2 projets européens trouvés
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TERMINÉ
Exploring ’synthetic lethality’ and ’synthetic viability’ to elucidate responses of breast and prostate cancer cells to DNA damage and treatment resistance (SYNvia)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2014,
The key objective of this Marie Curie project is to explore the ‘synthetic lethality’ and ‘synthetic viability’ principles applied to DNA damage response (DDR) mechanisms and help derive new therapies and/or biomarkers for personalized treatment of breast and prostate cancer. As these tumors are major causes of mortality and morbidity in Europe, and this multifaceted project in an outstanding host ...
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TERMINÉ
"Systems-Level, Multi-layer Understanding of Cellular Responses to Ionizing Radiation" (TRIREME)
Date du début: 1 janv. 2009, Date de fin: 31 déc. 2011,
"The TRIREME project aims at developing and implementing a multidisciplinary strategy for a systems-level analysis of a cornerstone of cellular homeostasis – the DNA damage response (DDR). The DDR is a complex signaling network that is responsible for maintaining the stability and integrity of the cellular genome in the face of DNA damage. DDR defects underlie acute and chronic forms of human ailm ...
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