ...
Voir le projet
28
Participants partenaires
TERMINÉ
European programme in Pharmacovigilance and Pharmacoepidemiology (EU2P)
Date du début: 1 sept. 2009, Date de fin: 30 juin 2016,
The Eu2P training network in Pharmacovigilance and Pharmacoepidemiology will meet the needs of industry,regulatory authorities and academia at the European level. It will give access to a harmonised training programme that gathers complementary specialized and eminent European partners. The Eu2P consortium consists of course providers with aproven record including the University of Bordeaux (Eu2P ...
Voir le projet
24
Participants partenaires
TERMINÉ
Prediction of cognitive properties of new drug candidates for neurodegenerative diseases in the early clinical development (PHARMA-COG)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2015,
PHARMA-COG aims to develop a new integrated model to accelerate the development of drug cindidates for MS, PKD and AD. The innovation relies on a 'multidimensional matrix' approach, integrating all available and renewed inputs (biomarkers/animal, human models/physiological and pharmcological challenges, Phase 0/1/1b to reduce the attrition rate, to allow an early and pertinent GO/NOGO decision bef ...
Voir le projet
38
Participants partenaires
TERMINÉ
Understanding chronic pain and improving its treatment (EUROPAIN)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2015,
We will establish an international team of leading researchers and clinicians (EuroPain) to undertake multidisciplinary translational research which will: 1) increase the understanding of chronic pain mechanisms; 2)facilitate the development of novel analgesic drugs; and 3) improve the treatment of chronic pain patients.Nineteen researchers drawn from the London Pain Consortium, the Danish Pain Re ...
Voir le projet
29
Participants partenaires
TERMINÉ
Pharmacoepidemiolocal Research on Outcomes of Therapeutics by a European ConsorTium (PROTECT)
Date du début: 1 sept. 2009, Date de fin: 30 avr. 2015,
Recent pharmacovigilance (PV) issues have led to questions regarding the ability of the current PV system to meet the global needs. Controversies around the assessment of spontaneous reports and conflicting results from pharmacoepidemiology studies may lead to delay in, or inappropriate, regulatory decisions. The PROTECT consortium, consisting of 20 core partners lead by the European Medicines Age ...
Voir le projet
36
Participants partenaires
TERMINÉ
Pharmaceutical Medicine Training Programme (PHARMATRAIN)
Date du début: 1 mai 2009, Date de fin: 30 avr. 2014,
"The proposed Pharmaceutical Medicine Training Programme provides a comprehensive solution for the complex needs of integrated drug development for all professionals involved, incl. physicians, pharmaceutical scientists,biologists, biometricians, health economists, and safety and regulatory scientists from universities, regulatory agencies, large, middle-sized and small pharmaceutical enterprises, ...
Voir le projet
52
Participants partenaires
TERMINÉ
INtegrated HEart Research In TrANslational genetics of dilated Cardiomyopathies in Europe (INHERITANCE)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2013,
"Inherited dilated cardiomyopathies (DCM) are monogenic disorders caused by mutations in more than 30 genes, characterised by substantial phenotype heterogeneity. DCM affects 1:2.500 individuals and is the major cause of heart transplantation and death for non-ischaemic heart failure in adolescents and young adults. Currently, less than 1% of patients with familial DCM are genotyped in Europe. The ...
Voir le projet
11
Participants partenaires
TERMINÉ
Projektet ska skapa en stark kompetensregion inom crossmedia design – som drivs av en innovationsmiljö bestående av representanter från näringsliv, universitet och offentlig sektor. De ska samla forskningsresurser med koppling till mediadesign från deltagande parters universitet, skapa ett långsiktigt forskningsprogram inriktat på att fylla framtida behov inom mediasektorn och ska långsiktigt till ...
Voir le projet