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21 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

Novel metal clusters in protein clefts (METCLEF)

Date du début: 1 sept. 2008, Date de fin: 31 août 2009,

... to establish a programme as an independent research worker, acquire new cutting-edge skills, participate in multicultural research teams, experience the benefits of cultural diversity and acquire an international profile for his career. The project will have a significant impact on scientific and technological links between Europe and India, in particular with the Indian Institute of Technology i ...
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 1

 TERMINÉ 

Molecular and cellular heterogeneity of tumour stem cells in human glioblastoma (tumourstemcells)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2013,

...gy and will shed new lights on the function of tumour stem cells in human glioblastoma.The project will be carried out at the Department of Clinical Neurosciences of the University of Cambridge in an international and stimulating institute that is ranked first of all the UK’s top medical schools in both teaching and research and is one of the top Universities in the world. The applicant has a stro ...
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 1

 TERMINÉ 

BIO-IMAGing in research INnovation and Education (BIO-IMAGINE)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

This Project aims at enhancing the potential of the Nencki Institute to participate actively in international research in neurobiology that uses cutting edge biological imaging techniques. Over the recent years bio-imaging has become the primary investigation method at the Institute and represents one of its strategic development areas for the next decade. A multi-level application of bio-imaging ...
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 1

 TERMINÉ 

Real-Time Studies of Biological NanoMachines in Action by NMR (NanoLife@Work)

Date du début: 1 juil. 2012, Date de fin: 30 juin 2014,

... the candidate will receive first-class training and career development at a major European structural biology centre. The trans-national move to the host institute will help candidate to build international collaborations and acquire new skills and experience. This diversification and enhancement of scientific and professional competences will enable the candidate to reach a position of professio ...
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 1

 TERMINÉ 

STRENGTHENING COOPERATION IN MOLECULAR BIOMEDICINE BETWEEN EU AND UKRAINE (COMBIOM)

Date du début: 1 déc. 2011, Date de fin: 31 mai 2015,

...nostics and therapy of oncological and neurodegenerative diseases. Widening and deepening the existing bilateral collaboration with two EU partners: Gustave Roussy Institute of Oncology, France, and International Institute of Molecular and Cell Biology, Poland, will provide creation of a new research consortium for enhanced involvement of the Ukrainian research center into the ERA (first objectiv ...
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 3

 TERMINÉ 

Fishing for Medicines and their targets using Zebrafish models of human diseases (FISHMED)

Date du début: 1 déc. 2012, Date de fin: 31 mai 2016,

The International Institute of Molecular and Cell Biology (IIMCB) was created with the support of UNESCO, Polish Academy of Sciences (PAN) and the Polish Government and started its activity in 1999. The Institute is a unique, innovative, based on the best world standards research centre, known for it’s scientific excellence. In 2010, IIMCB was ranked first among 36 biological institutions in Polan ...
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 1

 TERMINÉ 

CRG International Postdoctoral Fellowship Programme in Life Sciences (ImPuLSe)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

The proposed “CRG International Postdoctoral Fellowship Programme in Life Sciences” (ImPuLSe) builds on the existing Fellowship Programme “International Interdisciplinary Postdoctoral Programme (InterPod) running from 2010 to 2014, co-funded by the FP7 COFUND scheme. ImPuLSe aims at enabling outstanding junior scientists of all nationalities to develop a competitive research project in life scienc ...
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 1

 TERMINÉ 

Bacterial host cell death modulators – a genetic approach to identify anti-apoptotic factors of Chlamydia trachomatis and to explore their role during infection (GenChlaDeath)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2017,

...the anti-apoptotic trait may be a potential new drug target. The project offers Dr. Sixt extensive training that is highly complementary to her previous research experiences. The acquired skills, international experience, and newly established contacts will place her in an excellent position to take a leading role in the further development of this scientific field and will enable her to implement ...
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 1

 TERMINÉ 

Mitotis-induced entosis and its role in cancer (ENTOSIS2013)

Date du début: 1 oct. 2014, Date de fin: 1 avr. 2017,

...ork, we will pursue this novel finding by studying the:1) Molecular mechanisms that promote mitosis-induced entosis2) Biophysical changes which accompany mitosis to induce entosis (multidisciplinary, international collaboration)3) Occurrence and significance of mitosis-induced entosis in human cancer4) Relevance of entosis to anti-mitotic cancer therapiesThe host lab is one of a few groups globall ...
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 1

 TERMINÉ 

An interdisciplinary approach to uncover the mechanisms of progression of cartilage damage at the cellular and tissue levels (INpaCT)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

...light on the key mechanobiological pathways by which cartilage cells maintain healthy tissue or mount a healing response following tissue injury and excessive loading. This project is conducted as an international collaboration between University of Eastern Finland, Kuopio, Finland and Massachusetts Institute of Technology, Cambridge, USA. This represents a unique opportunity to bring together the ...
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 1

 TERMINÉ 

Long-term, prospective study evaluating clinical and molecular biomarkers of epileptogenesis in a genetic model of epilepsy – tuberous sclerosis complex (EPISTOP)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Despite a great progress in the management of epilepsy, still one third of patients is refractory to available medications. The incidence of epilepsy is highest in infancy and 50% of children experience epilepsy-related comorbidities, such as developmental delay and autism. The development of epilepsy (epileptogenesis), extensively studied in animals, is barely studied in humans, as patients usual ...
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 16

 TERMINÉ 

Structural studies of Nucleotide Excision Repair complexes (NERCOMP)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,

"DNA damage caused by chemical and physical factors can lead to detrimental effects to the cell and must be corrected. One of the primary pathways to achieve this repair is nucleotide excision repair (NER). In NER, the DNA damage is first located, a stretch of bases harboring the lesion is removed, and the gap is filled by a DNA polymerase. The unique feature of NER is its ability to correct a wid ...
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 1

 TERMINÉ 

Better Experimental Screening and Treatment for Primary Ciliary Dyskinesia (BESTCILIA)

Date du début: 1 déc. 2012, Date de fin: 31 mai 2016,

Primary Ciliary Dyskinesia (PCD) is a rare genetically heterogeneous disorder which results from dysfunction of motile hair-like organelles (cilia) that results in severe, chronic airways disease. Due to other cilia-related disease mechanisms several other organ systems like the heart can be affected. The complexity of the disease phenotype, late diagnosis, as well as lack of evidence based manage ...
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 12

 TERMINÉ 

Breaking the code of RNA sequence-structure-function relationships: New strategies and tools for modelling and engineering of RNA and RNA-protein complexes (RNA+P=123D)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

Ribonucleic acid (RNA) is a large class of macromolecules that plays a key role in the communication of biological information between DNA and proteins. RNAs have been also shown to perform enzymatic catalysis. Recently, numerous new RNAs have been identified and shown to perform essential regulatory roles in cells.As with proteins, the function of RNA depends on its structure, which in turn is en ...
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 1

 TERMINÉ 

Effective Technology Transfer in Biotechnology (ETTBio)

Date du début: 31 déc. 2011, Date de fin: 30 déc. 2014,

ETTBio addresses the challenging issue of still unused economic potential of research institutes and universities as source for innovation and therefore efficient regional economic development. ETTBio has a sectoral focus on biotechnology for the following reasons: 1) Biotechnology is considered a key sector (and key enabling technology) in Europe for the 21st century, 2) it has very specific char ...
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 10

 TERMINÉ 

Transport and signalling in Polarized Cells (TRANSPOL)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2014,

.... A training in scientific and complementary skills including soft skills/4. An in-depth scientific training focused on a specific PhD topic/5. Doctoral examination under the auspices of external international examiners."
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 11

 TERMINÉ 

Engineered Sequence-Specific RNases: New Reagents for RNA biotechnology (ERNASES)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2013,

The basic idea to be taken to the proof of concept is creation of novel molecular biology tools, ie. enzymes acting on DNA/RNA hybrids and dsRNA that are able to cut the RNA strand(s) in a site specific manner. We have already created prototypic proteins of those two classes of ‘RNA restriction enzymes’ and performed initial steps towards commercialization of the project. We are applying for fundi ...
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 1

 TERMINÉ 

Exgenome Molecular Enzymes (EXGENOMES)

Date du début: 1 déc. 2011, Date de fin: 30 nov. 2013,

"The main objective of the EXGENOMES project is to develop new and improved thermostable enzymes for use, as reagents, in large-scale DNA synthesis and/or that can act on unnatural components such as in LNA (Locked Nucleic Acids). The target source for the new enzymes is a range of self-replicating mobile genetic elements (phages, plasmids and transposons) from thermophilic bacteria. Increased un ...
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 8

 TERMINÉ 

Structural Biology of Membrane Proteins (SBMPs)

Date du début: 1 sept. 2008, Date de fin: 31 août 2012,

...network combines 12 academic research groups and 3 industrial companies interested in collaborating with these groups and involved in drug discovery or scientific equipment for SBMP. These groups are internationally recognized for analysing the structure and dynamics of membrane proteins by a combination of experimental and theoretical approaches: in vivo and in vitro expressions systems, function ...
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 12

 TERMINÉ 

Proteins in Health and Disease (HEALTH-PROT)

Date du début: 1 avr. 2009, Date de fin: 31 mars 2012,

This project is targeted at continuation and expansion of activities initiated as the FP5 Centre of Excellence in Molecular Bio-Medicine (CEMBM). In the past as the Centre of Excellence we developed an advanced methodology of analysis of complex protein structures with the use of cell and molecular biology techniques, biochemical methods, crystallographic analysis and computer modelling. Our goal ...
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 1

 TERMINÉ 

GSK-3 in neuronal plasticity and neurodegeneration: basic mechanisms and pre-clinical assessment (NEURO.GSK3)

Date du début: 1 oct. 2008, Date de fin: 31 déc. 2011,

"Neuronal circuits in mammalian brain act predominantly via excitatory synapses on dendritic spines. Formation of new spines in adult brain constitutes the structural basis of neuronal plasticity. The underlying molecular mechanisms remain largely unknown but depend essentially on kinase-dependent signalling pathways. Final formation of synapses on spines depends on dynamic interactions of microtu ...
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 7