2 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Integrating bioinformatics and chemoinformatics approaches for the development of expert systems allowing the in silico prediction of toxicities (ETOX)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2016,
The eTOX consortium proposes to develop innovative methodological strategies and novel software tools to better predict the toxicological profiles of new molecular entities in early stages of the drug development pipeline. This will be achieved by coordinating the efforts of specialists from academia and SMEs in the wide scope of disciplines that are required to move towards a more reliable modell ...
Voir le projet
30
Participants partenaires
TERMINÉ
Safety Evaluation of Adverse Reactions in Diabetes (SAFEGUARD)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,
"In 2010 a widely marketed drug for the treatment of type 2 diabetes (T2DM) (rosiglitazone) was taken from the market as it was associated with an increased risk of myocardial infarction, a T2DM complication it was actually supposed to prevent. This example shows several things. First, the approval requirements do not guarantee a longer term positive benefit risk profile. Second, large scale postm ...
Voir le projet