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 TERMINÉ 
We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape ...
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 30

 TERMINÉ 

Intelligent Assessment of Pharmaceutical in the Environment (IPIE)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Active pharmaceutical ingredients (APIs) can be released to the natural environment during the manufacturing process, following use by patients or when unused medicines are disposed of. As APIs are biologically active compounds concerns have been raised about the potential effects of APIs in the environment on human and environmental health. Over the past 15 years, a substantial amount of work has ...
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 29

 TERMINÉ 

Dynamics-aerosol-chemistry-cloud interactions in West Africa (DACCIWA)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

"Massive economic and population growth and urbanisation are expected to lead to a tripling of anthropogenic emissions in southern West Africa (SWA) between 2000 and 2030, the impacts of which on human health, ecosystems, food security and the regional climate are largely unknown. An assessment of these impacts is complicated by (a) a superposition with effects of global climate change, (b) the st ...
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 17

 TERMINÉ 
StratoClim will produce more reliable projections of climate change and stratospheric ozone by a better understanding and improved representation of key processes in the Upper Troposphere and Stratosphere (UTS). This will be achieved by an integrated approach bridging observations from dedicated field activities, process modelling on all scales, and global modelling with a suite of chemistry clima ...
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 30

 TERMINÉ 

Developing skills in the field of integrated energy planning in Med Landscapes

Date du début: 15 oct. 2015, Date de fin: 14 oct. 2018,

The ENEPLAN project was conceived to address the lack of interdisciplinary approaches in higher education on energy planning and RES development in Mediterranean areas, by increasing the capacities of future professionals through innovative ICT-based educational approaches, able to integrate different disciplines (spatial planning, environment, engineering, landscape) and foster collaboration with ...
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 18

 TERMINÉ 
Although vaccination is the cornerstone of prophylaxis, current vaccines provide only moderate protection. Most employ inactivated or protein-based, including multimeric antigen, vaccines requiring annual updating. Their limited antigen loads provide limited capacity for inducing robust immune defences, without assurance that both humoral and cell mediated (CMI) responses, as well as durable immun ...
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 11

 TERMINÉ 

Personalised Prognostic Tools for Early Psychosis Management (PRONIA)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

Affective and non-affective psychoses have a major negative impact on human society. They account for 6.3% of the global burden of disease and cost €207 billion per year in Europe alone, making them the most expensive brain-related disorders and even more expensive than cardiovascular diseases. This socioeconomic burden is largely caused by two core disease features: onset in adolescence and early ...
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 13

 TERMINÉ 
DESIRE will focus on epileptogenic developmental disorders EDD, i.e. early onset epilepsies whose origin is closely related to developmental brain processes. A major cause of EDD are malformations of cortical development (MCD), either macroscopic or subtle. EDD are often manifested as epileptic encephalopathies (EE), i.e. conditions in which epileptic activity itself may contribute to severe cogni ...
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 29

 TERMINÉ 
"The aim of SYBIL is to carry out extensive functional validation of the genetic determinants of rare and common skeletal diseases and the age related factors contributing to these painful conditions. To achieve this goal SYBIL will gather complementary translational and transnational scientists, systems biologists, disease modellers, leading SMEs and industrialists that will perform in-depth char ...
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 19

 TERMINÉ 
In clinical interventions, skill transfer from therapist to children with autism spectrum disorders (ASD) benefits from the inclusion of expressive artefacts such as puppets and animated characters. Well-designed robotic agents have proven to be particularly effective and are becoming an increasingly important tool for mediating between therapists and ASD children in robot-assisted therapy (RAT). ...
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 7

 TERMINÉ 
Over 2 billion people worldwide have different types, degrees, or combinations of disability, literacy, digital literacy or aging related barriers that impede or prevent use of ICT. Not long ago you could live without access to ICT quite well. However today access to ICT is required for most education, employment, and commerce, and is increasingly required for travel, health, safety, daily living ...
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 25

 TERMINÉ 

LEGumes for the Agriculture of TOmorrow (LEGATO)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

The project has been conceived to promote the culture of grain legumes in Europe by identifying priority issues currently limiting grain legume cultivation and devising solutions in term of novel varietal development, culture practices, and food uses. LEGATO will develop tools and resources to enable state of the art breeding methodology and to exploit fully the breadth of genetic resources avail ...
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 32

 TERMINÉ 

European Lead Factory (EUC²LID)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
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 34

 TERMINÉ 
PANDHUB will create an integrated toolbox to aid transport operators and relevant actors in major transport hubs in the development of their current pandemic and dangerous pathogen preparedness and response plans. The project is intended to cover the extraordinary aspects specific to serious natural or man-made pathogen threats in the transport environment by providing accurate, reliable and valid ...
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 9

 TERMINÉ 

NanoBioEngineering of BioInspired BioPolymers (Nano3Bio)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

The Nano3Bio project convenes a consortium of world renowned experts from 8 EU universities, 1 large company, and 14 SME, to develop biotechnological production systems for nanoformulated chitosans. Chitosans, chitin-derived polysaccharides varying in their degree of polymerisation (DP), degree of acetylation (DA), and pattern of acetylation (PA), are among the most versatile and most promising bi ...
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 23

 TERMINÉ 
Since its inception the IMI has funded over 30 public-private partnership projects. Many of these projects are centered upon data intensive translational research and are employing integrative analysis approaches to achieve their goals. Although a common KM platform for IMI projects was envisioned in the original IMI Strategic Research Agenda it has not yet been implemented. The lack of a common p ...
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 17

 TERMINÉ 
EURenOmics will integrate several established consortia devoted to rare kidney diseases with eminent need and potential for diagnostic and therapeutic progress (i.e. steroid resistant nephrotic syndrome, membranous nephropathy, tubulopathies, complement disorders such a haemolytic uraemic syndrome, and congenital kidney malformations). The Consortium has access to the largest clinical cohorts asse ...
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 29

 TERMINÉ 
iMODE-CKD integrates multi-disciplinary expertise in proteomics, metabolomics, transcriptomics, bioinformatics, pathology, and clinical science from leading academic and industrial investigators, establishing a unique training platform on biomarker research and Systems Biology. Special emphasis is placed on the application of a wide range of –omics and bioinformatics techniques to clinical researc ...
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 10

 TERMINÉ 

Recognising Adverse Drug Reactions (WEB-RADR)

Date du début: 1 sept. 2014, Date de fin: 31 août 2017,

WEB-RADR is a consortium of leading experts in pharmacovigilance from regulatory agencies, research, academia and patient support groups. Together with EFPIA partners our aims will be to set policy & guidance and deliver robust information technology tools to address the potential for the reporting of adverse drug reactions (ADRs) through mobile applications and the recognition of drug safety sign ...
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 20

 TERMINÉ 
Despite dramatic advances in molecular and imaging technologies, there are currently no effective pharmacological treatments for the core symptoms of autism spectrum disorder (ASD). Major obstructions to this include a lack of aetiologically-driven or pathophysiologically-accurate animal models; an absence of tests that indicate efficacy; and reliance of clinical trials on DSM/ICD10 categories wh ...
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 29

 TERMINÉ 
The ABIRISK project provides an integrated approach to the study of immunization against biopharmaceuticals, bringing together a unique panel of experts from different disciplines. ABIRISK will involve many of the European leaders in rheumatology, gastroenterology, hemophilia and multiple sclerosis, caring for ~30,000 patients treated with biopharmaceuticals, with ~10,000 additional patients recru ...
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 39

 TERMINÉ 

European Patients' Academy on Therapeutic Innovation (EUPATI)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,

"The proposed project ""European Patients' Academy on Therapeutic Innovation"" (EUPATI) contributes to IMI’s goal of raising patients’ awareness and participation in pharmaceutical R&D. This patient-led academy will provide scientifically reliable, objective, comprehensive information to patients on pharmaceutical R&D. It will increase the capacity of well-informed patients to be effective advocat ...
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 33

 TERMINÉ 

Quantification of ecological services for sustainable agriculture (QUESSA)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

"The project aims to identify the key semi-natural habitats (SNH), outside and within crops, providing essential ecological services (ES). Vegetation traits will be linked to potential ES provision, case studies will measure actual ES levels and inform models which will show unused opportunities and trade-offs among ES by SNH from habitat to landscape scale. This will be achieved for a range of re ...
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 14

 TERMINÉ 
"With the use of more advanced, but difficult-to-cut materials, on ever-more sophisticated products, the need to further develop and utilise the particular capabilities of the energy beam (EB) processing techniques seem to become a key enabler for the European industry. Although they are of various nature, a set of key communalities can be identified among EB methods when considered as dwell-time ...
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 11

 TERMINÉ 

European Bank for induced pluripotent Stem Cells (EBISC)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,

EBiSC is designed to address the increasing demand by iPSC researchers for quality-controlled, disease-relevant research grade iPSC lines, data and cell services. Its goal is to demonstrate an operational banking and distribution service of iPSC lines after 3 years and to establish subsequently for Europe a centralised, not-for-profit bank providing all qualified users with access to scalable, cos ...
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 30

 TERMINÉ 

THE EUROPEAN GAME JAM LEARNING HUB (JamToday)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,

Game Jams have been organised for several years around the world and are a powerful instrument to stimulate innovation in the creation, development and deployment of educational games. Game Jam events are typically organised for 48 hours and simultaneously conducted in various locations. They offer the possibility to develop an idea into a potentially innovative solution around specific themes wh ...
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 25

 TERMINÉ 

Incorporating real-life clinical data into drug development (GETREAL)

Date du début: 1 oct. 2013, Date de fin: 31 déc. 2016,

When a new medicine reaches the market, it is accompanied by an extensive data package that provides information about the safety and efficacy of the medicine in a clinical trial setting. However, assessing the expected future value of the medicines when used in “real world” clinical practice requires additional information next to traditional (pre-authorisation) clinical trials. Regulatory, HTA ...
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 32

 TERMINÉ 

Embodied Audition for RobotS (EARS)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,

The success of future natural intuitive human-robot interaction (HRI) will critically depend on how responsive the robot will be to all forms of human expressions and how well it will be aware of its environment. With acoustic signals distinctively characterizing physical environments and speech being the most effective means of communication among humans, truly humanoid robots must be able to ful ...
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 6

 TERMINÉ 
Children with diffuse lung disease, also called childhood interstitial lung diseases (chILD), may have one of more than 200 entities, the biggest group of respiratory orphan lung diseases. Frequently undiagnosed because of lack of awareness or complex differential diagnosis, they lead to much morbidity, mortality (about 15%) and psychosocial stress for the families. Current lack of evidence based ...
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 10

 TERMINÉ 
Background:In current drug safety education and training in Europe, an integrative and translational approach is lacking. This shortfall has been identified by EUFEPS. The IMI (‘Strategic Research Agenda’), the FDA and the EMEA have also characterised this fact as a crucial gap in the education and training of scientists evaluating the safety of drug candidates and new medicines. Scope and objecti ...
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 34

 TERMINÉ 
CHEM21 is a project that will develop a broad based portfolio of sustainable technologies for green chemical intermediate manufacture aimed at the pharmaceutical industry. Initially working with the EFPIA members the collaborators of CHEM21 will analyse a number of projects that are in development to decide which the priorities are for technology development. This analysis will also be used to upd ...
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 19

 TERMINÉ 

Bottom-up Climate Adaptation Strategies towards a Sustainable Europe (BASE)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

Climate change can disrupt ecological, social and economic systems, with some regions and sectors suffering significantly. Therefore, adaptation plays a paramount role in responding to climate change. Progress has been made, but there are still important obstacles. Knowledge of the benefits and costs of adaptation is sparse, unsystematic and unevenly distributed across sectors and countries. Plan ...
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 15

 TERMINÉ 

Technology Transfer in Computing Systems (TETRACOM)

Date du début: 1 sept. 2013, Date de fin: 31 août 2016,

The mission of the TETRACOM Coordination Action is to boost European academia-to-industry technology transfer (TT) in all domains of Computing Systems. While many other European and national initiatives focus on training of entrepreneurs and support for start-up companies, the key differentiator of TETRACOM is a novel instrument called Technology Transfer Project (TTP). TTPs help to lower the barr ...
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 33

 TERMINÉ 
Commercial aircraft fault tolerant control (FTC) strategies in the flight control system (FCS) are based on fail-safe approaches whereby a nominal control law is switched first to a robust solution and then if necessary to a direct law controlling the actuators surfaces. Each component of the control law set is designed off-line and has a different level of robustness and performance. The reasons ...
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 10

 TERMINÉ 

"FrontierCities - European Cities driving the Future Internet" (frontierCities)

Date du début: 1 juil. 2014, Date de fin: 30 juin 2016,

"FrontierCities - European Cities driving the Future Internet" (FrontierCities) is a proposal presented to the FI-PPP Phase 3 CP-CSA Call. The project builds on the FI-PPP Phase I and II work, and is directly linked to the work carried out in FI-Phase II use cases INSTANT MOBILITY, and OUTSMART. While building upon Phase II, FrontierCities is however in line with the significant change in focus re ...
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 7

 TERMINÉ 

IAGOS for the GMES Atmospheric Service (IGAS)

Date du début: 1 janv. 2013, Date de fin: 30 juin 2016,

"IAGOS (In-service Aircraft for a Global Observing System), one of the European Research Infrastructures (ERI) on the ESFRI roadmap and currently in its preparatory phase, is establishing a distributed infrastructure for long-term observations of atmospheric composition on a global scale from a fleet of initially 10-20 long-range in-service aircraft of internationally operating airlines. IAGOS wil ...
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 13

 TERMINÉ 

Proton Ionization Molecular Mass Spectrometry (PIMMS)

Date du début: 1 juin 2012, Date de fin: 31 mai 2016,

"The need for quantitative and fast identification of trace gaseous compounds in complex chemical matrices continuously pushes the limits of analytical chemistry in many areas of relevance to the EU, including food, health, the environment, and security. A relatively new broad-based and rapidly growing analytical technique, proton transfer reaction mass spectrometry (PTR-MS), combines excellent c ...
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 12

 TERMINÉ 
The All-Electric Aircraft is a major target for the next generation of aircraft to lower consumption of non-propulsive power and thus fuel burn. To eliminate hydraulic circuits, pumps and reservoirs, Electro Mechanical Actuators (EMA) are mandatory but now need to meet cost, reliability and weight requirements from the airframers.ACTUATION2015 aims to develop and validate a common set of standard ...
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 56

 TERMINÉ 
The overall aim of the TACTIC project is to increase preparedness to large-scale and cross-border disasters amongst communities and societies in Europe. To achieve this, TACTIC will consider studies on risk perception and preparedness (including good practices and preparedness programmes) in order to develop a participatory community preparedness audit enabling communities to assess, impacts in a ...
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 8

 TERMINÉ 

Europeana Cloud: Unlocking Europe's Research via The Cloud (eCloud)

Date du début: 1 févr. 2013, Date de fin: 30 avr. 2016,

Europeana Cloud is a Best Practice Network, submitted under Objective 2.1.a and coordinated by the Europeana Foundation, designed to establish a cloud-based system for Europeana and its aggregators. Europeana Cloud will provide new content, new metadata, a new linked storage system, new tools and services for researchers and a new platform - Europeana Research. Content providers and aggregators, a ...
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 36