5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
European Prevention of Alzheimer’s Dementia Consortium (EPAD)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,
Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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40
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TERMINÉ
Comparing the effectiveness of palliative care for elderly people in long term care facilities in Europe (PACE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
"Aging populations, rising costs and sustainable delivery of high-quality care are increasingly common concerns in all EU countries. PACE aims to perform comparative effectiveness research concerning palliative care in long term care facilities (LTCFs) in Europe. While a growing number of older people will require palliative care in institutionalized settings, palliative care has only recently beg ...
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13
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TERMINÉ
From Patient Data to Clinical Diagnosis in Neurodegenerative Diseases (PredictND)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
Dementia is a growing health problem with enormous costs to society: the costs currently equal 1% of the global gross-domestic product and a three-fold increase to 115 million dementia cases is expected by 2050. Addressing this grave human and economic challenge requires efficient solutions that do not exist yet: tools to detect and diagnose persons at an early phase, and interventions for delayin ...
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10
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TERMINÉ
Identifying Inflammatory Bowel Disease causative genes through trans-eQTLs mapping within GWAS loci (TRANS_CEDAR)
Date du début: 1 mars 2014, Date de fin: 29 févr. 2016,
Life-time prevalence of inflammatory bowel disease (IBD) is reaching an alarming rate of > 1/400 in industrialized societies. Improved understanding of disease pathogenesis is essential to develop more effective preventive, diagnostic and therapeutic measures. Genome-wide association studies (GWAS) have identified ~ 160 risk loci contributing to inherited predisposition to Crohn's disease and/or ...
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1
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TERMINÉ
Identification of regulator variants in Rheumatoid Arthritis and Crohn’s Disease ("""ChIP Seq RA CD""")
Date du début: 1 juin 2012, Date de fin: 31 mai 2015,
Rheumatoid Arthritis (RA) and Crohn’s disease (CD) are two common chronic autoimmune and complex diseases where individual susceptibility is determined by a combination of environmental and genetic factors. Almost all of the ~100 risk alleles discovered through recent genetic studies fall in non-coding region and have an elusive function. We hypothesize that risk alleles impact gene regulation by ...
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