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6 projets européens trouvés

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 TERMINÉ 

The Extracellular Matrix in Epileptogenesis (ECMED)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Over 50 million people worldwide have epilepsy and 30% are resistant to our present therapies. Epilepsy, therefore, comprises a major burden to society and so there is a pressing need for new approaches to treatment. The brain extracellular matrix (ECM) plays a critical role in governing brain excitability and function. Although research into the role of the ECM in neuronal signalling and network ...
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 10

 TERMINÉ 

Brain Imaging Return to Health (r'BIRTH)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

Extended lifespan is a new and permanent feature of human life globally. The demographic for population growth of persons over 60 years is predicted to expand by 70% and 400% respectively in developed and less developed regions during the coming decades. Ageing, is accompanied by cognitive decline and greater risk of depression and anxiety. Major drug companies have recently cutback significantly ...
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 10

 TERMINÉ 

Miniature Insect Model for Active Learning (MINIMAL)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,

Biology provides the inspiration for a vision of small low-power devices that are able to learn rapidly and autonomously about environmental contingencies, enabling prediction and adaptive anticipatory action. Larval Drosophila have fewer than 10,000 neurons, yet express a variety of complex orientation and learning behaviours, including non-trivial anticipatory actions requiring context-dependent ...
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 4

 TERMINÉ 
Brain disorders impose an increasing economical and social burden in the member states of the European Union (EU). For most neurodegenerative diseases and many neuropsychiatric disorders no efficient treatment is available and no cure exists. In the next coming years the number of particularly elderly people suffering from brain disorders will tremendously increase. Predictions from the turn of th ...
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 10

 TERMINÉ 
Brain disorders, in particular neurodegenerative diseases and mental illnesses are among the most prevalent and debilitating diseases. Because they are chronic, quality of life and socio-economic prospects are dramatically impaired. Increased life expectancy further enhances the impact of brain dysfunction on society. In coming decades this burden will grow into one of most pressing and costly pro ...
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 14

 TERMINÉ 

Restorative Plasticity At Corticostriatal Excitatory Synapses (REPLACES)

Date du début: 1 nov. 2008, Date de fin: 30 avr. 2013,

"Long-lasting, activity-dependent synaptic changes are thought to underlie the ability of the brain to translate experiences into memories and seem to represent the cellular model underlying learning and memory processes. Alteration of brain plasticity may lead to the motor and cognitive disturbances observed in neurodegenerative diseases. Therapeutic approaches targeting synaptic plasticity could ...
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