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Characterisation of the functional heterogeneity of lymphoid organ dendritic cells by proteomic analysis of plasma membrane and endosomal proteins (DCSUBTYPESPROTEOMICS)
Date du début: 1 oct. 2007, Date de fin: 30 sept. 2010,
Dendritic cells (DC) are unique in their capacity to induce and regulate immune responses. Their special abilities in pathogen detection, antigen processing and presentation, and communication to T cells are determined by plasma membrane and endosomal proteins. Our knowledge of DC biology is mainly based on studies of in vitro generated-DC, which are not representative of those found in vivo. Clea ...
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