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Plus de 40 projets européens trouvés

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 TERMINÉ 

Combatting Bacterial Resistance in Europe - Molecules against Gram Negative Infections (COMBACTE-MAGNET)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2021,

Antimicrobial resistance (AMR) is a major global public health threat, and most troublesome is the rapid emergence and dissemination of multidrug resistant (MDR) Enterobacteriaceae, Acinetobacter species and Pseudomonas aeruginosa. There is an unmet medical need to prevent P. aeruginosa infection in critically ill patients and to develop new antibiotics for infections caused by Gram-negative bacte ...
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 44

 TERMINÉ 

Paediatric Clinical Research Infrastructure Network (PedCRIN)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Children’s health is a major societal challenge for Europe and the world, requiring development of paediatric medicines and treatments strategies based on evidence derived from clinical trials demonstrating efficacy and safety in infants and children, rather than on uncritical extrapolation from adult data (over 50 % of the medicines used for children had not been tested in this specific age group ...
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 16

 TERMINÉ 

Boost Brittle Bones Before Birth (BOOSTB4)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Osteogenesis imperfecta (OI) is, in its severe forms, a devastating inherited disorder characterised by brittle bones. A person with severe OI is affected throughout their lifetime with repeated, multiple fractures, considerable pain and handicap. There is no curative or effective treatment for OI. Our preclinical studies and initial clinical cases have demonstrated that transplantation of fetal m ...
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 13

 TERMINÉ 

INtestinal Tissue ENgineering Solution (INTENS)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Short Bowel Syndrome (SBS) is a condition that occurs when part or the entire small intestine is missing or has been removed during surgery. This condition renders the bowel incapable of fulfilling its nutritional function (intestinal failure). There is no cure for SBS. Parenteral (intravenous) nutrition (PN) and bowel transplantation are currently the preferred options for nutrition in children a ...
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 9

 TERMINÉ 

Big data against childhood Obesity (BigO)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,

Childhood and adolescent obesity is a major global and European public health problem. Currently, public actions are detached from local needs, mostly including indiscriminate blanket policies and single-element strategies, limiting their efficacy and effectiveness. The need for community-targeted actions has long been obvious, but the lack of monitoring and evaluation framework and the methodolog ...
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 14

 TERMINÉ 

Harnessing Targeted Nanotheranostics to Reprogram Activated Leukocytes in Inflammatory Bowel Disease (LeukoTheranostics)

Date du début: 1 nov. 2015, Date de fin: 31 oct. 2020,

"Inflammatory bowel diseases (IBD) is a group of chronic inflammatory conditions of the gastrointestinal tract, including Crohn’s disease (CD) and Ulcerative Colitis (UC) that can impact both the large and small bowel. IBD affects approximately 3.7 million Europeans and its peak onset is in persons of 15 to 30 years of age. IBD imposes a significant burden on Europe with over €3B in annual health ...
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 2

 TERMINÉ 

DevelopIng Genetic medicines for Severe Combined Immunodeficiency (SCID) (SCIDNET)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Severe combined immunodeficiency (SCID) is a devastating rare disorder of immune system development. Affected infants are born without functional immune systems and die within the first year of life unless effective treatment is given. Treatment options are limited to allogeneic haematopoietic stem cell transplantation and autologous stem cell gene therapy. Over the last 15 years, gene therapy for ...
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 13

 TERMINÉ 

Treatment of late onset bacterial sepsis caused by vancomycin susceptible bacteria in neonates and infants aged under three months (NEOVANC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Vancomycin is the critically important antibiotic to treat neonatal Late Onset Sepsis (LOS) due to Gram positive bacteria in neonates, including Coagulase Negative Staphylococci (CoNS) and Staphylococcus aureus. These organisms also create biofilms which are extremely resistant to antibiotics. The increased incidence of LOS due to bacteria such as CoNS and MRSA in NICUs has led to a marked increas ...
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 14

 TERMINÉ 

Models of Child Health Appraised (MOCHA)

Date du début: 1 juin 2015, Date de fin: 30 nov. 2018,

Children’s health affects the future of Europe – children are citizens, future workers, parents and carers. Children are dependent on society to provide effective health services (UN Convention on the Rights of the Child). Models of child primary health care vary widely across Europe based on two broad alternatives (primary care paediatricians or generic family doctors), and a variety of models of ...
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 20

 TERMINÉ 

Phthalates and bisphenol A biomonitoring in Italian mother-child pairs: link between exposure and juvenile diseases (LIFE PERSUADED)

Date du début: 1 sept. 2014, Date de fin: 31 oct. 2018,

Background Bisphenol A (BPA) and di-2-ethylhexyl phthalate (DEHP) are two environmental endocrine disruptors (EDs) which – despite being non-persistent chemicals - are regularly detected in the environment, in food and, as a consequence, in humans. This is due to their continuous release from manufacturing or processing facilities, despite restrictions ...
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 3

 TERMINÉ 

Long-term, prospective study evaluating clinical and molecular biomarkers of epileptogenesis in a genetic model of epilepsy – tuberous sclerosis complex (EPISTOP)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Despite a great progress in the management of epilepsy, still one third of patients is refractory to available medications. The incidence of epilepsy is highest in infancy and 50% of children experience epilepsy-related comorbidities, such as developmental delay and autism. The development of epilepsy (epileptogenesis), extensively studied in animals, is barely studied in humans, as patients usual ...
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 16

 TERMINÉ 

Labeling of Enalapril from Neonates up to Adolescents (LENA)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Children are often treated as small adults—not as the special patients they are. Regulations exist to encourage the development of drugs and formulation for children. However, off-patent drugs are often administered to children without appropriate formulations or systematic investigations. Therefore, the paediatric use marketing authorisation (PUMA) has been designed.The EMA Paediatric Working Par ...
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 14

 TERMINÉ 

On the job learning by using ICF-CY in Social Pediatrics

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

Background/Context 2 major interconnected initiatives in the field of persons with disabilites (PwD) - the UN-Convention on the Rights of PwD (1986) and the International Classification of Functionning, Disabilty and Health (2002) (CY= children/youth version) focus on the full participation of PwD, on the necessity of inclusive settings and on a common language for professionals in order to descri ...
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 11

 TERMINÉ 

European Medical Information Framework (EMIF)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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 64

 TERMINÉ 

Youth Dreams Become True

Date du début: 1 juil. 2016, Date de fin: 30 nov. 2017,

Title of the project: Youth Dreams Become TrueWe would like to give opportunity for young adults within the framework of European Voluntary Service, what is not trough work, training and not attending a school but try out themselves by spreading their wings to be brave, to dream and to achieve their life plans or get closer to them. First of all the volunteers will be a part of a long-term ...
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 20

 TERMINÉ 

New approach to treatment of the blinding disease Retinopathy of Prematurity (ROP) (PREVENTROP)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,

"The overall objective is to develop a novel preventative intervention for the blinding disease retinopathy of prematurity (ROP) and other complications of prematurity. The PREVENTROP consortium proposes to conduct preclinical studies (pharmacological, pharmacodynamics, pharmacokinetics and toxicological) in models and/or clinical studies (including phase III clinical trial) of an EU designated o ...
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 10

 TERMINÉ 

Hemşire Adaylarının Avrupa Birliği'nde Halk Sağlığı Uygulaması ve Mesleki Eğitmi

Date du début: 19 sept. 2016, Date de fin: 18 sept. 2017,

Many economic and social factors, such as change of the societies' lifestyles, family structures, women's participation to the work life more effectively, migrations from rural areas to cities, inequalities at income distribution, involves new health problems and needs apart from the defined ones. Capability of serving to new needs for health at social field comes with the change in health service ...
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 4

 TERMINÉ 

Global Research in Paediatrics (GRiP)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2017,

Paediatric drugs (PD) lack appropriate testing. Most drugs have inadequate information about dosing regimen, dose adjustment and how to administer them. These are longstanding problems that unquestionably require concerted efforts at the international level. Both the US and the EU have introduced paediatric legislation that facilitates participation of children in research and pharmaceutical innov ...
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 24

 TERMINÉ 

Improving the practical skills of health professionals for the improvement of health of Children with intellectual disabilities - with focus on PraderVili Syndrome

Date du début: 1 juin 2015, Date de fin: 31 mai 2017,

Obesity is a rapidly growing problem worldwide leading to series of devastating complications of the health of the individual. Easy access to cheap calorie foods and passive lifestyle are the two most important factors for the growth of diseases caused by obesity. In individuals with Prader-Willi and other conditions where there is association between mental disability and excessive obesity, the p ...
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 2

 TERMINÉ 

Integrated Approaches to Food Allergen and Allergy Risk Management (IFAAM)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

Up to 20 million European citizens suffer from food allergy. However management of both food allergy (by patients and health practitioners) and allergens (by industry) is thwarted by lack of evidence to either prevent food allergy developing or protect adequately those who are already allergic. iFAAM will develop evidence-based approaches and tools for MANAGEMENT of ALLERGENS in FOOD and integrate ...
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 46

 TERMINÉ 

PanCare Childhood and Adolescent Cancer Survivor Care and Follow-up Studies (PanCareSurFup)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2017,

Over the last 40 years, treatment for childhood and adolescent cancer has improved greatly; 5- year survival after childhood cancer is now 80% in developed countries. Approximately 1 individual in 750 of young adults is now a childhood cancer survivor. Epidemiologic data on the number of European childhood cancer long-term survivors are not available, but estimates suggest a number between 300,000 ...
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 18

 TERMINÉ 

European clinical study for the application of regenerative heart valves (ESPOIR)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

Acquired and congenital heart disease can necessitate heart valve replacement. However, current heart valve substitutes are not considered ideal as they need anticoagulation, bearing the risk of bleeding when manufactured from non-organic material, or they degenerate when they derive from animals or human tissue donators (homografts) thereby leading to frequent reoperation especially in the young ...
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 15

 TERMINÉ 

Egual

Date du début: 1 juil. 2015, Date de fin: 30 nov. 2016,

There will be 18 volunteers serving at the project with different locations: volunteers will serve with refugees, roma communities, people with disabilities, children and young people and also in a community centre for prevention. One important goal of the project is to have growing commitment towards inclusive growth. This experience enables volunteers to discover new cultures and helps to foster ...
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 19

 TERMINÉ 

THALAssaemia MOdular Stratification System for personalized therapy of beta-thalassemia (THALAMOSS)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,

...Philipsen (Erasmus Universitair Medisch Centrum Rotterdam, The Netherlands), E.Katsantoni (Biomedical Research Foundation, Academy of Athens, Greece), S.Rivella (Cornell University, NY, USA - The Children's Hospital of Philadelphia, Philadelphia, USA), P.Holub (Masaryk University, Czech Republic), P. Moi (Cagliari University, Italy), S. Menzel and SL.Thein (King’s College Hospital, UK), E.Voska ...
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 14

 TERMINÉ 

A phase I/IIa clinical trial in Duchenne muscular dystrophy using systemically delivered morpholino antisense oligomer to skip exon 53 (SKIP-NMD)

Date du début: 1 nov. 2012, Date de fin: 30 avr. 2016,

Duchenne muscular dystrophy (DMD) is a progressive, lethal muscle degenerative condition arising from the absence of dystrophin in skeletal and cardiac muscles. 65% of DMD boys have out-of-frame deletions. Modulation of pre-mRNA splicing by exon skipping is the most promising molecular intervention in DMD. 2 Phase Ib and 2 Phase IIa clinical trials (MDEX Consortium in collaboration with Sarepta Th ...
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 10

 TERMINÉ 

Everyone Has Talent

Date du début: 1 juil. 2014, Date de fin: 30 nov. 2015,

Project partners: 9 hosting organisation in Hungary, 6 sending organisation, 1 coordinating organisation. Total: 16 cooperating organisations. Number of volunteers: 15 volunteers from Germany, France, Italy, Romania, Slovakia. The voluntary activity took place in Budapest, Debrecen, Kiskunhalas and Magyarmecske. Goals and themes of the activity: The project was offering long-term voluntary service ...
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 20

 TERMINÉ 

Step up to serve

Date du début: 1 janv. 2015, Date de fin: 31 oct. 2015,

We have involved 3 volunteers in the project, 2 volunteers from the Ukraine and 1 volunteer from the Netherlands. The sending organisation couldn?t send a volunteer for the 4th place. During the everyday task they will learn the following aspects as well: - To increase awareness among young people from a minority background on European citizenship. - To empower youth to take an active role in loc ...
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 7

 TERMINÉ 

Treat Iron-Related Childhood-Onset Neurodegeneration (TIRCON)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

Neurodegeneration with brain iron accumulation (NBIA) is a heterogeneous group of rare hereditary neurodegenerative disorders characterized by high levels of brain iron. The most common form is pantothenate kinase-associated neurodegeneration (PKAN). Classic PKAN and most other NBIA cases are characterised by early childhood onset and rapid progression. Currently, there is no proven therapy to hal ...
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 14

 TERMINÉ 

European multicenter network to evaluate pharmacokinetics, safety and efficacy of Meropenem in neonatal sepsis and meningitis (NEOMERO)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,

Previous studies have demonstrated the high frequency of bacterial sepsis in neonates and infants admitted to neonatal intensive care unit (NICU), often associated with serious complications or death. Many pathogens capable of causing nosocomial bacterial sepsis in neonates and young infants have developed resistance to the antibiotics considered of choice for treatment. Meropenem is an antibiotic ...
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 12

 TERMINÉ 

Suicidality: Treatment Occurring in Paediatrics (STOP)

Date du début: 1 nov. 2010, Date de fin: 30 avr. 2015,

The emergence of suicidality in patients receiving drug treatment is of concern because of the overall burden and the possible link with completed suicide. The lack of uniform requirements for defining, detecting and recording suicidality and the presence of disease related confounders create major problems. It is possible that Medication-Related Suicidality (MRS) differs from Psychopathology-Rela ...
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 19

 TERMINÉ 

Atopic diseases in changing climate, land use and air quality (ATOPICA)

Date du début: 1 oct. 2011, Date de fin: 31 mars 2015,

There is an urgent need to understand how global and regional climate, land use and air quality changes will impact human health. Our consortium constitutes an innovative and multidisciplinary approach to explore the combined pan-European impact of changes in climate, land use and air pollution on allergen pollen-induced diseases through a chain of quantitative physical and statistical models. We ...
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 11

 TERMINÉ 

Treatment of NEonatal seizures with Medication Off-patent: evaluation of efficacy and safety of bumetanide (NEMO)

Date du début: 1 oct. 2009, Date de fin: 31 mars 2015,

Neonatal hypoxic ischaemic encephalopathy (HIE) occurs in 2-3/1000 live births and is a major cause of both acute mortality and long-term neurodisability. Seizures are the hallmark of HIE. The clinical and electrographic seizure burden in babies with HIE can be considerable and is often not reduced by current antiepileptic drugs. Phenobarbitone remains the first line drug for neonatal seizures des ...
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 15

 TERMINÉ 

gramme for the prevention of postural disorders and scoliosis in children from small towns and rural areas (ILPR.02.02.00-96-032/10-00)

Date du début: 12 sept. 2012, Date de fin: 11 sept. 2014,

The overall objective of the project is reduction in the growth rates of acquiring of disability and improvement of the level and quality of life among children residing in towns and rural areas. Achievements: 1. One fully operating mobile orthopaedic diagnostic laborat ...
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 2

 TERMINÉ 

Transfer of know-how to ensure better care for Cystic Fibrosis patients in Zakarpatska region (HUSKROUA/1001/138)

Date du début: 27 mai 2012, Date de fin: 26 mai 2014,

Overall Objectives: Improving the quality of life of patients with Cystic Fibrosis and their families in the Zakarpatska region of Ukraine. Specific Objectives: 1. Improvement of the system of diagnosis, treatment and rehabilitation of patients with Cystic Fibrosis in the Zakarpatska region of Ukraine through transformation of know-how and experiences of Slovak and foreign experts.2. Improvement o ...
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 2

 TERMINÉ 

Development of Children’s Rehabilitation (HUSKROUA/1001/070)

Date du début: 31 oct. 2012, Date de fin: 29 avr. 2014,

Main project activity of the project is decreasing of the level of children’s disability on cross-border territory of Hungary and Ukraine, increasing the level of children’s rehabilitation at Rehabilitation Centres, decreasing the level of chronic diseases resulting in disability among children. Additionally project is about to procurerehabilitation equipment of Rehabilitation Centres’ areas, purc ...
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 2

 TERMINÉ 

Gene- Environment Interactions in Heart Development (CHeartED)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2012,

Cardiovascular malformation (CVM) is the commonest cause of childhood death in developed countries. In the EU there are 51,000 new cases each year and two million affected individuals. Yet, despite intensive research, the cause of 80% of CVM remains elusive. The mission of CHeartED is to identify genetic and environmental pathways that can be modified with the goal of reducing preventable CVM inci ...
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 11

 TERMINÉ 

European cradle (HUSKROUA/0901/005)

Date du début: 14 juil. 2010, Date de fin: 13 juil. 2012,

Overall objective:Decreasing the level of infant (up to 1 year) mortality and infant disablement on cross-border territory of Hungary and Ukraine.Specific objectives:1. To increase the percentage of infants’ recovery at children’s hospitals; 2. To decrease the level of postnatal infectious diseases of infants; and3. To decrease percentage of infants’ birth traumas and anoxaemia of cerebrum. Main ...
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 2

 TERMINÉ 

European Network for the Study of Orphan Nephropathies (EUNEFRON)

Date du début: 1 mai 2008, Date de fin: 30 avr. 2012,

"In this proposal, we have mobilized a critical mass of expertise to investigate, on a Europe-wide scale, the natural history and pathophysiology of rare inherited diseases affecting important structures of the kidney. The project will use and develop multiple models (in vitro and in vivo) with the aim to develop preventive, diagnostic and therapeutic interventions that should alleviate the burden ...
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 10

 TERMINÉ 

Holistic energy conscious and sustainable strategies in the health care building sector (BUILD HEALTH)

Date du début: 15 déc. 2007, Date de fin: 14 déc. 2011,

The European health care sector is facing future dramatic changes from e.g. the public demand for increased quality of health. Also Europe is facing substantial changes in the energy sector and has set out ambitious targets for abatement of GHG emissions and increased use of renewables. For the health care sector this could result in massive changes in the economy of the sector, which is among the ...
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 6

 TERMINÉ 

Setting up of an interactive e-Learning programme in Medical Parasitology and Mycology dedicated to the professionals who work in non specialized clinical laboratories: e-MEDICINimage

The e-MEDICINimage project enabled the creation of a remote continuing education scheme in the health sector (medical biology) related to parasitology and medical mycology. These two training schemes are built exclusively on e-Learning techniques and each of them offers a unique curriculum available in 5 languages (English, Spanish, French, Polish and Portuguese). This scheme, associated with the ...
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 16