Date du début: 1 oct. 2013,
Date de fin: 30 sept. 2018,
HeCaToS aims at developing integrative in silico tools for predicting human liver and heart toxicity. The objective is to develop an integrated modeling framework, by combining advances in computational chemistry and systems toxicology, for modelling toxic perturbations in liver and heart across multiple scales. This framework will include vertical integrations of representations from drug(metabol ...
Date du début: 1 nov. 2012,
Date de fin: 30 avr. 2017,
This project aims to predict individual disease risk related to the environment, by characterizing the external and internal exposome for common exposures (air and drinking water contaminants) during critical periods of life, including in utero. A large amount of health data is now available from longitudinal cohorts in both children and adults, with detailed information on risk factors, confounde ...
Date du début: 1 janv. 2011,
Date de fin: 31 déc. 2015,
"Assessment of repeated dose toxicity is a standard requirement in human safety evaluation and relies on animal testing as no alternatives are currently accepted for regulatory purposes. An integrated research strategy for the replacement of animal tests needs to comprise the development of biomarkers of long-term toxicity in human target cells. To this aim, the DETECTIVE project will set up a scr ...
Date du début: 1 déc. 2012,
Date de fin: 30 nov. 2015,
Trend analyses indicate that the consumption of meat products in most EU countries is stagnating, with the exception of the market segment ‘light and healthy’. However, consumer perception is increasingly influenced by messages in the media that consumption of nitrite preserved meat products contributes to human cancer risk. Therefore, the aim of the PHYTOME project is to develop new meat processi ...
Date du début: 1 sept. 2012,
Date de fin: 31 déc. 2014,
Over the last 10 years, significant investments have been made in both the European Union and the USA for developing scientific data infrastructures to support the work of research communities, and in improving shared access to data. On both sides of the Atlantic, there is a shared understanding that solutions must be global and that the development of an integrated and interoperable data domain c ...
Date du début: 1 mars 2009,
Date de fin: 28 févr. 2013,
This project concerns the first large-scale application of the full range of –omics technologies in a population study aiming at a) the discovery and validation of novel biomarkers predictive of increased risks of a number of chronic diseases, b) the exploration of the association of such biomarkers with environmental exposures, including high-priority pollutants and emerging exposures, and c) the ...
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