Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Setting up an Italian-Slovenian Service Centre to carry out the collection, analysis, qualitative assessment and marketing of milk (produced by cows, goats or sheep) and its subsequent processing with innovative company-supporting technologies . (CIS)
Date du début: 28 févr. 2006, Date de fin: 29 sept. 2008,
The constant development of cattle, goat and sheep breeding in the cross-border area makes it possible to maintain the rural culture and the population in the area. Livestock farms therefore become very important from the social point of view, for they ensure the continuity of traditional culture in these areas, which are still closely connected with agricultural production. Sheep and goat breedin ...
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1
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TERMINÉ
The development of manganese-based alkene epoxidation, cis-dihydroxylation and alkane C-H oxidation catalysts (MANGANOXI)
Date du début: 1 sept. 2015, Date de fin: 31 août 2017,
The catalytic oxidation of alkenes to give epoxides and syn-diols, as well as the hydroxylation of C-H bonds in alkanes using environmentally benign reagents and conditions remains an area of significant challenge in contemporary synthetic chemistry and highly effective catalytic systems remains elusive. In the “MANGANOXI’ project a novel and ecologically friendly approach towards the development ...
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1
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TERMINÉ
Cis-regulatory logic of the transcriptional control in neural stem cells (CISSTEM)
Date du début: 1 oct. 2008, Date de fin: 31 mars 2012,
... neurodegenerative diseases. It is thus crucial to understand NSCs from as many as possible angles (e. g. cellular and molecular biology), in order to better isolate and successfully manipulate them. CISSTEM presents a post-genomic systems biology approach, taking advantage of new computational and experimental tools to address the specification and maintenance of NSCs at the transcriptional/epige ...
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9
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TERMINÉ
Health in Times of Transition: Trends in Population Health and Health Policies in CIS Countries (HITT-2008)
Date du début: 1 mai 2009, Date de fin: 30 avr. 2013,
...omic transitions, with a focus on lifestyle-related issues. Overviews: A unique team with extensive expertise in health effects of transition will generate new knowledge on health determinants in 11 CIS countries: Russia, Belarus, Ukraine, Moldova, Kazakhstan, Uzbekistan, Kyrgyzstan, Armenia, Azerbaijan and Georgia. It employs a model of health determinants acting at individual and societal leve ...
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13
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TERMINÉ
Dynamic and evolution of cis-regulatory elements involved in fruit development in Arabidopsis and Brassica (DEHICIS)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2011,
...pment between Arabidopsis and Brassica, and how further changes could be used to limit pod-shattering in Brassica. We will compare the regulatory sequences of these genes in different species, define cis-elements that mediate the interactions within this regulatory network, test the functional significance of these cis-elements in transgenic plants, then use TILLING to screen for regulatory change ...
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1
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TERMINÉ
Identification and Characterization of Cis-Regulatory ModuleDysfunction in Rett Syndrome with ROQ-WACh (ROQ-WACh)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2018,
Precise regulation of gene expression is achieved through the coordinated action of genomic cis-regulatory modules (CRMs). The identification of CRMs has long been a goal of functional genomics as CRM dysregulation can have devastating consequences for health and development such as autism. For example, mutations in the MeCP2 gene, which encodes protein that binds methylated DNA and regulates gene ...
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1
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TERMINÉ
Using cis-regulatory mutations to highlight polygenic adaptation in natural plant systems (AdaptoSCOPE)
Date du début: 1 sept. 2015, Date de fin: 31 août 2020,
...e that novel aspects of the molecular basis of Darwinian adaptation can be discovered if the polygenic basis of adaptation is taken into account. This project will use the genome-wide distribution of cis-regulatory variants to discover the molecular pathways that are optimized during adaptation via accumulation of small effect mutations. Current approaches include scans for outlier genes with stro ...
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1
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TERMINÉ
"The comparative analysis of the economic aspects of international migration: EU, Mediterranean, and CIS" (MIGMEDCIS)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2014,
"The overall objective of the project is to bring together an international and interdisciplinary research teams for the purpose of forming a center for research and transfer of knowledge in the area of international migration.Migration is an international phenomenon that transcends national boundaries. It is no longer limited to only few areas of the world, with many new migration systems having ...
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2
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TERMINÉ
Cis-regulatory variation: Using natural genetic variation to dissect cis-regulatory control of embryonic development (CISREGVAR)
Date du début: 1 sept. 2013, Date de fin: 31 août 2018,
Embryonic development is very robust: In the midst of segregating mutations and fluctuating environments, a fertilized egg has the remarkable capacity to give rise to a precisely patterned embryo. The stereotypic progression of development is driven by tightly regulated programs of gene expression. However, this deterministic view from genetics is at odds with an emerging view of transcription fro ...
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1
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TERMINÉ
Identifying and understanding the cis-regulatory modules that control the spatio-temporal transcription of genes in chordates (CISREGLOGIC)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2013,
A major challenge in deciphering the genome is to understand the genomic sequences which control the spatio-temporal expression of genes. Despite much progress, the rules by which these regions, the cis-regulatory modules (CRMs), control the transcription of a gene remain unclear. The objectives of this proposal are to develop an algorithm to detect novel CRMs, to analyze the identified CRMs, and ...
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1
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TERMINÉ
Study of cis/trans proline isomerization as a novel regulatory mechanism of protein function (ProProteinRegulation)
Date du début: 1 sept. 2012, Date de fin: 31 août 2016,
...ated through wide and complex signaling networks that require a tight spatial and temporal control over protein function. Recently a growing body of evidence has emerged supporting the role of prolyl cis-trans isomerization as a new intrinsic molecular regulatory mechanism with important consequences for protein function. Proline is the only amino acid in proteins that depending on the value of th ...
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2
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TERMINÉ
Improvement of the habitats of CIS through restoration and/or transformation of electrical plants existing and under construction in the Po Delta Park (Po ENEL)
Date du début: 1 juil. 2001, Date de fin: 31 déc. 2006,
Background
The Po Delta Regional Park in central Italy hosts 27 species of nesting birds on Annex I of the Birds Directive and a further 23 species listed in the Annex either winter in the area or migrate through it. As such, the Park is one of Italyâs most important wetland areas but the conservation status of important bird species has been threatened ...
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2
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TERMINÉ
CHARACTERIZATION OF THE B-CELL-SPECIFIC GENE REGULATORY NETWORK BY GENOME-WIDE IDENTIFICATION OF DIRECT PAX5 TARGET GENES (PAX5TARGETS)
Date du début: 1 mars 2008, Date de fin: 28 févr. 2010,
...matin precipitation and Solexa 1G ultrahigh-throughput DNA sequencing. Islands of chromatin modifications have been shown to provide an efficient way of identifying active and repressed promoters and cis-regulatory elements. Here we propose to use chromatin immunoprecipitation (ChIP)-sequencing to map the entire mouse genome for Pax5-controlled promoters and cis-regulatory elements. Integration of ...
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1
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TERMINÉ
European Control System Security Incident Analysis Network (ECOSSIAN)
Date du début: 1 juin 2014, Date de fin: 31 mai 2017,
The protection of critical infrastructures increasingly demands solutions which support incident detection and management at the levels of individual CI, across CIs which are depending on each other, and across borders. An approach is required which really integrates functionalities across all these levels. Cooperation of privately operated CIs and public bodies (governments and EU) is difficult b ...
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22
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TERMINÉ
Derived and Ancestral RNAs: Comparative Genomics and Evolution of ncRNAs (DARCGENs)
Date du début: 1 mai 2010, Date de fin: 30 avr. 2015,
...mmediately provide a new perspective on how these loci arise, evolve and function, including whether their orthologues are apparent across diverse species. Using new evidence that lincRNA loci act in cis with neighbouring protein-coding loci, we will determine lincRNA mechanisms and will establish the consequences of lincRNA knock-down, knock-out and over-expression in mouse, chick and fruitfly.
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2
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TERMINÉ
Epigenetic regulation and monoallelic gene expression: the X-inactivation paradigm and beyond (EpigenetiX)
Date du début: 1 mai 2010, Date de fin: 31 oct. 2015,
...e initiation of XCI is the X-inactivation centre (Xic). The Xic ensures the induction and monoallelic expression of a non-coding RNA (Xist) that is responsible for triggering chromosomal silencing in cis during development. We would like to understand the mechanisms underlying the Xic's functions and define whether other, Xic-like loci exist in the genome. Once XCI is established, the inactive sta ...
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1
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TERMINÉ
Exploring the potential for agricultural and biomass trade in the Commonwealth of Independent States (AGRICISTRADE)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,
...012 and the establishment of a Customs Union between Russia, Belarus and Kazakhstan in 2011 are expected to boost trade relations between the European Union and its Eastern Neighbours. The aim of AGRICISTRADE is to accompany these developments by analysing the potential impact of these trade agreements and by delivering insights on the potential developments of the food, feed and biomass sectors i ...
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17
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TERMINÉ
Analysis of evolutionary conserved signalling pathways mediating polar leaf development in dicotyledonous plants (EvoSignal)
Date du début: 1 juin 2010, Date de fin: 31 mai 2014,
...olutionary conserved signaling modules as well as to define unique signaling pathways. These investigations will be complemented by protein evolution studies of the master regulators and by analyzing cis-element evolution of the target genes they control. The identification of conserved and unique signaling pathways in a diverse range of species will further our understanding of how the three-dime ...
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1
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TERMINÉ
Regulation of the expression of odorant receptor genes in mouse (ORGENECHOICE)
Date du début: 1 avr. 2010, Date de fin: 31 mars 2015,
...a fundamental role in OR gene choice, rather than in transcription after it is chosen for expression; and that the H and P elements are two of several similar regulatory elements that each operate in cis within a cluster. The approach is based on gene targeting and transgenesis by pronuclear injection. A multipronged strategy will be taken to assay OR gene expression, with βgal-reporter mice, in s ...
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2
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TERMINÉ
Mammalian Origin of replication – Genome-wide Mapping and Regulation (Originome)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2016,
...will put me in an excellent position for studying the regulation of the replication machinery. I am planning to combine bioinformatics, comparative genomics and reverse genetics tools to decipher the cis-acting elements that participate in the regulation of the replication program. Successful mapping of origins and characterization of their mode of regulation have broad implications not only in th ...
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1
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TERMINÉ
FUNCTIONS OF CHROMATIN MARKS IN REGULATION OF GENE EXPRESSION (FAME)
Date du début: 1 mars 2013, Date de fin: 29 févr. 2016,
... distribution of histone modifications revealed a complex epigenetic landscape on eukaryotic chromosomes. In particular, distinct chromatin signatures were recently associated with enhancer elements, cis-acting DNA sequences inducing transcription from target promoters. However, whether the deposition of specific marks at enhancers is a pre-requisite for their activity or a mere consequence of the ...
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1
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TERMINÉ
Integrated Promotion of Tourism Opportunities and Cultural-Historic Heritage of Lviv Region, Podkarpackie and Lublin Voivodeships. (IPBU.03.02.00-76-820/12)
Date du début: 31 déc. 2013, Date de fin: 30 déc. 2015,
...eo film on DVD about tourism and recreational opportunities of Lviv Oblast, Podkarpackie and Lublin Voivodivships;5. Tourist info-tour for journalists from EU and CIS to promote Lviv Oblast, Podkarpackie and Lublin Voivodivships.Practical results and indicators of the Micro-project 3.1. To hold information campaign on the micro-project and the Program (2 press conferences, Min. 40 press releases t ...
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12
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TERMINÉ
Optical and Acousto-optic Sensor Technology for Railway-Applications (OpticTrainDetection)
Date du début: 1 oct. 2014, Date de fin: 31 mars 2015,
...016.The commercial exploitation of the development will be ensured by a worldwide presence of Frauscher Sensortechnik GmbH (Headquarter in Austria) in the form of subsidiaries (Poland, India, Brasil, CIS, UK). With the new technology a continuous growth of the company will be possible. A total market volume of 14 billion EUR in the area of signalling and safety infrastructure on railways is an att ...
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1
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TERMINÉ
Evolution of Regulatory Landscapes in Chordates (EVOREL)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2017,
Evolution of animal forms largely depends on changes in developmental gene expression patterns. These genes are controlled by a large number of cis-regulatory elements (CREs) distributed in extended genomic regions organized in 3D chromatin structures known as regulatory landscapes (RLs). However, it is currently unknown how these RLs originate and evolve and how changes in RL architecture and ass ...
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1
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TERMINÉ
Genomics of Chromosome Architecture and Dynamics in Single Cells (GoCADiSC)
Date du début: 1 mars 2017, Date de fin: 28 févr. 2022,
...and with substantially enhanced genomic and temporal resolution; (2) Elucidate the dynamics and diversity of chromosome architecture in single cells, including differentiating cells; (3) Identify cis-determinants of chromosome - landmark interactions through systematic perturbation of linear chromosome organization, both by targeted mutagenesis and by a random scrambling approach; (4) elucidate th ...
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1
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TERMINÉ
Wooden Houses to Russia (Investments)
Date du début: 30 avr. 2002, Date de fin: 30 déc. 2004,
... to Russia contributed to the employment of the others. The companies did, however, feel that it would have been necessary to be active in a larger area in Russia, at least in Moscow, and possibly in CIS countries, where there may be potential markets for wooden houses. A follow-up project of a similar nature was also desired, but with a wider scope than the Interreg III A Karelia area. A need was ...
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3
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TERMINÉ
Molecular mechanisms of mature B cell lymphomagenesis (BCLYM)
Date du début: 1 déc. 2008, Date de fin: 30 nov. 2014,
...e translocations that usually involve the immunoglobulin loci and a proto-oncogene. As a result of the translocation event the proto-oncogene becomes deregulated under the influence of immunoglobulin cis sequences thus playing an important role in the etiology of the disease. Upon antigen encounter mature B cells engage in the germinal center reaction, a complex differentiation program of critical ...
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2
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TERMINÉ
International marketing of a transit route to/from Russia and the CIS countries via South-East Finland, including logistic value added services, with Russia and the CIS countries as an area of focus.
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1
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TERMINÉ
Purification and Characterization of Regulatory Proteins of the Alcohol Oxidase 1 (AOX1) Promoter of Pichia pastoris (AOX1 promoter)
Date du début: 1 sept. 2010, Date de fin: 31 août 2014,
...ze the regulatory proteins that bind to the AOX1 promoter and 2) overexpress his-tagged Methanol Expression Regulator 1 (Mrx1) protein to determine binding sites on the AOX1 promoter 3) determine the cis-acting regulatory sequences and design synthetic promoters. In addition, I will generate new host strains in which activator protein(s) will be over-expressed and expression of the repressor prote ...
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1
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TERMINÉ
Corridor 24 Development Rotterdam-Genoa (CODE24)
Date du début: 8 oct. 2008, Date de fin: 30 déc. 2014,
...ilities, areas requiring strategic spatial development actions or environmental interventions:- A Corridor Info System providing the missing spatial and temporal overviews was set up: code24.ethz.ch/cis/- A test planning procedure was carried out in the Wesel area, to survey the different development options and verify their feasibility.- Collaborative assessments of 3 alternative development scen ...
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17
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TERMINÉ
Coherent control and molecular dynamics in the era of terahertz (COSMODET)
Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,
...mented for studying fragile samples such as bio-molecules. The dipole-selectivity of the THz field will be used for probing dynamic processes involving changes in the molecular dipole (such as transcis isomerization in azobenzene). The broadband resonant interaction of THz with the multilevel rotational system reveals collective light-matter phenomena that are fundamental to spectroscopy and will ...
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1
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TERMINÉ
Sustainable Technologies for Calcined Industrial Minerals in Europe (STOICISM)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
...ect employment to some 42,500 people. A secure supply of sustainable mineral products is essential to maintaining the European mining, mineral and manufacturing industries.The main objective of STOCISM is to enhance the competitiveness of the European industrial minerals industry by developing cleaner, more energy efficient extraction and processing technologies. STOICISM is an industry-led proj ...
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17
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TERMINÉ
Recombination in Adaptive Evolution (EvolRecombAdapt)
Date du début: 1 août 2014, Date de fin: 31 juil. 2019,
...enomics with cutting-edge molecular biology and transgenics. We will 1) create kilobase-scale maps of the recombination landscape in adaptively diverging populations; 2) genetically dissect factors cis- and trans-acting factors that cause recombination variation; 3) characterize molecular mechanisms of recombination modifiers using cutting-edge techniques; and 4) test evolutionary theory that pred ...
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1
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TERMINÉ
How do low frequency acoustic cues improve speech recognition and music appreciation for cochlear implant users? (LFAA)
Date du début: 1 déc. 2010, Date de fin: 30 nov. 2013,
...ores hearing in deaf people by electrically stimulating the auditory nerve. It is the most successful neural prosthesis ever developed. Routine cochlear implantation began in the 1970s and since then CIs have helped restore hearing in over 120,000 deaf people world wide. When CIs were first commercialized the advantages of having a CI were limited and speech recognition after implantation was ofte ...
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1
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TERMINÉ
The origin of evolutionary novelties: regulation of Hoxd genes and the evolutionary transition from fish fins to tetrapod limbs (Limb evolution)
Date du début: 16 févr. 2009, Date de fin: 15 févr. 2011,
...tivated by enhancer elements upstream of the HoxD cluster. This suggests that acquisition of transcriptional regulators of 5’ Hoxd genes may explain the origin of digits in the tetrapod lineage (“cis” evolution hypothesis). Alternatively, these structures may have developed due to recruitment of new binding factors that acted on pre-existent 5’ Hoxd gene enhancers giving rise to a second phase of ...
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2
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TERMINÉ
Producers' Workshop Baltic Bridge East by West
Date du début: 1 sept. 2014, Date de fin: 30 juin 2015,
...ovement of skills and competences of audiovisual professionals and the development of networks by bringing together two groups of film producers-- one from the European Union and the other from the CIS countries, Georgia and Ukraine, each with a project and a view of co-producing with the other region respectively, and four participants without projects-- to exchange information, training, and mar ...
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1
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TERMINÉ
Conservation and Divergence of Tissue-Specific Transcriptional Regulation (ConservRegCircuitry)
Date du début: 1 oct. 2008, Date de fin: 30 sept. 2013,
...anscriptional profile, chromatin state, and complete genomic occupancy of a set of tissue-specific transcription factors in hepatocytes of strategically chosen mammals; (2) to further identify the precise mechanistic contribution of cis and trans effects, we are comparing transcription factor binding at homologous regions of human and mouse DNA in a mouse line that carries human chromosome 21. Tog ...
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2
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TERMINÉ
The mechanism by which cohesin controls gene expression (COHESIN CONTROL)
Date du début: 1 mai 2012, Date de fin: 30 avr. 2017,
...icity is poorly understood due to ignorance of the molecular mechanisms regulating gene expression. Each gene is regulated by a unique set of factors and as a consequence the trans-acting factors and cis-acting chromatin modification states regulating a given gene are extremely rare. Transcription is affected by events taking place many thousands of base pairs away from the start, a property enabl ...
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1
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TERMINÉ
ODICIS - One DIsplay for a Cockpit Interactive Solution (ODICIS)
Date du début: 1 mai 2009, Date de fin: 30 avr. 2012,
"ODICIS project aims at developing a single display cockpit and at studying its concept of use. This addresses three current major aeronautics needs: system architecture flexibility, useful surface optimization and information continuity. Therefore the project will improve the operational safety and efficiency and reduce the aircraft development cost. The first objective is to prove the technical ...
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9
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TERMINÉ
Bis(alkyl-imidazolyl)propionate (BAIP) based bio-inspired mono-nuclear non-heme iron(II) complexes that catalyze challenging oxidative transformations of organic compounds (BAIPFeOTC)
Date du début: 1 sept. 2015, Date de fin: 31 août 2017,
...xidation potentials for O2 activation,(iii) To study the reactivity towards oxidants (H2O2, O2) and the catalytic properties in challenging oxidation transformations (alkane hydroxylation, alkene cis-dihydroxylation) of the corresponding iron complexes. (iv) To carry out detailed mechanistic investigations on isolated and/or spectroscopically well-characterized iron complexes and intermediates tha ...
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