3 projets européens trouvés
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TERMINÉ
Sphingolipid homeostasis: from basic biology to applications (SPHINGONET)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2016,
SPHINGONET was inspired by a common vision of its partners on the training of researchers in the field of sphingolipid homeostasis and body-wide sphingolipid signaling networks using innovative technological approaches. Dysregulation of sphingolipid balances contributes to a broad range of pathological processes, spanning neurodegeneration, asthma, autoimmune disease, insuline resistance, obesity ...
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10
Participants partenaires
TERMINÉ
Chemical Biology for Tuberculosis Research (ChemBio4TB)
Date du début: 1 juil. 2010, Date de fin: 30 juin 2012,
The aim of the proposal is the establishment of a yeast-three hybrid system for the identification of mycobacterial proteins that bind to selected small molecules. It is envisioned to use the system to (i) find targets of active molecules that have been identified in whole cell screenings; (ii) identify mycobacterial proteins that activate or deactivate drugs; (iii) establish simple assays for pro ...
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1
Participant partenaire
TERMINÉ
Outer membrane protein complexes of mycobacteria (MYCOOMP)
Date du début: 1 sept. 2007, Date de fin: 31 août 2009,
Tuberculosis is a severe human disease and the appearance of a growing number of multiple-drug resistant Mycobacterium tuberculosis strains makes it a necessity to learn more about cell wall formation, drug uptake and drug mechanisms. A major hurdle for the development and improvement of newug candidates is the notorious difficulty in identification and characterization of the corresponding drug t ...
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