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TERMINÉ
Defining the Biomechanics of the Developing Heart through High-Speed Dynamic Fluorescent Imaging in Transgenic Quail Embryos (DynImHeart)
Date du début: 1 août 2013, Date de fin: 31 juil. 2015,
Vertebrate heart morphogenesis is a complex process that integrates different structures and cell types compelled to interact by genetic and epigenetic factors. Mistakes at any step from cell-commitment to valve formation will have a major impact on heart morphogenesis leading to congenital heart disease. Avian embryos offer an ideal system to study heart development because the development of th ...
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TERMINÉ
Developing high-thoughput bioassays for human cancers in zebrafish (ZF-CANCER)
Date du début: 1 avr. 2008, Date de fin: 31 mars 2011,
"Recently the zebrafish has emerged as a new important system for cancer research because the zebrafish genome contains all orthologs of human oncogenes and forms tumors with similar histopathological and gene profiling features as human tumors. The zebrafish provides an in vivo vertebrate model for identifying novel mechanisms of cancer progression and for development of new anticancer compounds ...
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