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 TERMINÉ 

Directed Protein Evolution for Synthetic Biology and Biocatalysis (ES-Cat)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2021,

ES-Cat will use directed evolution as a tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes – that perform at levels near perfection. Instead of seeing rational and combinatorial approaches as alternatives, we combine them in this network to achieve a ‘smarter’ and more efficient exploration of protein sequence space. By harnessing the forces of Dar ...
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 TERMINÉ 

Synthetic bacterial lipid rafts to optimize industrial bioprocesses (Rafts4Biotech)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Genetic tractability of bacterial cells allows generating synthetic microbial chassis platforms (SMCPs) with remarkable biotechnological applications but their functionality currently faces important off-genome limitations due to deficient protein-protein interactions, unfavorable protein stoichiometry or generation of toxic intermediates that ultimately compromise the industrial production proces ...
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 13

 TERMINÉ 
Two academic groups and eight SMEs who all work on different aspects of protein engineering will collaborate and produce a website that will consist of a portal with an embedded workbench to provide users a self-service system for in silico protein engineering. This interactive self-service portal will give users access to a wide variety of protein engineering facilities and information systems, a ...
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 10

 TERMINÉ 
Our business concept focuses on development and marketing of stable fibroblast growth factors (FGFs) for medical, personal care and research use. FGFs are currently being tested therapeutically for use in cancer treatment, regenerative medicine, as well as in cosmetics. The FGF-based therapeutic approaches contribute towards promoting active and healthy ageing, which is a societal challenge common ...
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