3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Genomic diagnostics beyond the sequence (BeyondSeq)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,
...solution and throughput. In contrast, next generation sequencing (NGS) based diagnostics provides single base resolution and high throughput but suffer from short reads that prevent analysis of large genomic aberrations as well as being prone to PCR-amplification bias and erasure of epigenetic information. This proposal aims to bridge the gap between these domains by analyzing long individual DNA ...
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8
Participants partenaires
TERMINÉ
European Training Network on Cancer-Induced Bone Diseases (BONE-NET)
Date du début: 1 févr. 2011, Date de fin: 31 janv. 2015,
...then seek to identify and develop molecularly-targeted therapies. BONE-NET’s primary objective will be to train 11 early-stage (ESR) and 3 experienced (ER) researchers in technical skills such as genomics, proteomics, advanced microscopical methods, animal experimentation, noninvasive in vivo imaging methodologies and drug development. None of the participating laboratories use all of these approa ...
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11
Participants partenaires
TERMINÉ
High Resolution Microscopy in the DNA Damage Response (Image DDR)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2012,
Background: The DNA damage response (DDR) is a specialised stress response fundamental to maintaining genome integrity and suppressing tumour formation. Traditional molecular and cellular biology, combined with genetics and biochemistry, have led to an understanding of the architecture of the DDR in a variety of model organisms and in human cells. These studies have employed populations of cells/ ...
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