4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Determining how invasive S. Typhimurium infects human cells by transposon-insertion sequencing (DISTINCT)
Date du début: 1 sept. 2014, Date de fin: 31 août 2016,
"Salmonella enterica serovar Typhimurium infects a wide range of animal hosts and normally causes a self-limiting gastroenteritis in humans. However, new variants of this serovar known as ST313 have emerged as important pathogens in sub-Saharan Africa, causing an invasive disease in susceptible HIV+ or malarial individuals. Genome sequencing showed that the ST313 isolate D23580 is closely related ...
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TERMINÉ
Comparative genomics and gene expression profile of sexual and parthenogenetic Ischnura hastata (Insecta, Odonata) (ODOGEN)
Date du début: 1 mai 2014, Date de fin: 30 avr. 2016,
Understanding the evolutionary consequences of sexual and asexual reproduction remains one of the most hotly-debated topics in evolutionary biology, with contemporary genomics technology now offering the prospect of shedding new light on this issue. Despite a lower intrinsic population growth rate, because sexual species maintain greater genetic diversity they should have greater prospects of adap ...
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TERMINÉ
Fish Indicatiors of Stress and Health (FISH): Validating the use of embryos and yolk sac larval zebrafish as a model for the study of nociception and veterinary drug testing (FISH)
Date du début: 14 avr. 2014, Date de fin: 13 avr. 2016,
The zebrafish (ZF) is now a widely accepted vertebrate model for research in genetics, neuroscience and development due to its sheer experimental convenience and also its gene, developmental and functional homologies with mammals. ZF are also exploited as a novel model in nociceptive or pain research in a number of laboratories. We are already assessing behavioural and physiological responses in a ...
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TERMINÉ
Nanoparticle probes for photoacoustic tracking of stem cell (NANOSTEMCELLTRACKING)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2016,
Better understanding on stem cell tracking is required before regenerative medicines therapies (RMTs) can be used. However, there is not a single molecular imaging technology capable of providing the breadth of information required. For instance, while MRI offers excellent spatial resolution, sensitivity is low, whereas for SPECT/PET, the converse is true.In this context, the combination of nanote ...
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