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36 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

European AIDS Vaccine Initiative 2020 (EAVI2020)

Date du début: 1 nov. 2015, Date de fin: 31 oct. 2020,

HIV-1 is responsible for a global pandemic of 35 million people, and continues to spread at a rate of >2 million new infections/year. It is widely acknowledged that a protective vaccine would be the most effective means to reduce HIV-1 spread and ultimately eliminate the pandemic, while a therapeutic vaccine may help mitigate the clinical course of disease and lead to strategies of viral eradicati ...
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 27

 TERMINÉ 

iABC Programme (IABC PROGRAMME)

Date du début: 1 août 2015, Date de fin: 31 juil. 2020,

Cystic Fibrosis (CF) is a common fatal inherited disease with a frequency of 1 in 2500 live births, affecting approximately 36,000 (0.737/10,000) people in the EU. Chronic bacterial pulmonary infection leading to an irreversible decline in lung structure and function is the main cause of mortality and morbidity in patients with CF, with more than 95% of deaths due to respiratory failure. Pseudomon ...
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 21

 TERMINÉ 

Conservative iron chelation as a disease-modifying strategy in Parkinson’s disease: a multicentric, parallel-group, placebo-controlled, randomized clinical trial of deferiprone (FAIR-PARK-II)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,

Parkinson’s disease (PD) is a major, chronic, non-communicable disease and the 2nd most frequent neurodegenerative disorder worldwide. Excess iron is primarily detected in the substantia nigra pars compacta, where dopaminergic neurons are exposed to high levels of oxidative stress produced by mitochondrial disorders and dopamine metabolism. Our previous preclinical, translational and pilot clinica ...
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 17

 TERMINÉ 

Evaluating mHealth technology in HIV to improve Empowerment and healthcare utilisation: Research and innovation to Generate Evidence for personalised care (EmERGE)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,

EmERGE will develop a mHealth platform to enable self-management of HIV in patients with stable disease. The platform will build upon and integrate the existing mHealth solutions operated by pioneering healthcare providers in the UK and Spain and apply a rigorous co-design approach to ensure patient and clinician input to the solution. The platform will provide users with web based and mobile devi ...
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 13

 TERMINÉ 

Cost effective self-management of urinary incontinence addressed to women across Europe (WOMEN-UP)

Date du début: 1 févr. 2015, Date de fin: 31 juil. 2018,

Urinary incontinence (UI), considered as a disease according to the World Health Organization (WHO), is not a life-threatening condition, but causes a very negative impact on daily living and quality of life. 56 million European citizens are affected by UI, which represents a serious impairment to the quality of their professional and personal life. Recent statistics show that 346 million people ...
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 9

 TERMINÉ 

Consortium on Organ Preservation in Europe (COPE)

Date du début: 1 janv. 2013, Date de fin: 30 juin 2018,

The discrepancy between organ supply and demand remains the biggest challenge facing the transplant community today. In order to increase the amount of available donor organs, transplant specialists are increasingly turning to sub-optimal donor organs. Organs from such donors, usually have normal or near normal function before death, but retrieval, storage and transplantation cause progressive inj ...
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 16

 TERMINÉ 

European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,

ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients. Servicing multinational trials started during its preparatory phase, and it now applies for an ERIC status by 2011. The ERIC budget will be restricted to core activities re ...
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 48

 TERMINÉ 

A FRAMEWORK FOR USER CENTRED PRIVACY AND SECURITY IN THE CLOUD (CLARUS)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2017,

Although cloud computing offers many benefits, security issues such as confidentiality and privacy are still major concerns to those intending to migrate to the cloud. Traditional cloud security has been based on assurance to customers that cloud providers follow sound security practices. As a result, current security mechanisms are commonly located within the cloud platform, hence compelling cust ...
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 10

 TERMINÉ 

Implications of copy number variants of the genome in the etiology and progression of colorectal cancer (COLONGEVA)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,

"Cancer susceptibility genes involved in Mendelian inherited forms of colorectal cancer (CRC) (e.g., Lynch Syndrome) may account for only 5% of all CRC cases. However, increased cancer risk because of a positive family history may vary from 25 up to 40%, and the genetic basis for this familial aggregation remains largely unknown. Recently, high-resolution genomic strategies have revealed an unprec ...
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 1

 TERMINÉ 

European Multicentre Tics in Children Studies (EMTICS)

Date du début: 1 déc. 2011, Date de fin: 31 mai 2017,

This project will undertake pre-clinical and cohort studies that address susceptibility factors for paediatric and adolescent tic disorders, with a particular focus on comorbid obsessive-compulsive symptomatology, from clinical, epidemiological, genetic, microbiological and immunological angles. EMTICS aims to elucidate the complex aetiology of the onset and clinical course of chronic tic disorder ...
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 33

 TERMINÉ 

IMmune MOdulating strategies for treatment of MErkel cell Carcinoma (IMMOMEC)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

"Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer of the skin associated with the recently discovered, common Merkel cell polyomavirus (MCV). With an incidence of 0.44 per 100,000 MCC is a very rare cancer. Notably, however, although MCC is 40 times less common than malignant melanoma, MCC has a dramatically higher mortality rate than melanoma rendering MCC to ...
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 11

 TERMINÉ 

Benchmarking Integrated Care for better Management of Chronic and Age-related Conditions in Europe (PROJECT INTEGRATE)

Date du début: 1 sept. 2012, Date de fin: 31 août 2016,

"INTEGRATE aims at gaining valuable insights into integrated care, starting from the premise that it offers benefits for patients and for Europe’s health and social security systems, which are facing the challenges of an ageing population and increased chronic conditions. For these benefits to be realised, there is still much to be learnt in terms of process design, service delivery, skills mix, p ...
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 10

 TERMINÉ 

Addictions and Lifestyles In Contemporary Europe – Reframing Addictions Project (ALICE RAP)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2016,

ALICE RAP is a Europe wide project of 43 partner research institutions involving 107 researchers from 25 European countries providing 1000 months of a plurality of scientific endeavour to analyse the place and challenges of addictions and lifestyles to the cohesion, organization and functioning of contemporary European society. Through integrated multidisciplinary research, a wide range of factors ...
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 46

 TERMINÉ 

Optimisation of treatment with off-patent antimicrobial agents of ventilator-associated pneumonia (VAP) (MagicBullet)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

Background. Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries. Inappropriate empiric antimicrobial treatment is associated with increased mortality. In this context, the empirical treatment of choice for VAP is unknown. Colistin, and “old” dru ...
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 11

 TERMINÉ 

European Network of HIV/AIDS Cohort Studies to Coordinate at European and International Level Clinical Research on HIV/AIDS (EuroCoord)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

Over the past 15 years, EU-funded cohorts and collaborations (EuroSIDA, CASCADE and PENTA), have played a central role in developing our understanding of HIV progression and the effects of ART, enabling European expertise to contribute directly to the advances in patient diagnosis and management worldwide, and providing a continued surveillance mechanism for detection of emerging problems at a Eur ...
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 26

 TERMINÉ 

Adopting Hospital Based Health Technology Assessment in EU (AdHopHTA)

Date du début: 1 sept. 2012, Date de fin: 30 nov. 2015,

The use of HTA as a part of the decision-making process at national, regional, and international levels has evolved considerably over the past 35 years. However, still an important number of good-value innovative HTs never reach clinical practice while, in many instances, others with no significant added value actually do. This situation can be effectively overcome by approaching HTA at hospital l ...
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 11

 TERMINÉ 

Generation of a new class of antiretrovirals targeting HIV-cellular cofactors interactions (HIVINNOV)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2015,

Highly active antiretroviral therapy is effective at controlling HIV-1 replication, however emergence and transmission of drug-resistant viruses is increasing, including viruses resistant to the newly developped integrase catalytic inhibitors. It is essential that new antiretrovirals (ARVs) become available. Most ARVs in development belong to the classes of viral enzyme inhibitors. Since HIV requi ...
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 7

 TERMINÉ 

Virtual Physiological Human: Sharing for Healthcare - A Research Environment (VPH-Share)

Date du début: 1 mars 2011, Date de fin: 31 mai 2015,

VPH-Share will develop the organisational fabric (the infostructure) and integrate the optimised services to (1) expose and share data and knowledge, (2) jointly develop multiscale models for the composition of new VPH workflows, (3) facilitate collaborations within the VPH community. Four flagship workflows (from @neurIST, euHeart, VPHOP, Virolab) provide existing data, tools and models, engage w ...
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 20

 TERMINÉ 

Suicidality: Treatment Occurring in Paediatrics (STOP)

Date du début: 1 nov. 2010, Date de fin: 30 avr. 2015,

The emergence of suicidality in patients receiving drug treatment is of concern because of the overall burden and the possible link with completed suicide. The lack of uniform requirements for defining, detecting and recording suicidality and the presence of disease related confounders create major problems. It is possible that Medication-Related Suicidality (MRS) differs from Psychopathology-Rela ...
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 19

 TERMINÉ 

Paediatric European Risperidone Studies (PERS)

Date du début: 1 mai 2010, Date de fin: 30 avr. 2015,

"Second-generation antipsychotics are increasingly being prescribed to children and adolescents. Their use, however, is mostly off-label, and adequate and sufficient data about efficacy and particular safety are lacking. This proposal focuses on two indications, the use of risperidone in children and adolescents with conduct disorder who are not mentally retarded, and the use of risperidone in ado ...
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 22

 TERMINÉ 

Optimizing delivery of health care interventions (ODHIN)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

ODHIN is a Europe wide project involving research institutions from nine European countries that will help to optimize the delivery of health care interventions by understanding how better to translate the results of clinical research into every day practice. ODHIN will use the implementation of identification and brief intervention (IBI) programmes for hazardous and harmful alcohol consumption (H ...
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 21

 TERMINÉ 

eVV - endoVascularVision: new endoscopic tools for real time vascular assisted vision (ENDO-VV)

Date du début: 1 sept. 2010, Date de fin: 31 août 2014,

"One of the main goals in endoscopic surgery is to improve reproducibility and safety by means of computer assisted systems to improve the surgeon’s vision. The main objective of this Transfer of Knowledge action is to conduct a common research programme leading to the development of new endoscopic assisted vision tools for real time enhanced identification of blood vessels (vascular vision). To t ...
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 4

 TERMINÉ 

Fixed Dose Combination drugs for Secondary Cardiovascular Prevention (FOCUS)

Date du début: 1 juil. 2010, Date de fin: 30 juin 2014,

Cardiovascular diseases (CVD) are the leading cause of death worldwide, and their incidence is increasing sharply in developing countries. Two insufficiently addressed factors contribute to increased morbidity and mortality, threatening the effectiveness of any health system: poor patient adherence to treatment, and limited access to medication in resource-poor countries and regions. To address th ...
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 9

 TERMINÉ 

Euro-BioImaging - Research infrastructure for imaging technologies in biological and biomedical sciences (Euro-BioImaging)

Date du début: 1 déc. 2010, Date de fin: 31 mai 2014,

Euro-BioImaging brings together imaging technologies stretching from basic biological imaging with advanced light microscopy, in vivo molecular imaging of single cells to animal models up to the clinical and epidemiological level of medical imaging of humans and populations. Euro-BioImaging, in close consultation with its stakeholders, will address the imaging requirements of both biological and m ...
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 44

 TERMINÉ 

Coordinating resources to assess and improve health status of migrants from Latin America (COHEMI)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2013,

"European health systems are committed to meeting the challenge of understanding the needs of migrant populations and adapting their services to meet these needs. The difficulties inextricably linked to this challenge are caused by the complexity of migration patterns and the differences between migrant population across EU countries. At present, the limited available data show that attempts to in ...
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 10

 TERMINÉ 

Improving health services for European citizens with dementia: Development of best practice strategies for the transition from ambulatory to institutional long-term care facilities (RightTimePlaceCare)

Date du début: 1 janv. 2010, Date de fin: 30 sept. 2013,

Given the increasing number of patients/consumers with dementia, political action is urgently required to prepare the health care services throughout Europe to deliver cost effective high quality long-term care to people concerned. Currently there is a lack of clinical research data of patients/consumers and informal caregivers to develop best practice strategies for long-term care. RightTimePlace ...
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 8

 TERMINÉ 

European Project on Mendelian Forms of Parkinson’s Disease (MEFOPA)

Date du début: 1 avr. 2010, Date de fin: 30 sept. 2013,

"The Collaborative Project on Mendelian Forms of Parkinson’s Disease (MEFOPA) will bring together the major groups in Europe with a track-record in basic and clinical research on rare Mendelian forms of Parkinson’s disease (PD) in order to identify and validate relevant disease-related molecular pathways, drug-targets and biomarkers for disease susceptibility and progression.. Over the last years ...
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 27

 TERMINÉ 

Identification and validation of novel drug targets in Gram-negative bacteria by global search: a trans-system approach (AntiPathoGN)

Date du début: 1 févr. 2009, Date de fin: 31 juil. 2013,

Multi-drug-resistant bacterial infections are increasing at an alarming pace in both developing and developed countries and in both community and nosocomial settings. The few antimicrobial agents that have been launched during the last decade (e.g. linezolid, daptomycin) have a good activity against Gram-positive bacteria. However, multi-drug-resistant bacteria are often found among the Gram-negat ...
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 11

 TERMINÉ 

Genetic study of Common Hereditary Bowel Cancers in Hispania and the Americas (CHIBCHA)

Date du début: 1 juin 2009, Date de fin: 31 mai 2013,

"Colorectal cancer (CRC) is common in both sexes, has relatively poor outcome and has no major avoidable risk factor. Recent studies have shown that common inherited single nucleotide polymorphisms (SNPs) can increase cancer risk. We have shown CRC risk to be associated with SNPs on chromosomes 8q24.21, 15q14 and 8q21. These variants account for
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 10

 TERMINÉ 

Collaborative European effort to Develop Diabetes Diagnostics (CEED3)

Date du début: 1 déc. 2008, Date de fin: 30 nov. 2012,

"CEED3 (Collaborative European Effort to Develop Diabetes Diagnostics) has as its central objective, the development of diagnostic tools to differentiate specific subgroups of diabetic patients to allow individualisation of patient care. CEED3 will achieve this by integrating basic science findings from animal models, cell studies, and large scale genetic studies with clinical observations and tes ...
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 12

 TERMINÉ 

Plasmodium Vivax Infection in Pregnancy (PREGVAX)

Date du début: 1 mars 2008, Date de fin: 31 août 2012,

"Malaria in pregnancy has been recently prioritised by the EC 7th Framework Program. In response, we propose to carry out a cohort observational study in pregnant women in 5 P. vivax endemic countries, broadly representing most of the world's infections. The Indian and Papua New Guinean endemic sites are included because of their important contribution to the global burden of vivax malaria; PNG h ...
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 9

 TERMINÉ 

NOVEL ULTRASOUND-BASED TRIDIMENSIONAL TOOLS FOR STRUCTURAL AND FUNCTIONAL EVALUATION OF VOLUMES OF INTEREST IN HUMAN ORGANS (uVOLUMES)

Date du début: 1 août 2008, Date de fin: 31 juil. 2012,

One of the main goals in diagnostic medicine is the possibility to obtain not only structural, but also histological and functional information using imaging techniques. The main objective of this Transfer of Knowledge strategy is to conduct a common research programme leading to the development of new tridimensional ultrasound tools for automated analysis of tissue characteristics and perfusion i ...
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 2

 TERMINÉ 

Supporting Healthier and Independent Living for Chronic Patients and Elderly (NEXES)

Date du début: 1 mai 2008, Date de fin: 31 mai 2012,

Description The project aim is to ensure immediate successful deployment of ICT-enabled integrated care programs supporting healthier and independent living.The increasing prevalence of chronic disorders is expected to continue, leading to further dysfunctions of our current healthcare systems. It is widely accepted the importance of intr ...
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 12

 TERMINÉ 

Clinical Continuity by Integrated Care (Homecare)

Date du début: 1 avr. 2009, Date de fin: 31 mars 2012,

Our comprehensive approach to clinical continuity by integrated care (IC) across the secondary-primary interface departs from a preliminary literature review selecting frequent chronic conditions (CC) as stroke, COPD and HF as our focus areas. However, within each of these areas IC is a small activity, still, requiring more basic research. As IC for these different CC are based on the same patient ...
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 13

 TERMINÉ 

European Network of Bipolar Research Expert Centres (ENBREC)

Date du début: 1 juil. 2009, Date de fin: 30 juin 2011,

"Bipolar (BP) disorder is characterized by recurrent manic and depressive episodes, affecting more than 1% of the EU population. Delay in the diagnosis (based only on clinical features), uncertainties in the definition of episodes and on the treatment strategy best adapted to each patient lead to devastating socio-economic, professional and family consequences that be reverted by optimized diagnos ...
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 6

 TERMINÉ 

Reflecting the Positive diveRsities of European prIorities for reSearch and Measurement in end of life cAre (PRISMA)

Date du début: 1 mai 2008, Date de fin: 30 avr. 2011,

"There is little coordination in undertaking research in end of life care. This is due to lack of agreement on what constitutes “end of life” cancer care, no information on public or clinical priorities for achieving a “good death” in a culturally diverse Europe, few appropriate measures of quality, and a lack of established best practice. “PRISMA” aims to deliver an integrated programme to coordi ...
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 11