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TERMINÉ
NANOCARRIERS FOR THE DELIVERY OF ANTIMICROBIAL AGENTS TO FIGHT RESISTANCE MECHANISMS (CycloN Hit)
Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,
The worldwide spread of antibiotic-resistant microorganisms can be viewed as an ecological consequence of the systematic use of antimicrobial agents. Resistant bacteria prevail in healthcare environments where antibiotic selective pressure is intensive. Novel therapeutic approaches are urgently required to deliver the well-documented existing drugs in an optimized fashion to: i) protect them towar ...
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TERMINÉ
Biological Foundation for the Safety Classification of Engineered Nanomaterials (ENM): Systems Biology Approaches to Understand Interactions of ENM with Living Organisms and the Environment (NANOSOLUTIONS)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,
The main objective of this research proposal is to identify and elaborate those characteristics of ENM that determine their biological hazard potential. This potential includes the ability of ENM to induce damage at the cellular, tissue, or organism levels by interacting with cellular structures leading to impairment of key cellular functions. These adverse effects may be mediated by ENM-induced a ...
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