5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Servicing the European Biomedical Research Community: Archiving and Dissemination of Mouse Models of Human Disease (EMMAservice)
Date du début: 1 janv. 2009, Date de fin: 31 déc. 2012,
The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:1) Develop a series of mutant alleles for every gene in the mouse genome2) Determine the phenotypic consequences of each mutation3) Identify mouse models for the complete d ...
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11
Participants partenaires
TERMINÉ
Defining the molecular basis of type 2 diabetes predisposition through targeted sequencing of the CREBBP-interacting gene network (T2DCREBBP)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2015,
...urther functional studies. As well as the intrinsic scientific merit of this proposal, the research outlined will provide extensive training in state-of-the-art experimental and analytical methods in human genetics
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1
Participant partenaire
TERMINÉ
EPIGENomic markers for AIR pollution-induced health effects (EPIGENAIR)
Date du début: 1 mai 2014, Date de fin: 30 avr. 2016,
...nts by profiling full genome methylation data. For this project I will combine exposure and epigenetic data from three large prospective studies of over 1200 individuals from the ESCAPE (FP7), HuGeF (Human Genetics Foundation, Italy) and EnvironGenoMarkers (FP7) studies. I will explore the association of genome wide DNA methylation (Illumina 450K) with ambient air pollution in healthy subjects (n= ...
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2
Participants partenaires
TERMINÉ
Lifecourse biological pathways underlying social differences in healthy ageing (LIFEPATH)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,
"The dramatic differentials in healthy ageing, quality of life and life expectancy between individuals of different socioeconomic groups, is a major societal challenge facing Europe. The overarching aim of the LIFEPATH project is to understand the determinants of diverging ageing pathways among individuals belonging to different socio-economic groups. This will be achieved via an original study de ...
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18
Participants partenaires
TERMINÉ
EPIC-CVD: Individualised CVD risk assessment: tailoring targeted and cost-effective approaches to Europe's diverse populations (EPIC-CVD)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
"EPIC-CVD's overarching goal is to provide clinicians and policy-makers with a menu of evidence-based options for cost-effective individualised risk assessment that enables the EU's increasingly resource-constrained economies to achieve more personalised predictive medicine in harmony with Europe's diverse cultures and healthcare systems.We will achieve this through developing and validating innov ...
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