6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Translating disease to cardiovascular health (TransCard)
Date du début: 1 sept. 2013, Date de fin: 31 août 2018,
Cardiovascular disease (CVD) is the leading cause of death in Europe and the world. Drugs that lower cholesterol in blood are the most efficient drugs used to date but we are currently still facing a 50-70% residual risk of suffering from CVD. This clearly illustrates an urgent need for the identification, characterization and validation of novel therapeutically relevant targets. Over the last dec ...
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8
Participants partenaires
TERMINÉ
A systems biology approach to RESOLVE the molecular pathology of two hallmarks of patients with metabolic syndrome and its co-morbidities; hypertriglyceridemia and low HDL-cholesterol (RESOLVE)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
"Through combining basic pre-clinical and clinical research, network analysis and computational modelling, RESOLVE aims at resolving the disturbed dynamics and mechanisms underlying the high triglyceride (HTG) and low high-density lipoprotein cholesterol (HDL-C) phenotype and insulin resistance in patients with metabolic syndrome (MetS) and its associated co-morbidities (cardiovascular disease, CV ...
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14
Participants partenaires
TERMINÉ
From sea-bed to test-bed: harvesting the potential of marine microbes for industrial biotechnology (SeaBioTech)
Date du début: 1 août 2012, Date de fin: 31 juil. 2016,
SeaBioTech is a 48-month project designed and driven by SMEs to create innovative marine biodiscovery pipelines as a means to convert the potential of marine biotechnology into novel industrial products for the pharmaceutical (human and aquaculture), cosmetic, functional food and industrial chemistry sectors. SeaBioTech will reduce barriers to successful industrial exploitation of marine biodivers ...
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17
Participants partenaires
TERMINÉ
INOvative Energy MANagement System for Cargo SHIP (INOMANS²HIP)
Date du début: 1 mai 2011, Date de fin: 30 nov. 2015,
The global optimization of energy systems aboard future and currently operating cargos is crucial to reduce greenhouse gas emission in a substantial and cost effective way. It is also of major economic interest in the merchant marine sector.A holistic approach considering the overall production and management of energy aboard ships (including propulsion systems and energy output optimization) is t ...
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12
Participants partenaires
TERMINÉ
To decipher the optimal management of systemic sclerosis (DESSCIPHER)
Date du début: 1 déc. 2012, Date de fin: 30 nov. 2015,
The current approach to diagnosis and management of the rare disease systemic sclerosis (SSc) is based on American College of Rheumatology criteria with low sensitivity and few validated recommendations for the therapy of the disease and its manifold organ manifestations. To overcome these shortcomings, the DeSScipher project will use the multinational, prospective and open EUSTAR (Scleroderma Tri ...
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15
Participants partenaires
TERMINÉ
HER Imaging and Molecular Interaction Mapping in Breast Cancer (IMAGINT)
Date du début: 1 mai 2011, Date de fin: 30 avr. 2015,
The aim is to develop tools for imaging and characterising protein/protein and protein/RNA interactions in cancer using Designed Ankyrin Repeat Proteins (DARPins). DARPins are small, ultrahighly stable, antibody-like proteins that bind specific targets with high affinity in monovalent form and are readily engineered for site-specific chemical modification. The exemplar protein family will be EGFR, ...
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