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"LAntibiotic Production: Technology, Optimization and improved Process" (LAPTOP)

Date du début: 1 juil. 2010, Date de fin: 30 juin 2013,

"The focus of this proposal is to develop an economically viable production process for the lantibiotic NAI-107, a new antibiotic with the potential to treat life-threatening infections caused by multidrug-resistant Gram-positive pathogens. NAI-107 is produced by fermentation of the actinomycete Microbispora sp., is undergoing formal toxicology studies and is expected to enter Phase I clinical tri ...
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