7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Real-time monitoring of load induced remodeling in tissue-engineered bone (REMOTE)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
"The maintenance of the skeleton is tightly coupled with balanced bone formation and resorption processes that are mediated by osteoblasts and osteoclasts, respectively. Loss of this balance results in skeletal pathologies representing some of the most significant public health threats faced by the growing and ageing population. Tissue engineering investigates various health aspects such as drug d ...
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1
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TERMINÉ
A systems biology approach to RESOLVE the molecular pathology of two hallmarks of patients with metabolic syndrome and its co-morbidities; hypertriglyceridemia and low HDL-cholesterol (RESOLVE)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
"Through combining basic pre-clinical and clinical research, network analysis and computational modelling, RESOLVE aims at resolving the disturbed dynamics and mechanisms underlying the high triglyceride (HTG) and low high-density lipoprotein cholesterol (HDL-C) phenotype and insulin resistance in patients with metabolic syndrome (MetS) and its associated co-morbidities (cardiovascular disease, CV ...
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14
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TERMINÉ
Using chemical-biology to synthesis and study nuclear receptor proteins (CHEMbioNMR)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2014,
The rapidly growing field of Chemical Biology combines the power of synthetic chemistry with the spectrum of micro- and molecular biology techniques, thus important challenges in medicine can be addressed in revolutionary new ways. This innovative methodology allows problems associated with studying diseases and designing novel drug-like molecules to be tackled in a unique approach. A recent examp ...
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1
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TERMINÉ
Targeting the biological imaging market with multifunctional fluorescent nanoparticles (BioNLight)
Date du début: 1 août 2012, Date de fin: 31 juil. 2013,
BioNLight has been designed to investigate the prospective of commercially exploiting our multimodal nanoparticle technology in the biological imaging market. The introduction of this technology will open up an entirely-new window of molecular imaging possibilities, thereby supporting advances in biology, drug discovery & development and diagnostics.Funded by ERC, Prof. Brunsveld and colleagues ha ...
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1
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TERMINÉ
Disc-degeneration linked pathologies: novel biomarkers and diagnostics for targeting treatment and repair (Genodisc)
Date du début: 1 mars 2008, Date de fin: 28 févr. 2013,
Disorders arising from degeneration of the intervertebral disc are an enormous clinical and financial burden on European societies. Most of the burden arises from 10% of patients who become chronically disabled. Any factor which will improve treatment of back pain sufferers or prevent development of chronic disability would have an important impact both on society and in improving quality of life ...
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10
Participants partenaires
TERMINÉ
Osteoporotic Virtual Physiological Human (VPHOP)
Date du début: 1 sept. 2008, Date de fin: 31 oct. 2012,
Nearly four million osteoporotic bone fractures cost the European health system more than 30 billion Euro per year. This figure could double by 2050. After the first fracture, the chances of having another one increase by 86%. We need to prevent osteoporotic fractures. The first step is an accurate prediction of the patient-specific risk of fracture that considers not only the skeletal determin ...
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21
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TERMINÉ
"Supramolecular Medicine: Modular, Double Dynamic and Orthogonal Functionalization of Supramolecular Biomaterials" (SUPMED)
Date du début: 1 mars 2009, Date de fin: 28 févr. 2011,
"The main objective of this project is to create a new generation of smart biomaterials with great potential for tissue engineering and controlled drug delivery. Supramolecular polymers based on quadruple hydrogen bonding ureido-pyrimidinone (UPy) moieties (developed by the host group of Prof. Dr. E. W. Meijer in Eindhoven University of Technology, the Netherlands) will be employed as a basic scaf ...
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