4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Towards Early Molecular Diagnostics of Schizophrenia (SZ_TEST)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
...and emotionally devastating illnesses known to man, SZ is also associated with considerable socioeconomic burden. In general, the chronic nature and the high degree of patient disability make SZ the fourth leading cause of disease burden across the globe with the management costs making up ~3% of the total healthcare budget in the Western countries. The situation is even direr in some regions, inc ...
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9
Participants partenaires
TERMINÉ
SYSTEMS BIOLOGY OF PATHWAYS INVOLVING BRAIN AGEING (AGEDBRAINSYSBIO)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
...ard project based on the integration of available transcriptomics, proteomics and metabolomics data, addition of relevant novel sets of data, their modeling and experimental testing in both human, mouse and drosophila. The concept is to identify subsets of pathways with two unique druggable hallmarks: (i) the validation of interactions occurring locally in subregions of neurons and (ii) a human an ...
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15
Participants partenaires
TERMINÉ
Detection of endpoints and biomarkers of repeated dose toxicity using in vitro systems (DETECTIVE)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,
... animal tests needs to comprise the development of biomarkers of long-term toxicity in human target cells. To this aim, the DETECTIVE project will set up a screening pipeline of high content, high throughput as well as classical functional and “-omics” technologies to identify and investigate human biomarkers in cellular models for repeated dose in vitro testing. In view of industrial use in autom ...
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15
Participants partenaires
TERMINÉ
Embryonic Stem cell-based Novel Alternative Testing Strategies (ESNATS)
Date du début: 1 avr. 2008, Date de fin: 30 sept. 2013,
...oncept study. ESNATS benefits are to increase safety due to better predictivity of human test systems, to reduce, refine and replace animal tests, to lower testing cost, and to support medium/high throughput testing. ESNATS objectives will be achieved in a 5 year multi-disciplinary collaboration of leading European researchers in alternative testing, toxicology, ESC research, genomics, modelling, ...
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