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17 projets européens trouvés

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 TERMINÉ 

Distributed Infrastructure for EXPErimentation in Ecosystem Research (EXPEER)

Date du début: 1 déc. 2010, Date de fin: 31 mai 2015,

EXPEER will bring together, major observational, experimental, analytical and modelling facilities in ecosystem science in Europe. By uniting these highly instrumented ecosystem research facilities under the same umbrella and with a common vision, EXPEER will form a key contribution to structuring and improving the European Research Area (ERA) within terrestrial ecosystem research.EXPEER builds ...
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 41

 TERMINÉ 

Exploitation of Our Intestinal Microbiota (MICROBESINSIDE)

Date du début: 1 juin 2010, Date de fin: 31 mai 2015,

Our intestinal tract is colonized by a myriad of microbes that exceed our body cells in number and coding capacity and have important metabolic and signaling functions. Analysis of the diversity of these microbes inside revealed more than 1000 species, some of which have developed intimate interactions that are operating at the mucus interface separating the intestinal and microbial cells. Notably ...
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 2

 TERMINÉ 

"Neutralizing antibodies against botulinum toxins A,B,E" (ANTIBOTABE)

Date du début: 1 sept. 2010, Date de fin: 28 févr. 2015,

"Botulinum neurotoxins (BoNTs), the most toxic substances known, are susceptible for use as bioweapons (listed as class A agents by CDC). Currently licensed animal derived antibodies or F(ab’)2 preparations, are at a high risk of inducing adverse effects and their privately-owned stockpiles are limited. In this project, we will target the most lethal types of BoNTs: A (subtypes A1 and A2), B (B1 a ...
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 11

 TERMINÉ 

Peptide-based Nanoparticles as Ocular Drug Delivery Vehicles (PANOPTES)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,

"This project will develop methodology for the manufacture of novel peptide-based nanoparticles and nanocapsules to satisfy an unmet clinical need: sustained drug delivery to the posterior segment of the eye. The proposed consortium brings together internationally leading groups in self-assembling polypeptide nanoparticle and nanocapsule preparation by chemical (Durham) and genetic (Nijmegen) appr ...
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 6

 TERMINÉ 
Our capacity to effectively sustain biodiversity across spatial and temporal scales is an essential component of European environmental sustainability. Anthropogenic and environmental pressures on biodiversity act differently at different scales. Consequently, effective conservation responses to these threats must explicitly consider the scale at which effects occur, and therefore it is crucial th ...
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 31

 TERMINÉ 
"Low input farming occurs under non-SPF (specific pathogen free) conditions. The European ban on in-feed antibiotics exposes the piglets to a higher microbial environmental pressure. The postnatal priming of piglets with a diverse microbiota may affect the development of the piglet’s host-defense and gut functionality. By reversal, the piglets developing host-defense may affect the development of ...
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 13

 TERMINÉ 
The NEMO project provides novel efficient enzymes and microbes for 2nd generation bioethanol production. It generates through metabolic engineering and mutagenesis & screening approaches robust yeast strains that have a broad substrate range and can (co-)ferment C6 and C5 sugars to ethanol with high productivity (rate and yield), and that are significantly more stress tolerant, i.e. inhibitor, eth ...
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 21

 TERMINÉ 
"The production of fine and industrial chemicals and bioactive compounds based on renewable, naturally occurring raw materials has become an exciting research topic, but so far only few studies concern side products of the forest industry. We will focus on bark and on peat. Bark is a high-volume waste product, currently largely unutilised as a raw material. Northern Europe and Russia have abundant ...
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 9

 TERMINÉ 
"MOLPARK aims to define the basic cellular and molecular mechanisms underlying the generation, differentiation, survival and connectivity of nigrostriatal dopaminergic neurons and translate this knowledge into radically new therapeutic strategies for Parkinson's disease (PD). MOLPARK brings together two industrial partners and 6 world-renowned academic groups with a uniquely advantageous knowledge ...
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 7

 TERMINÉ 
"Lignocellulosic bioethanol has the potential of contributing to a sustainable and secure European energy supply for the transport sector. European research and industry is presently among the forerunners in developing lignocellulosic bioethanol. Although a number of technical breakthroughs have been achieved during the last decade, some key technical issues especially concerning the hydrolysis an ...
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 9

 TERMINÉ 
"At present more than 5 million people in the EU suffer from dementia and other neurodegenerative diseases and that number will grow as the average age of the population continues to increase. The efficacy of current medicines is limited and new therapeutic targets are sorely needed. Several independent lines of evidence have established an important role of prolyl oligopeptidase (PREP) in brain f ...
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 12

 TERMINÉ 
"The aim of the proposed DISCO project is to develop more efficient and therefore more cost-effective cellulosic and hemicellulosic enzyme tools for the enhanced hydrolysis of pre-treated lignocellulosic biomass in simultaneous saccharification and fermentation (SSF) conditions for bioethanol production. The focus will be on enzymes having increased catalytic activity on various types of relevant ...
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 12

 TERMINÉ 

EUROPEAN DRUG INITIATIVE ON CHANNELS AND TRANSPORTERS (EDICT)

Date du début: 1 févr. 2008, Date de fin: 30 juin 2012,

"The European Drug Initiative on Channels and Transporters, EDICT, allies for the first time, partners with world-class expertise in both the structural and functional characterisation of membrane channels and transporters. State-of-the-art facilities and personnel for X-ray crystallography, Electron Microscopy and Nuclear Magnetic Resonance and the latest throughput technology, will provide infra ...
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 28

 TERMINÉ 
"European soil biodiversity is pivotal for delivering food, fiber and biofuels and carbon storage. However, the demand is greater than the amount of soil available, as production of biofuels competes with areas for food production and nature. Moreover, intensified land use reduces soil biodiversity and the resulting ecosystem services. SOILSERVICE will value soil biodiversity through the impact on ...
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 11

 TERMINÉ 

Judgement and Knowledge in Fisheries including Stakeholders (JAKFISH)

Date du début: 1 mai 2008, Date de fin: 31 oct. 2011,

"The project will investigate how different actors in the marine sector, including fisheries, make use of scientific knowledge, how the roles that scientists play help formulate policies and how governance approaches can be developed which enable policy decisions to address uncertainty and complexity based on research and with the participation of stakeholders. The project will collect and build o ...
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 10

 TERMINÉ 
"The concept of VITAL is the integrated monitoring and control of contamination of the European food supply chain by pathogenic viruses. VITAL will use advanced methods for virus detection throughout selected food supply chains from farm to market, to gather data on virus contamination of food and environmental sources suitable for quantitative viral risk assessment. Supply chains will be monitore ...
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 13

 TERMINÉ 

Trimeric Bacterial Autotransporters (TrimBAt)

Date du début: 1 juil. 2008, Date de fin: 30 juin 2010,

Bacterial adhesins play a crucial role in pathogen-host interactions, initiating infections by adhesion to the extracellular matrix and to cell surface proteins prior to invasion. A family of non-fimbrial adhesins, the trimeric autotransporter adhesins (TAAs), has recently been described in gram-negative pathogens. The common biological role of all these TAAs is to mediate the interaction of patho ...
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 1