Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Towards an evolutionary ecology of spermatogenesis (SPERM EVOLUTION)
Date du début: 1 sept. 2012, Date de fin: 31 mars 2015,
...ng on sperm, spermatogenesis and the testis, and adopt a multidisciplinary approach to test the working hypothesis that post-copulatory sexual selection has been a major force during sperm and testis evolution. Such a research programme is needed, because evolutionary biologists have traditionally treated the testis as a “black box” (ignoring the details of its function) whereas more clinically-or ...
Voir le projet
1
Participant partenaire
TERMINÉ
The role of recombination in evolution and epidemiology of bacterial pathogen Streptococcus pneumoniae (R-evolution pneumo)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2015,
The aim of this project is to improve our understanding of the role of recombination (uptake and incorporation of foreign DNA) for the evolution and epidemiology of the major human bacterial pathogen Streptococcus pneumoniae, also known as the pneumococcus. There is an increasing appreciation of the public health significance of recombination in S. pneumoniae, where recombination has enabled major ...
Voir le projet
2
Participants partenaires
TERMINÉ
European Vascular Interventions and Therapeutic Innovation Network (EVOluTION)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2020,
EVOluTION, a pioneering network within EU in view of its focus on endogenous protective mechanisms, is formed to provide training for 11 young researchers in innovative therapeutic strategies, integrating early detection and prevention, to yield novel approaches to the management of chronic vascular and metabolic diseases that affect the increasing ageing population of Western societies. Fully ali ...
Voir le projet
6
Participants partenaires
TERMINÉ
The origin of evolutionary novelties: regulation of Hoxd genes and the evolutionary transition from fish fins to tetrapod limbs (Limb evolution)
Date du début: 16 févr. 2009, Date de fin: 15 févr. 2011,
The fossil record suggests that fish fins suffered sequential transformations, giving rise to limbs close to the origin of tetrapods. However, the molecular mechanisms that underlie this evolutionary transition remain unclear. Interestingly, Hoxd genes exhibit a single phase of expression during zebrafish fin development but, in contrast, are expressed in two independent phases during mice limb de ...
Voir le projet
2
Participants partenaires
TERMINÉ
The evolution of cancer in ageing societies: An international perspective (CAN-EVOLUTION)
Date du début: 1 mai 2012, Date de fin: 30 avr. 2014,
"This project is a training-through-research project that aims to describe the global evolution of cancer in the ageing societies using international comparison studies. Three theories have been proposed to explain the dynamics of ageing populations: compression of morbidity, expansion of morbidity, and dynamic equilibrium. Yet, these theories have never been applied to understand the evolution of ...
Voir le projet
1
Participant partenaire
TERMINÉ
The role of oxidative stress for the evolution of traits generated by melanins (MELANIN EVOLUTION)
Date du début: 8 oct. 2010, Date de fin: 7 oct. 2012,
...H), which are low during the production of one of the main types of melanin (i.e. eumelanin), but high during the production of the other form (i.e. pheomelanin). Therefore, the current model for the evolution of melanic traits gives a key role to oxidative stress, but it has not been properly tested yet. The project proposed here aims at testing this evolutionary scenario. First, an experiment wi ...
Voir le projet
1
Participant partenaire
TERMINÉ
Dual Fuel Euro6 Engine Conversion Feasibility Study (E6 Evolution)
Date du début: 1 juil. 2015, Date de fin: 31 déc. 2015,
G-Volution has been a pioneer of the use of dual fuel technology in heavy road haulage vehicles in the UK and Europe, with current operators using dual fuel on a daily basis reporting real world CO2 emissions reduction of at least 15%, with consequent reductions in NOx and particulate emissions. The Company has invested heavily in development for more than 8 years, producing a range of patented t ...
Voir le projet
1
Participant partenaire
TERMINÉ
The development and evolution of the mesoderm in basal bilaterian acoel worms (Mesoderm Evolution)
Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,
Understanding the evolution of the diversity of animal forms is one of the major tasks in biology. The use of molecular biology led to a better understanding of how evolutionary changes in the development can result in changes in the body plan. Modifications of the wiring between genes caused the adoption and co-option of gene regulatory networks that shape the morphology of the adult during the d ...
Voir le projet
1
Participant partenaire
TERMINÉ
Evolution in island birds: testing patterns and investigating mechanisms (Evolution on islands)
Date du début: 1 sept. 2008, Date de fin: 30 sept. 2009,
Species on islands are widely believed to undergo similar evolutionary changes as an adaptation to the island environment, a process referred to as the ‘island syndrome’. These changes affect morphological, reproductive, physiological and behavioural traits such as sexual selection. Evolutionary change on islands is believed to relate to genetic (e.g. bottleneck) and ecological factors (e.g. relea ...
Voir le projet
1
Participant partenaire
TERMINÉ
Alta Rezia Evolution Valtellina Valposchiavo Bike
Date du début: 30 sept. 2010, Date de fin: 29 sept. 2013,
The project involves the development and promotion of tourism in the territories of province of Sondrio and the Valposchiavo through the development, promotion and the integration of the offer destined to mountain bikers making the most of cycling environmental and natural features of routes (roads and walking paths mountains, dirt roads, mule trails, military roads). There will be presentati ...
Voir le projet
3
Participants partenaires
TERMINÉ
Tracing the evolution of alpha-proteaobacterial genomes (GENOME EVOLUTION)
Date du début: 1 mars 2008, Date de fin: 28 févr. 2010,
...20 alpha-proteobacterial genomes have been completely sequenced, ranging in size from 1.1 to 9.1 Megabases, and many more will be available in the near future. The aim of this project is to study the evolution of the alpha-proteobacteria by analyzing their genomes, and as such gain insight in how specific alpha-proteobacterial lineages have evolved into the present-day pathogens and (endo)symbiont ...
Voir le projet
1
Participant partenaire
TERMINÉ
Magnetic Resonance of Heterogeneous Matter in Rotating Magnetic Fields: Applications to Living Systems (R-EVOLUTION-M-R)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2014,
...f chemical and biological function. Many systems (e.g. organisms) are however heterogeneous and, currently, studies by high-resolution NMR spectroscopy necessitate fast sample rotation (thousands of revolutions per second) at the so-called “magic angle” with the magnetic field. Practical, scientific and ethical issues are raised when we extrapolate this technique to small animals or even to living ...
Voir le projet
2
Participants partenaires
TERMINÉ
Rassembler les données flore/habitats et conservation dans une base de données liée aux bases bibliographie et iconographie. Échanger des données avec nos partenaires. Diffusion de l'information sur le web. Achievements: Définition de cahiers des charges de solutions in ...
Voir le projet
2
Participants partenaires
TERMINÉ
Bacterial evolution of hypersensitivity and resistance against antimicrobial peptides (resistance evolution)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,
Evolution of resistance towards a single drug simultaneously increases (cross-resistance) or decreases (collateral sensitivity) fitness to multiple other antimicrobial agents. The molecular mechanisms driving cross-resistance are relatively well described, but it remains largely unclear how frequently does genetic adaptation to a single drug increase the sensitivity to others and what the underlyi ...
Voir le projet
1
Participant partenaire
TERMINÉ
Theory and astrophysical applications of neutrino flavor evolution (Neutrino Evolution)
Date du début: 1 août 2009, Date de fin: 31 juil. 2011,
Neutrino flavor oscillations in the astrophysical and cosmological context often require to go beyond the usual amplitude-level treatment that is typical for laboratory applications. Instead, a Boltzmann kinetic equation in terms of matrices of densities in flavor space is required that captures in a consistent way both the effect of oscillations, the refractive effect of a background medium, and ...
Voir le projet
2
Participants partenaires
TERMINÉ
Integrated evolutionary analyses of genetic and drug interaction networks in yeast (network evolution)
Date du début: 1 juil. 2008, Date de fin: 30 juin 2013,
The ability of cellular systems to adapt to genetic and environmental perturbations is a fundamental but poorly understood process both at the molecular and evolutionary level. There are both physiological and evolutionary reasonings why mutations often have limited impact on cellular growth. First, perturbations that hit one target often have no effect on the overall performance of a complex syst ...
Voir le projet
1
Participant partenaire
TERMINÉ
The project is a cooperation between the University Hospitals in Copenhagen and Lund and in this pre-project the aim is to discuss the possiblities of creating a centre for clinical competence in the Oresund Region. The centre should have international status as well as regional status and deal with different aspects of clinical competence, such as simulator training on clinical competence and the ...
Voir le projet
2
Participants partenaires
TERMINÉ
Avian brain evolution and higher level phylogenetics of modern birds (AVIAN EVOLUTION)
Date du début: 8 nov. 2010, Date de fin: 7 oct. 2012,
"The evolution of modern birds is still poorly understood. My recent phylogenetic results constitute the first step towards a new picture of the history of modern birds and demonstrate that the incorporation of key fossil taxa into phylogenetic analyses permits to elucidate hypotheses of relationship supported on the basis of extant taxa alone. Milner and colleagues recently investigated the brain ...
Voir le projet
1
Participant partenaire
TERMINÉ
Intracellular protein aggregation: fitness and evolution (Fitness & Evolution)
Date du début: 1 sept. 2012, Date de fin: 31 août 2014,
...aneously, a specific DNA tag informs about the proportion of each strain in the culture at each time point. By this we will evaluate how protein aggregation influences cell fitness, thus deriving evolutionary principles underlying intracellular regulation of protein deposition.
Voir le projet
1
Participant partenaire
TERMINÉ
Rough surfaces in sliding contact: A combined atomistic/continuum investigation of topography evolution (Topography Evolution)
Date du début: 1 mai 2011, Date de fin: 30 avr. 2014,
...th respect to each other. Energy efficient devices need interfaces that are tailored to consume little to no energy. This requires a fundamental understanding of frictional dissipation processes. The evolution of the topography of the two surfaces that are in contact is a crucial component of sliding friction: Processes such as fracture and plastic flow dissipate energy and contribute to the macro ...
Voir le projet
2
Participants partenaires
TERMINÉ
The evolutionary genetics of virulence: host-pathogen interactions in Daphnia magna (Virulence Evolution)
Date du début: 1 juin 2010, Date de fin: 31 mai 2012,
...ion or to minimise the virulence of disease once a pathogen has invaded. Accordingly, understanding the mechanisms behind the defence against infection and virulence has been a major goal of not only evolutionary biologists interested in host-pathogen interactions, but also epidemiologists involved in public health considerations and agriculturalists attempting to minimise the impact of pests. How ...
Voir le projet
2
Participants partenaires
TERMINÉ
Objectifs : Cette étude doit favoriser la cohérence des projets transfrontaliers, sur les axes principaux et montrer les perspectives pour lirrigation de lespace frontalier et pour la promotion de celui-ci dans lespace européen. Actions : Létude consiste : - a établir létat actuel de la mobilité dans la zone dinfluence des axes routiers jurassiens ; - a évaluer les perspectives dévolution a moyen ...
Voir le projet
1
Participant partenaire
TERMINÉ
The Electric Vehicle revOLUTION enabled by advanced materials highly hybridized into lightweight components for easy integration and dismantling providing a reduced life cycle cost logic (EVOLUTION)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
...d by an all-electric power-train (FEV). Neither approach address lightweight or modularity inheriting the same disadvantages as conventional ICEV - Electrification of mobility must face a conceptual rEVOLUTION! This project breaks the paradigm of current Body-in-White (BiW) by delegating the whole structural function to a novel BiW archetype made up of a central cell, including Multifunctional-Rol ...
Voir le projet
25
Participants partenaires
TERMINÉ
Investigation of shape evolution in neutron-rich nuclei using gamma-ray spectroscopy techniques (Shape Evolution)
Date du début: 3 oct. 2016, Date de fin: 2 oct. 2018,
...osed to model the complex strong interaction between the neutrons and protons in a nucleus, however, a thorough understanding of its quantum structure is still far from being complete. Studies of the evolution of nuclear structure in mass regions away from the valley of stability have revealed dramatic modifications of the ordering of single-particle orbitals in exotic nuclei as compared to the on ...
Voir le projet
1
Participant partenaire
TERMINÉ
Principles of dialect evolution in killer whales (Dialect evolution)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2015,
Dialects occur in a range of species, from human language to bird song. This project will focus on dialect evolution in killer whales. Each pod of killer whales shares a unique repertoire of discrete calls – a vocal dialect, which passes from mother to offspring through social learning. It is commonly accepted that killer whale dialects change gradually with time by accumulation of stochastic copy ...
Voir le projet
1
Participant partenaire
TERMINÉ
The evolution of immune defences in avian brood parasites and their hosts (HONEYGUIDEIMMUNITY)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2015,
...hosts that might raise them. Honeyguides also destroy host eggs and kill host chicks which remain rotting in the nest, further exposing parasite nestlings to high disease pressure. I will ask if over evolutionary time this has selected for strong immune defences and if Honeyguides suffer less than host nestlings in terms of reduced growth when disease conditions are experimentally altered. Using a ...
Voir le projet
1
Participant partenaire
TERMINÉ
The Ecology and Evolution of Mimicry in a Changing World (EcoEvoMimic)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2016,
...s are economically-important pollinators, and both are currently in decline across much of their ranges. The applicant will establish the ecological responses to climate change in these taxa, and the evolutionary consequences of those responses. The project will provide novel experimental tests for hypotheses that explain the evolution of mimicry across a range of taxa. The project comprises a set ...
Voir le projet
1
Participant partenaire
TERMINÉ
Compétences de l'encadrement intermédiaire dans les entreprises du bâtiment en Europe: adaptation des parcours de formation à l'évolution des besoins
Date du début: 1 sept. 2015, Date de fin: 31 août 2018,
The ConstructyVET project is aimed at devising a transnational action plan for the development of middle management skills on building sites. The partners want to narrow the gap between the expectations of companies with regard to knowledge, skills and competences on the one hand and the qualifications of the workforce immediately after training on the other. Indeed, on completion of current train ...
Voir le projet
9
Participants partenaires
TERMINÉ
Probing Star Formation and Galaxy Evolution with Gamma-Ray Bursts (GRB)
Date du début: 1 oct. 2008, Date de fin: 30 sept. 2011,
.... The main objectives are: (1) Determine the ionisation history of the Universe and characterise the sources that drive it. The luminosity of GRB afterglows offers a unique opportunity to measure the evolution of the intergalactic medium out to very high redshift. High-redshift GRBs (z > 6) will be discovered via rapid optical/NIR observations, thus enabling subsequent prompt spectroscopy to obtai ...
Voir le projet
1
Participant partenaire
TERMINÉ
Production and Analysis Evolution For Lattice Related Barrel Elements Under Operations With Advanced Robustness (POLARBEAR)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2016,
The PoLaRBEAR (Production and Analysis Evolution For Lattice Related Barrel Elements Under Operations With Advanced Robustness) project focuses on reliable novel composite aircraft structures based on geodesic technology aiming at a significant higher Robustness and Technology Readiness Level (TRL).While the global structural behavior of composite geodesic structures is investigated and understood ...
Voir le projet
13
Participants partenaires
TERMINÉ
Directed evolution of ketoreductases in gel-shell beads (KREDs in GSBs)
Date du début: 1 juin 2015, Date de fin: 31 mai 2017,
...equired in the manufacture of many pharmaceutical products. Ketoreductases (KREDs) capable of reduction of ketones to the corresponding secondary alcohol have been improved through classical directed evolution campaigns but a limiting factor has always been the challenge of matching selection conditions to the final scaled-up reaction. Here we propose a solution to that problem. The Host group pr ...
Voir le projet
1
Participant partenaire
TERMINÉ
Evolution of olfactory circuits (EVONEURO)
Date du début: 1 juin 2014, Date de fin: 31 mai 2019,
...vous systems have undergone remarkable diversification in their structure and function as animals have adapted to distinct ecological niches. What are the genetic mechanisms underlying neural circuit evolution? The project addresses this fundamental question in the Drosophila olfactory system, a superior ""evo-neuro"" model for several reasons: (i) as in mammals, the Drosophila olfactory system ha ...
Voir le projet
1
Participant partenaire
TERMINÉ
Stellar HYdrodynamics Nucleosynthesis and Evolution (SHYNE)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
...-physics, applied mathematics and computer science. Unfortunately stars cannot be modelled fully in 3D. The best way to model them is to develop synergy between 3D and 1D models to improve 1D stellar evolution models.This programme will tackle this multi-disciplinary challenge, which is out of reach of individual research groups. For this purpose, my team, with the help of a network of world leadi ...
Voir le projet
1
Participant partenaire
TERMINÉ
Evolution of Regulatory Landscapes in Chordates (EVOREL)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2017,
Evolution of animal forms largely depends on changes in developmental gene expression patterns. These genes are controlled by a large number of cis-regulatory elements (CREs) distributed in extended genomic regions organized in 3D chromatin structures known as regulatory landscapes (RLs). However, it is currently unknown how these RLs originate and evolve and how changes in RL architecture and ass ...
Voir le projet
1
Participant partenaire
TERMINÉ
Directed evolution and semi-rational engineering of plant cell wall-degrading enzymes (DegradePlant)
Date du début: 1 juin 2011, Date de fin: 31 mai 2013,
This proposal focuses on the development of new techniques and strategies for the directed evolution of enzymes useful for industrial (white) biotechnology, including the development of new genetic methodologies to improve the potential of variant libraries, as well as new screening tools to broaden the range of targets for directed evolution. Specifically, the proposed project will apply these ne ...
Voir le projet
1
Participant partenaire
TERMINÉ
Network Analysis of Musculoskeletal Evolution and Modularity during the Fin-to-Limb Transition (LIMB NETWORKS)
Date du début: 15 août 2015, Date de fin: 14 août 2018,
The fin-to-limb transition was a major milestone in the history of life that shaped the morphology and remarkable biodiversity of land vertebrates. A central question in vertebrate evolution is how the various anatomical parts of limbs evolved semi-autonomously (modularity) while still growing and adapting in coordination (integration). The main goal of this project is to unravel (i) the evolution ...
Voir le projet
1
Participant partenaire
TERMINÉ
Evolution Meets MAcroecology - integrating rapid adaptation into predictions of future plant species' ranges (EMMA)
Date du début: 1 juin 2010, Date de fin: 31 mai 2012,
...rs. However, the reliability of recent model-based assessments for future species' range dynamics suffers from the fact that most macroecological modeling approaches lack in ecological mechanisms and evolutionary dynamics. The present project seeks to improve the quality and reliability of species distribution models by bridging the gap between macroecological approaches and the accumulating evide ...
Voir le projet
2
Participants partenaires
TERMINÉ
Contradictory phenotypic and genetic sex can lead to great insights into sex chromosome evolution (NEW SEX SAME GENES)
Date du début: 1 juil. 2010, Date de fin: 30 juin 2012,
"For the first time the possibility to change certain species sex while maintaining their original sex chromosomes is presented as an excellent opportunity to unravel aspects of sex chromosome evolution. Theory of sex chromosome evolution states that sexually antagonistic genes, i.e. genes that are beneficial to one sex but at the same time harmful to the opposite sex, should often be linked to on ...
Voir le projet
1
Participant partenaire
TERMINÉ
New enzymes by identification from metagenomic libraries and directed evolution using microfluidic microdroplets (MetaPromis)
Date du début: 1 juin 2010, Date de fin: 31 mai 2012,
...olved proteins that fit into the catalytic task to some extent (a phenomenon known as catalytic promiscuity) and improve their catalytic performance for the desired reaction by directed protein evolution techniques. In order to reach this strategic goal, we aim to employ a new high throughput technology (in vitro compartmentalization in microfluidic water-in-oil emulsion droplets) in the search fo ...
Voir le projet
1
Participant partenaire
TERMINÉ
Evolution of flower morphology: the selfing syndrome in Capsella (CAPSEVO)
Date du début: 1 déc. 2010, Date de fin: 30 nov. 2016,
"The change from reproduction by outbreeding to selfing is one of the most frequent evolutionary transitions in plants. This transition is generally accompanied by changes in flower morphology and function, termed the selfing syndrome, including a reduction in flower size and a more closed flower structure. While the loss of self-incompatibility is relatively well understood, little is known about ...
Voir le projet