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Plus de 40 projets européens trouvés

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 TERMINÉ 

Clinical proof of concept through a randomised phase II study: a combination of immunotherapy and stereotactic ablative radiotherapy as a curative treatment for limited metastatic lung cancer (IMMUNOSABR)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2022,

IMMUNOSABR is geared towards opening up a new paradigm in treating metastatic cancer by obtaining clinical proof of concept for a novel bi-modal curative treatment strategy. High precision stereotactic ablative radiotherapy (SABR) is combined with immunotherapy to form a powerful synergistic anti-tumour strategy. The approach relies on the direct cytotoxic effect of SABR, the abscopal effect of ra ...
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 17

 TERMINÉ 

Bright Future for Black Vulture in Bulgaria (Vultures back to LIFE)

Date du début: 16 juil. 2015, Date de fin: 15 juil. 2022,

Background The most serious problem for vultures in Bulgaria today is the critically low number of populations and their isolation. In spite of two decades of conservation efforts, the WWF Greece Dadia project showed that the number of breeding pairs is not increasing and remains around 20 pairs. Another threat is unsuitable livestock breeding practices r ...
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 5

 TERMINÉ 

Genomics of Chromosome Architecture and Dynamics in Single Cells (GoCADiSC)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2022,

"The spatial architecture of mammalian interphase chromosomes, each consisting of tens of megabases of DNA, poses an intriguing topological problem and is relevant for various nuclear functions. A major challenge is that chromosome architecture exhibits substantial stochastic cell-to-cell variation. To unravel the principles of chromosome organization, new single-cell genome-wide approaches that c ...
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 1

 TERMINÉ 

Understanding information for legal protection of people against information-induced harms (INFO-LEG)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2022,

Information can harm people. Think of being denied mortgage or insurance based on your grocery shopping or online surfing profile. But what exactly is it in information that is harmful, and how can people be protected? The current legal answer is that protection (data protection principles, rights and obligations) is granted when a) there is information b) about or potentially affecting a person c ...
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 1

 TERMINÉ 

Healthy minds from 0-100 years: Optimising the use of European brain imaging cohorts (Lifebrain)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Our main objective is to identify determinants of brain, cognitive and mental health at different stages of life. By integration, harmonisation and enrichment of major European neuroimaging studies of age differences and changes, we will obtain an unparalleled database of fine-grained brain, cognitive and mental health measures of more than 6.000 individuals. Longitudinal brain imaging, genetic an ...
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 16

 TERMINÉ 

Optimizing a deployable high efficacy malaria vaccine (OptiMalVax)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

A highly effective malaria vaccine against Plasmodium falciparum should help prevent half a million deaths from malaria each year. New vaccine technologies and antigen discovery approaches now make accelerated design and development of a highly effective multi-antigen multi-stage subunit vaccine feasible. Leading malariologists, vaccine researchers and product developers will here collaborate in ...
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 17

 TERMINÉ 

Early-life stressors and LifeCycle health (LIFECYCLE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Early life is an important window of opportunity to improve health across the full lifecycle. European pregnancy and child cohort studies together offer an unique opportunity to identify a wide range of early life stressors linked with individual biological, developmental and health trajectory variations, and to the onset and evolution of non-communicable diseases. LIFECYCLE will establish the Eur ...
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 19

 TERMINÉ 

Fostering responsive mental health systems in the Syrian refugee crisis (STRENGTHS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

STRENGTHS aims to provide effective community-based health care implementation strategies to scale-up the delivery and uptake of effective mental health interventions in different country contexts. The current refugee crisis across Europe and the Middle East effects both individual refugees’ psychological well-being, as they face extreme stressors in their flight from their home country, but also ...
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 15

 TERMINÉ 

European Sudden Cardiac Arrest network: towards Prevention, Education and NEw Treatment (ESCAPE-NET)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Sudden cardiac arrest (SCA) causes ~20% of all deaths in Europe. SCA is lethal within minutes if left untreated and survival rates are presently only 5-20%. Therefore, there is a large medical need to improve SCA prevention and treatment. Designing effective individualized prevention and treatment strategies requires knowledge on genetic and environmental risk factors. So far, these efforts have b ...
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 17

 TERMINÉ 

LIFE URBAN-ADAPT: demonstrating urban climate adaptation and resilience in inner city Rotterdam (LIFE URBAN-ADAPT)

Date du début: 16 juil. 2015, Date de fin: 31 déc. 2021,

Background Climate change is a global development issue, with the potential to cause serious problems for the urban environment: 1. Increased flood risk because of increased precipitation and rising water levels; 2. Increased temperatures resulting from the urban heat island effect; and 3. Deterioration of native flora and fauna on land and in water. ...
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 3

 TERMINÉ 

Analysing coherence in law through legal scholarship (CLLS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Coherence of law is created in the writings of legal scholars who systematize rules and principles of law. Their pursuit of coherence is vital for the effectiveness of legal systems. However, coherence of law has almost not been analysed in a systematic, empirical way. The project will therefore develop a methodology that will address coherence across forms (‘sources’) of law (legislation, legal s ...
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 1

 TERMINÉ 

Support to Future CROR and UHBR Propulsion System Maturation (PropMat)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2021,

In the framework of the Large Passenger Aircraft ITD of Clean Sky 2, the industrial partners Airbus & Safran will push the CROR and UHBR low fuel burn propulsion concepts to TRL6 with a flight test demonstration program on the A340-300 MSN001 aircraft. The activities proposed in this document will make a valuable contribution to this program. The activities comprise: CROR&UHBR numerical aero-acous ...
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 1

 TERMINÉ 

Combatting Bacterial Resistance in Europe - Molecules against Gram Negative Infections (COMBACTE-MAGNET)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2021,

Antimicrobial resistance (AMR) is a major global public health threat, and most troublesome is the rapid emergence and dissemination of multidrug resistant (MDR) Enterobacteriaceae, Acinetobacter species and Pseudomonas aeruginosa. There is an unmet medical need to prevent P. aeruginosa infection in critically ill patients and to develop new antibiotics for infections caused by Gram-negative bacte ...
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 44

 TERMINÉ 

Goal-directed eye-head coordination in dynamic multisensory environments (ORIENT)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Rapid object identification is crucial for survival of all organisms, but poses daunting challenges if many stimuli compete for attention, and multiple sensory and motor systems are involved in the processing, programming and generating of an eye-head gaze-orienting response to a selected goal. How do normal and sensory-impaired brains decide which signals to integrate (“goal”), or suppress (“dis ...
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 1

 TERMINÉ 

Neural decisions under uncertainty (NOISYDECISIONS)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2021,

Virtually anything we sense, think and do is uncertain. For instance, when driving a car, you often need to determine how close you are to the car in front of you. It is near impossible to estimate this distance with absolute certainty – but it is possible to guess and even to estimate the uncertainty associated with that guess. Accordingly, we reduce speed when driving at night, because we realiz ...
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 1

 TERMINÉ 

The Flagship ERA-NET (FLAG-ERA II)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2021,

FLAG-ERA, the Flagship ERA-NET, gathers national and regional funding organisation with the goal of supporting, together with the European Commission, the FET Flagship initiatives and more generally the FET Flagship programme. Most funding organisations in Europe participate, either directly or as associated members. FLAG-ERA contributes to the construction of the two Flagship initiatives on Graph ...
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 23

 TERMINÉ 

Restoration of connections between the Alpine and Pyrenean populations of bearded vulture (Gypaetus barbatus) (LIFE GYPCONNECT)

Date du début: 1 sept. 2015, Date de fin: 30 nov. 2021,

Background The conservation status of the bearded vulture (Gypaetus barbatus) is listed as vulnerable on the European IUCN Red List and endangered in France. Before vulture reintroductions started, the Alps represented a huge barrier separating the Pyreneo-Iberian populations and those of the Balkans. To bridge the distance between the populations of the ...
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 9

 TERMINÉ 

THAWing permafrost: the fate of Soil Organic Matter in the aquatic Environment (THAWSOME)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2021,

As the Arctic permafrost region warms, its large organic carbon (OC) pool becomes vulnerable to decomposition. This generates greenhouse gases (GHG) that in turn fuel increased surface warming: the permafrost carbon feedback. Higher temperatures will jump-start the coupling between the carbon and hydrological cycle, allowing for the introduction of previously frozen OC pools in aquatic systems. Th ...
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 1

 TERMINÉ 

ERA-NET ON NANOMEDICINE (EuroNanoMed III)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2021,

Nanomedicine is the application of nanotechnology to medicine and healthcare. The field takes advantage of the physical, chemical and biological properties of materials at the nanometer scale to be used for a better understanding of the biological mechanisms of diseases at the molecular level, leading to new targets for earlier and more precise diagnostics and therapeutics. Nanomedicine, rated amo ...
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 25

 TERMINÉ 

QuantERA ERA-NET Cofund in Quantum Technologies (QuantERA)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2021,

QuantERA ERA-NET Cofund in Quantum TechnologiesQuantum Technologies (QT) has become a new and fast developing area of research initiated by a realisation that quantum physics opens up radically new modes of quantum information processing and communication. European researchers have been at the forefront of these developments delivering many groundbreaking scientific results and advancing technolog ...
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 31

 TERMINÉ 

CHROMIUM

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,

Why the Universe is void of anti-matter is one of the remaining Big Questions in Science.One explanation is provided within the Standard Model by violation of Charge Parity (CP) symmetry, producing differences between the behavior of particles and their anti-particles.CP violation in the neutrino sector could allow a mechanism by which the matter-anti matter asymmetry arose.The objective of this p ...
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 2

 TERMINÉ 

Proton conduction in structured water (PROWAT)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,

In recent years water near surfaces and solutes has been observed to be differently structured and to show slower reorientation and hydrogen-bond dynamics than in bulk. Aqueous proton transfer is a process that strongly relies on the structure and dynamics of the hydrogen-bond network of liquid water and that often occurs near surfaces. Examples are thylakoid and mitochondrial membranes and the na ...
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 1

 TERMINÉ 

Microbial lipids: The three domain ‘lipid divide’ revisited (MICROLIPIDS)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,

Tremendous progress has been made in the last decade in the genetic characterization of microorganisms, both in culture and in the environment. However, our knowledge of microbial membrane lipids, essential building blocks of the cell, has only marginally improved. This is remarkable since there exists a dichotomy in the distribution of lipids between the three Domains of Life. Diacyl glycerols ba ...
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 1

 TERMINÉ 

ERA-NET Cofund Electric Mobility Europe (EMEurope)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,

In collaboration with the European Commission and the European Green Vehicles Initiative Association, European countries and regions will set-up an ERA-NET Cofund to further promote electric mobility in Europe. Electric Mobility Europe builds on the experiences, networks and results of Electromobility+ and is designed to take transnational e-mobility research and policy exchange to the next level. ...
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 20

 TERMINÉ 

ERA-NET ON ADVANCED MANUFACTURING TECHNOLOGIES (MANUNET III)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,

Europe is facing major economic challenges that require an ambitious economic policy for the 21st century. The EU has set out its vision for Europe's social market economy in the Europe 2020 strategy, which aims at confronting our structural weaknesses through progress in three mutually reinforcing priorities:• smart growth, based on knowledge and innovation,• sustainable growth, promoting a more ...
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 25

 TERMINÉ 

NEURASMUS : A EUROPEAN MASTER IN NEUROSCIENCE : ADVANCED COURSE AND RESEARCH TRAINING

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

With brain diseases responsible for 35% of Europe’s disease burden, neuroscience research is pivotal in fighting the challenges faced by our health systems. Meanwhile, pharmaceuticals across Europe report a shortage of neuroscientists properly trained in experimental methodologies and the latest techniques used in clinical and industrial research. Neurasmus is a two-year joint Master Programme in ...
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 5

 TERMINÉ 

Middlebrow Enlightenment: Disseminating Ideas, Authors, and Texts in 18th-century Europe (MEDIATE)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

Intellectual history has long focused on a small number of authors and conceptual frameworks in studying societal change during the Enlightenment. Historians of the book have similarly restricted their vision, tending to privilege radical, subversive or forbidden texts. Yet ever since Daniel Mornet launched the history of the book approach a century ago, historians have recognized that it was auth ...
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 1

 TERMINÉ 

The Proton Size Puzzle: Testing QED at Extreme Wavelengths (QED-PROTONSIZE)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

A key component of the Standard Model is Quantum Electrodynamics (QED). QED explains e.g. the anomalous magnetic moment of the electron and small energy shifts in the energy structure of atoms and molecules due to vacuum fluctuations. After decades of precision measurements, especially laser spectroscopy in atomic hydrogen, QED is considered the most successful and best-tested theory in physics. H ...
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 1

 TERMINÉ 

Stress Resilience and Network-Feedback Training (STRESNET)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

Acute stress has a profound impact on cognitive functioning: it raises alertness for threat, yet it impairs our ability to think clearly. Repeated exposure to stressors is furthermore a critical transdiagnostic factor in etiology, relapse, and chronification in almost all psychiatric disorders. We know from animal work at the cellular level how stressors trigger a neurochemical cascade that alters ...
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 1

 TERMINÉ 

Political Apologies across Cultures (APOLOGY)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

In the past decades, there has been a considerable rise in the number of apologies offered by states for injustices and human rights violations. Among transitional justice scholars, there is significant debate about how useful such apologies are. Whereas some have applauded these gestures as an important step in peacemaking processes, others have argued that they may not fit in all cultures and ma ...
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 1

 TERMINÉ 

Scientific Top Training in Antimicrobial Research (AIMMS STAR-PLUS)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

The Amsterdam Institute for Molecules, Medicines and Systems (AIMMS, www.aimms.vu.nl) offers an innovative selection procedure for international Top Master's Students to train a new generation of top scientists who can contribute to solving the problem of bacterial, viral and parasitic diseases.A multitude of microbes, and their resistance in particular, threaten the health of European citizens an ...
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 1

 TERMINÉ 

Video games for the prevention of depression and anxiety: A 21st century approach to emotional and mental health in adolescents (GEMH)

Date du début: 1 août 2016, Date de fin: 31 juil. 2021,

Depression and anxiety are the most frequently diagnosed mental health problems, leading to devastating long-term outcomes that affect a huge proportion of adolescents across the globe. Effective prevention programs are urgently needed; however, even our most advanced programs often lead to disappointing outcomes. Video games promise a groundbreaking, 21st century innovation: games provide learnin ...
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 1

 TERMINÉ 

Participatory Urban Governance between Democracy and Clientelism: Brokers and (In)formal Politics (BROKERS)

Date du début: 1 août 2016, Date de fin: 31 juil. 2021,

The emergence of participatory governance has resulted in the delegation of governmental responsibilities to citizens. Individuals position themselves as voluntary mediators, or brokers, between the government and their fellow citizens. This research asks: what are the roles of such brokers in participatory urban governance, and how do they influence democratic governance? This study will investig ...
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 1

 TERMINÉ 

Conservation of Black and Griffon vultures in the cross-border Rhodopes mountains (LIFE RE-Vultures)

Date du début: 1 janv. 2016, Date de fin: 30 juin 2021,

Background European black vultures (Aegypius monachus)and griffon vultures (Gyps fulvus) are considered as umbrella species whose conservation will also substantially benefit other raptor species sharing the main diet of carrion as well as breeding and foraging habitats. These species are also an indicator of healthy, intact, natural habitats. The conserv ...
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 6

 TERMINÉ 

Adaptation to extreme rainfall; demonstration of FHVI to prevent damage by urban pluvial flooding (LIFE AERFIT)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,

Background Climate change scenarios predict more frequent and larger extremes in rainfall. Already, cities in the EU face damage from pluvial flooding. Damages will increase due to climate change and continuing urbanisation. Urban pluvial flooding is a major problem that urgently requires effective, sustainable and cost-effective solutions. Putten regul ...
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 5

 TERMINÉ 

HYDROGEN MEETING FUTURE NEEDS OF LOW CARBON MANUFACTURING VALUE CHAINS (H2Future)

Date du début: 1 janv. 2017, Date de fin: 30 juin 2021,

Under the coordination of VERBUND, VOESTALPINE, a steel manufacturer, and SIEMENS, a PEM electrolyser manufacturer, propose a 26 month demonstration of the 6MW electrolysis power plant installed at the VOESTALPINE LINZ plant (Austria). After pilot plant commissioning, the electrolyser is prequalified with the support of APG, the transmission operator of Austria, in order to provide grid-balancing ...
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 6

 TERMINÉ 

Marine Renewable Infrastructure Network for Enhancing Technologies 2 (MARINET2)

Date du début: 1 janv. 2017, Date de fin: 30 juin 2021,

Integrating activities planned under MaRINET 2 build upon the achievements of the advanced community created in MaRINET FP7. MaRINET 2 will ensure the continued integration and enhancement of all leading European research infrastructure and facilities specialising in research, development and testing of offshore renewable energy systems including electrical sub systems and grid integration through ...
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 39

 TERMINÉ 

Scanning Electron Optical Nanoscopy (SCEON)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,

Novel developments in optical technology increasingly depend on control of light at the nanoscale. To study light at this small length scale it is essential to employ techniques that can excite and image light at the nanoscale. In recent years, my group has explored cathodoluminescence (CL) spectroscopy for this purpose. Based on the exciting potential of this technique, I propose to design and co ...
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 1

 TERMINÉ 

CHECKPOINTS IN CHECK: Novel Chemical Toolbox for Local Cancer Immunotherapy (CHEMCHECK)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,

Cancer evades the immune system by generating an immunosuppressive tumour-microenvironment through various mechanisms to enable unhampered growth. Recent breakthroughs in blocking one of these mechanisms – the so called ‘immune checkpoints’ – put cancer immunotherapy back in the spotlights. Although promising, clinical benefits of these checkpoint inhibitors as single treatment has been limited to ...
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 1

 TERMINÉ 

The Human Behavioral Immune System: Consequences for Health and Innovation (HBIS)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,

Modern innovations such as soap, condoms, and indoor plumbing have allowed billions of people to reduce their contact with viruses and bacteria and, as a result, dramatically increase length and quality of life. But how did members of the genus homo avoid pathogens for the two million years that preceded these technological innovations and, more broadly, discoveries that infectious disease is caus ...
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 1