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TERMINÉ
An integrated mulTidisciplinary appRoach towards a new generAtIon of aNtibiotics: Targeting function and cross-talk of bacterial Envelope proTein machineries (Train2Target)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Train2Target is a multidisciplinary European Training Network built to address the challenge of the discovery of alternative antimicrobials. Innovative strategies to deliver a next generation of drugs are urgently needed. The alarming threats and spread of multi-drug resistant bacteria is currently leaving clinicians with very limited options to combat infections especially those from Gram-negativ ...
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TERMINÉ
MOLECULAR BASIS OF ANTIBIOTIC TRANSLOCATION (Translocation)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
Multidrug resistant bacteria are now ubiquitous in both hospitals and the larger community. Drug-resistant pathogens are becoming increasingly pervasive, for example, the resurrection of tuberculosis provides one ominous example highlighting the risk associated with evolved drug resistance. Moreover, many pharmaceutical companies abandoned this field and no truly novel active antibacterial compoun ...
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