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10 projets européens trouvés

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 TERMINÉ 
Hemophagocytic lymphohistiocytosis (HLH) is a rare, devastating disease characterized by uncontrolled immune response that primarily affects young infants and children. HLH is usually fatal if untreated. Even when treated, the overall survival rate is still as low as 60-70%. No drug has been formally developed for the treatment of this disease and current treatment methods require the use of drugs ...
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 6

 TERMINÉ 
"The SO2S network seeks to exploit Singlet Oxygen (1O2) as a green and benign oxidant for use in novel synthetic methodologies, crosslinking strategies, bioconjugation procedures and materials production. The chemistry described herein generates the means to both understand and influence biological systems by providing probes and reagents – from analytical methods to new drugs - and to modulate ma ...
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 9

 TERMINÉ 

The Urban Sound Planner (SONORUS)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

"Traffic noise pollution in urban areas is a major environmental problem within the European Union. Creating an acceptable acoustic outdoor environment is a big challenge of high need. Creating as well as preserving environments, which are supportive for health and well-being in a sustainable manner is an even bigger but unavoidable task. In order to succeed, specialists are required with a broad ...
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 9

 TERMINÉ 

Cavity Quantum Optomechanics (cQOM)

Date du début: 1 juin 2012, Date de fin: 31 mai 2016,

Over the past year a new research field has emerged: cavity Optomechanics which brings the quantum regime of mechanical oscillators in reach and may allow to explore new fundamental measurements concepts, may lead to novel transducers and test quantum mechanics on a macroscopic scale. In this research field, which utilizes mechanical oscillators coupled to laser fields, Europe has played a pioneer ...
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 11

 TERMINÉ 

TargetIng novel MEchanisms of Resolution in inflammation (TIMER)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

Resolution of inflammation is a key determinant of pathology, and an active process which involves diverse pathways and molecules. The general objective of the TIMER Consortium is to identify and validate new molecules involved in the resolution of inflammation as a basis for the development of innovative therapeutic strategies in chronic inflammatory and autoimmune diseases. The project will invo ...
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 13

 TERMINÉ 
The growing development, production and use of engineered nanomaterials and associated products will increase exposure of both humans and ecosystems to these new materials. However, current knowledge is still incomplete and established test methods are as yet inappropriate to reliably assess the extent of exposure and risk of materials at the nano-scale. There is an urgent need to develop methods ...
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 32

 TERMINÉ 

Regenerating Bone defects using New biomedical Engineering approaches (REBORNE)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,

Bone is among the most frequently transplanted tissue with about 1 million procedures annually in Europe. The worldwide market of bone replacement materials is currently estimated at 5 billion € with a 10% annual growth. Despite their considerable disadvantages, including the risk of disease transfer and immunologic rejection, limited supply of bone, costs and complications, allografts and autogra ...
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 24

 TERMINÉ 

Clean European Rail - Diesel (CleanER-D)

Date du début: 1 juin 2009, Date de fin: 31 janv. 2014,

The study of CER, UNIFE, UIC and Euromot of the railway and engine manufacturing industries concluded on a risk of disruptive effect of the NRMM Directive application on the railway diesel vehicle supply market, leading to a possible risk of a partial modal shift from rail to road on regional passenger lines and freight transportation specialized routes, with even foreseeable consequences on the o ...
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 27

 TERMINÉ 

Intelligent Mold for Productivity Enhancement (Mold4ProdE)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2013,

The constant demand for diversified/personalised consumers' goods leads to decrease time-to-market, and to plastic injection molds with smaller batch production, with no stock acceptable for cost and quality reasons. This generates huge productivity losses in the molding industry: - Tool Tuning is too long for tool makers before delivery of a turn key mold. - New production run set-up time is too ...
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 26

 TERMINÉ 

Pemphigus - From autoimmunity to disease (Pemphigus)

Date du début: 1 mai 2008, Date de fin: 31 oct. 2011,

Pemphigus is a potentially lethal bullous disease of the skin and mucosa and may be considered as a paradigmatic organ-specific autoimmune disease due to 1) its well-defined autoantigens, 2) the knowledge of critical events of its immune pathogenesis and 3) the reproducibility of major clinical and pathogenic features in suitable animal models. Overall, understanding the etiopathogenesis of pemphi ...
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 7