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A systems approach linking genotype and environment to phenotype: oxidative stress response mechanisms in fission yeast (PhenOxiGEn)
Date du début: 1 oct. 2008, Date de fin: 31 mars 2012,
Cellular protection against oxidative damage is relevant to ageing and numerous complex diseases. We plan to use fission yeast as a model organism to gain a systems-level understanding of the oxidative stress response and obtain insights into the interplay of variable genotype, phenotype, and environment. To this end, the four participants will pursue a range of multi-disciplinary and complementin ...
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