3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Exploiting the power of human induced pluripotent stem cells to generate synthetic retinae in vitro for cell based therapies, drug discovery and disease modelling (RET-iPSC)
Date du début: 1 juin 2014, Date de fin: 31 mai 2018,
Blindness represents an increasing global problem with social and economic impacts both for the patients and society in general. Recent estimates indicate that the overall number of people with visual loss is 285 million globally, of whom 39 million are blind. In Europe, approximately 1 in 30 individuals experience sight loss and 75% of those are unemployed, a social burden which is anticipated t ...
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TERMINÉ
Using evolution to uncover the importance of alternative pre mRNA splicing (ConserveAS)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,
A major mystery of the genome age is why complex and simple organisms all have a similar number of genes. My specialism is in ‘Alternative Splicing’ which is the means by which different products can be made from a single gene by differential incorporation of regions of pre-mRNA. Alternative splicing is therefore a mechanism to increase gene complexity in complex organisms like man and in complex ...
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TERMINÉ
Assembly and coordination of peptidoglycan synthesis complexes during bacterial growth and cell division (PGRECONST)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2016,
In this project, I will investigate the proteins involved, and their interactions, in the formation of both peptidoglycan (PG) synthesis core complexes (elongasome and septosome) in the model bacterium Escherichia coli to gain new molecular insights into how the cell grows its cell wall during the cell cycle. This will be achieved by: (i) in vivo characterization of new or already known important ...
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