Date du début: 1 nov. 2011,
Date de fin: 31 oct. 2016,
One of the most significant challenges facing science and society is how to promote lasting changes in people’s behaviour. What kinds of interventions influence the behaviours that lead to obesity or persuade people to use less energy in their homes? The present proposal argues that one reason that people struggle to change is that they fail to monitor the relation between their current behaviour ...
Date du début: 1 avr. 2009,
Date de fin: 31 mars 2014,
Recent advances in biology, neuro-imaging, the observation of space by satellites, and many other disciplines has lead to an explosion of data and it is now absolutely imperative that a theoretical framework is developed that can be used to analyse this data to identify system dynamic behaviours in a transparent manner to reveal core dynamic behaviours and features. Complex nonlinear behaviours ar ...
Date du début: 1 janv. 2011,
Date de fin: 31 déc. 2012,
Flap endonuclease 1 (FEN1) catalyzes the removal of 5’-flap structures generated by strand-displacement synthesis during lagging-strand DNA synthesis and long-patch base excision repair. Homozygous knockout of FEN1 in mice is embryonically lethal, whereas haploinsufficiency or catalytic deficiency due to mutation leads to rapid tumor progression, thereby illustrating the importance of FEN1 to geno ...
Date du début: 1 janv. 2008,
Date de fin: 30 juin 2012,
BIOTACT will develop novel biomimetic computational methods and technologies for active touch sensing. The project is inspired by the functionality, morphology, and neural processing architectures of biological sensory systems that use tactile hairs known as whiskers or vibrissae. It will focus on two animals that are tactile specialists--the Norwegian rat and the Etruscan shrew. Both species make ...
Date du début: 1 sept. 2009,
Date de fin: 31 déc. 2011,
"FUTURAGE aims to produce the definitive road map that will guide European research on ageing and health for the next 10-15 years. It represents plans for the most extensive consultation ever conducted in this field and for the mobilisation of not only the leading scientists but also the stakeholders that will determine the fate of the road map. FUTURAGE combines all of the major coordination acti ...
Date du début: 1 sept. 2008,
Date de fin: 31 août 2010,
Human embryonic stem cells (hESC) are pluripotent cells derived from blastocyst stage early embryos. Since the original publication a vast number of studies have described the differentiation of hESC and their potential in regenerative medicine. It is now well known that hESC might be used in cell replacement therapies in a number of severe degenrative diseases like Type I diabetes or Parkinson’s ...
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