3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
First Targeted Therapy to FIGHT Hemophagocytic Lymphohistiocytosis (HLH): A novel approach to HLH (FIGHT-HLH)
Date du début: 1 juil. 2012, Date de fin: 31 juil. 2017,
...s animals from death in murine models of primary HLH. In patients, evidence points towards a correlation between levels of IFNγ and disease activity. In order to target IFNγ in patients with HLH, NovImmune generated and characterized a fully human mAb, NI-0501, that neutralizes the biological activity of human IFNγ. This consortium proposes an adaptive clinical trial with a pilot and a pivotal pha ...
Voir le projet
6
Participants partenaires
TERMINÉ
OSTEOIMMUNE - Unraveling the Interactions between the Immune System and Bone (OSTEOIMMUNE)
Date du début: 1 juin 2012, Date de fin: 31 mai 2016,
Inflammatory rheumatic diseases affect millions of European citizens causing chronic pain, disability and premature death. Curative treatments are lacking. Conventional research often focuses on one single organ system such as the bone or the immune system and. ignores interactions between organ systems. OSTEOIMMUNE is a supra-disciplinary training network that targets this gap by providing compre ...
Voir le projet
12
Participants partenaires
TERMINÉ
TargetIng novel MEchanisms of Resolution in inflammation (TIMER)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
Resolution of inflammation is a key determinant of pathology, and an active process which involves diverse pathways and molecules. The general objective of the TIMER Consortium is to identify and validate new molecules involved in the resolution of inflammation as a basis for the development of innovative therapeutic strategies in chronic inflammatory and autoimmune diseases. The project will invo ...
Voir le projet