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Molecular recognition of bacterial cell wall peptidoglycans and related molecules by innate immune receptors (PGN-INNATE)
Date du début: 1 janv. 2014, Date de fin: 1 janv. 2019,
The immune system of higher organisms is using pattern recognition receptors (PPR) of the host cell to fight pathogenic bacteria by recognizing molecular signatures called Pathogen Associated Molecular Patterns (PAMP) unique to the bacteria but absent from the host. Bacterial cell wall peptidoglycan (PGN), a polymer of disaccharide-pentapeptide repeating units is one of the most important PAMPs. F ...
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