3 projets européens trouvés
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TERMINÉ
Cellular and viral components in Respiratory Syncytial Virus (RSV) assembly and budding (RSV budding)
Date du début: 1 sept. 2012, Date de fin: 31 août 2014,
...ruses; however, the way by which viruses complete the process and free themselves from the plasma membrane presents a biophysical problem. A great number of viruses were shown to recruit the host’s cellular ESCRT fission pathway. Nevertheless, it has been demonstrated that RSV budding is independent of the ESCRT pathway and therefore studies of RSV have the potential to reveal a new paradigm for m ...
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2
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TERMINÉ
Molecular Adhesion and Interactions in the Nervous system (MAIN)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,
...urface-attached proteins establish cell-to-cell contacts and generate signals to control development and function of tissues. It is not clear how protein structure and interactions organize into intercellular assemblies to regulate signalling and adhesion. Using a hybrid approach and focusing on two cell-signalling systems critical for nervous system function, I will determine how protein conforma ...
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1
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TERMINÉ
Adoptive engineered T cell Trials to Achieve Cancer Killing (ATTACK)
Date du début: 1 déc. 2012, Date de fin: 30 nov. 2017,
The aim of this research is to exploit technology for nucleic acid delivery through the clinical testing of adoptive engineered T cells to treat cancer. Recent innovative developments in cancer gene-immunotherapy have led to very encouraging early clinical results. However, the use of engineered T cells is a challenging and complex field with further development and more proof-of-principle trials ...
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