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Ancient Pathogen Genomics of Re-Emerging Infectious Disease (APGREID)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

Here we propose a first step toward a direct reconstruction of the evolutionary history of human infectious disease agents by obtaining genome wide data of historic pathogens. Through an extensive screening of skeletal collections from well-characterized catastrophe, or emergency, mass burials we plan to detect and sequence pathogen DNA from various historic pandemics spanning at least 2,500 years ...
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The evolutionary success of humans can be attributed to our ability to adapt to ever-changing environments. This reproductive and adaptive success is demonstrated by the 7 billion living humans, occupying nearly every corner of the globe. However, the expansion of humans is an evolutionarily recent development; fossil, genetic and archaeological evidence indicates that humans and our hominin ances ...
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