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 TERMINÉ 
The project's main aim is to develop a methodology to measure heavy metal contamination in capsicum - paprika - the region's main cash crop.Specific objectives:1. Developing a biosensing method for detection of heavy metal toxicity2. Selection of heavy metal resistant capsicum varietiesThe main activities of the project are: the detailed work plan shared by the partners (sample preparation for gre ...
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 2

 TERMINÉ 

Biosensor nanoarrays for environmental monitoring (BIOMONAR)

Date du début: 1 avr. 2010, Date de fin: 31 mars 2014,

BIOMONAR develops multiplexed nanoarray biosensors for environmental targets, i.e. pollutants and pathogens. The innovative approach engineers three sensor platforms (surface, liposomal, living cell) which exploit a panel of periplasmic binding proteins (PBPs) as the common selective element. The nanoarrays are integrated into a microfluidics system for in-situ monitoring. The strategy allows for ...
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 11

 TERMINÉ 

Enzymatic SO2 biosensor for rapid food safety monitoring (SO2SAFE)

Date du début: 1 oct. 2014, Date de fin: 28 févr. 2015,

Overall objective of the SO2SAFE Project is to develop a new miniaturized ready to use biosensor based on disposable screen printed electrodes (SPE) which will allow a highly sensitive, selective, fast, low-cost and user friendly method for determination of sulphites in crustaceans, since this is a type of food where the sulphite is commonly used. The novel solution will have a direct impact not o ...
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 1

 TERMINÉ 

Rapid Biosensor for the Detection of Mycotoxin in Wheat (MycoHunt)

Date du début: 1 sept. 2010, Date de fin: 31 août 2013,

...ps are invaded by certain species of Fusarium such as F. graminearum and F. culmorum. Our goal would be twofold: -developing a new sampling technique guaranteeing a 95% bulk transparency, -adapting a biosensor technology for the detection of deoxynivalenol. The electrochemical detection was selected as the amperometric sensor technology using a special biorecognitive layer proved to be the most re ...
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 19

 TERMINÉ 
RADAR is a 7-member consortium that aims to develop a robust, sensitive, and versatile label-free, biosensor platform for spot measurements and on-line monitoring of toxins and pollutants in food production processes and in the aquatic environment.Specificity towards chemical pollutants and toxins is achieved by using recombinant receptors (namely the estrogen receptor and the aryl hydrocarbon rec ...
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 7

 TERMINÉ 

Laser Multiplexed Biosensor (GLAM)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

... urine and to genitourinary cancers, to help oncologist to take better treatment decisions, approaching personalized medicine.GLAM will develop an integrated device based on novel label-free photonic biosensors with ultra-sensitivity, simplicity of use, portability, multiplexing and low cost. GLAM capitalizes on the unprecedented sensitivity achieved using laser microring resonators to detect key ...
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 10

 TERMINÉ 
...nd electrospun nanofibres are both hot topics individually in the biomedical sciences, with applications including tissue engineering, regenerative medicine, drug release, affinity chromatography and biosensors. This proposal combines these two leading-edge approaches to generate entirely novel materials with broad utility in biomedical engineering. Molecular imprinting is a form of template assis ...
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 1

 TERMINÉ 

"Early detection of HIV-1 using ultra-sensitive, rapid capacitive biosensor" (CAPHIV)

Date du début: 1 sept. 2011, Date de fin: 30 sept. 2013,

"The HIV pandemic continues to be a worldwide public-health problem. The virus, which is spread through sexual contact, exposure to infected blood, or through shared syringes, is highly infective, rapidly mutates, and has no cure. Because there is no effective vaccine or other prophylaxis available, the current best practice and standard of care for those infected is an early, accurate diagnosis ...
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 7

 TERMINÉ 
"The objective of the FOODSCAN project is to develop a novel and automated biosensor platform for pesticide and other chemical residue detection incorporating membrane-engineered cells with pesticide-specific antibodies. The system is primarily based on the Bioelectric Recognition Assay (BERA) technology. Furthermore a specially designed electronic interface is realized in order to acquire and man ...
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 10

 TERMINÉ 
...on of becoming the leading provider of analyte evaluation systems, with a turnover of €30.5m by 2020. To realise this vison we will add a new product line to our portfolio by exploiting an existing biosensor technology that we have developed, as well as the experience and contacts gained on a parallel project, which is currently yielding high growth. We have identified within our target market the ...
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 1

 TERMINÉ 
"Cellular bioenergetics play a key role in the pathogenesis of acute and chronic neurological disorders. Novel sensors and analytical systems in combination with biomedical imaging can provide powerful new insights into the role of cellular bioenergetics in the propagation of disease states. OXY-SENSE is an Industry-Academia partnership of experienced neuroscientists, experts in optical oxygen sen ...
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 4

 TERMINÉ 
...burning problems in the agro-food sector.The proposed feasibility study represents the first step to the development and commercialisation of a portable, mobile wireless device, cantilever-based nano-biosensor, to measure in field the B1, M1-aflatoxins to very low level values in animal feedstock and in the milk-chain.The aim is to give a dramatic innovative solution for solving all the problems c ...
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 1

 TERMINÉ 
...e and cheap instrument for the wine industry, able to provide a quantitative and reliable evaluation of the presence of grey rot infection in grapes in a very short time. The instrument is based on a biosensor system and on an innovative analysis method, that allows a precise and very fast analysis procedure, i.e. in less than one minute, which is compatible with the quality control procedures app ...
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 10

 TERMINÉ 

Electrochemiluminescent biosensor for screening of coeliac disease (ECLOBIOSENS)

Date du début: 1 juin 2010, Date de fin: 31 mai 2012,

...bjective of ECLOBIOSENS is to develop a generic technological platform for point-of-care diagnostics capable of simultaneous genomic and proteomic electrochemiluminescent detection. As a model system biosensor arrays for the screening of coeliac disease will be developed based on the simultaneous detection of nucleic acids (HLA typing) and protein molecular markers (auto-antibodies) associated wit ...
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 1

 TERMINÉ 
Biosensors possess recognition elements that bind to target molecules which lead to detectable signals; they are made of two basic components: (i) a bioreceptor or biorecognition element; and (ii) a transducer element. The bioreceptor system interacts with the target analyte and this interaction is monitored by the transducer, which converts the information into a measurable effect such as an elec ...
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 6

 TERMINÉ 

ENZYMATIC SO2 BIOSENSOR FOR RAPID FOOD SAFETY MONITORING (SO2SAFE)

Date du début: 1 juil. 2015, Date de fin: 30 juin 2017,

...mum concentration levels in foodstuff are regulated, and must be ensured by the agro-food processing industries. BIOLAN has developed at the laboratory scale a simple, reliable and specific enzymatic biosensor for sulphite determination and has obtained relevant data that support the innovative project here proposed.Main objective of SO2SAFE project is to develop a novel miniaturized ready to use ...
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 1

 TERMINÉ 
...thly, assays typically used for gluten detection exploit indirect sandwich assays, typically requiring 6-8 hours to complete. Here we propose to address each of the challenges to develop reagentless biosensors for in-situ detection of gluten in foodstuffs by using aptamers. Aptamers are getting more and more attention in biosensor area especially because of their superior properties over antibod ...
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 1

 TERMINÉ 

Large Scale Protein Library Screening Biosensor (NanoPP)

Date du début: 1 janv. 2016, Date de fin: 30 juin 2017,

In this application a platform is proposed that builds on preliminary work from ERC starting grant NanoP in order to develop a technology for high throughput electronic recognition of a large library of proteins using nanometer sized channels. These channel (or nanopore) dimensions are on the same order of magnitude as the proteins that we are using, making a natural confinement mechanism. Importa ...
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 2

 TERMINÉ 
...ysis in Europe. Currently, a pesticide analysis costs an average of €300 per sample since it requires specific staff and high technology equipments. We have developed a prototype of BEEP-WATER biosensor technology able to detect and quantify on site a wide range of chemical contaminants including pesticides, heavy metals and emerging contaminants in water saving the cost associated to current lab ...
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 1

 TERMINÉ 
Pathfinder is an important research project focused on development of innovative means of detecting important pathogenic organisms associated with food poisoning. This will be achieved using biosensor technology capable of detecting many different pathogens simultaneously. To achieve the main goal the Marie Curie Fellow, Dr. Nitsara Karoonuthaisiri from Thailand will bring her skills in microarra ...
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 1

 TERMINÉ 
...y time they need to. Potential fields of use are marine environment pollution monitoring, marine research and quality control in seawater aquaculture, a sector in Europe highly occupied by SMEs. The biosensors developed in the project go far beyond the current state-of-the art in terms of accuracy, reliability and simplicity in operation by combining innovations in nanotechnology and molecular s ...
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 19

 TERMINÉ 
Early warning systems that can provide extreme sensitivity with exquisite selectivity are required to assess chemical contamination of estuarine and coastal areas. SEA-on-a-CHIP aims to develop a miniaturized, autonomous, remote and flexible immuno-sensor platform based on a fully integrated array of micro/nano-electrodes and a microfluidic system in a lab-on-a-chip configuration combined with ele ...
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 19

 TERMINÉ 
... actual prevalence of transgenic material in food and feed, which is unknown.The GMOsensor proposal intends to establish an innovative and well-organised scientific network aiming at advancing on nanobiosensor devices to assess the presence of GMO in food and feed products. The achievement of high throughput sensitive analysis requires novel approaches that combine different research areas. State- ...
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 6

 TERMINÉ 

PHOTONIC BIOSENSOR FOR SPACE APPLICATION (PBSA)

Date du début: 1 déc. 2012, Date de fin: 30 avr. 2015,

"PBSA project is focused on the implementation of a Lab-on-a-chip (LoC) for space Life exploratory missions. Advanced terrestrial technologies in the field of biosensors are combined for the development of a novel solution ready to be tested for the space environment. This approach employs recent advances in the space developed biochemistry related to immunoassays with two main novel technologies, ...
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 4

 TERMINÉ 
Pathfinder is a important research project focused on development of innovative means of detecting important pathogenic organisms associated with food poisoning. This will be achieved using biosensor technology capable of detecting many different pathogens simultaneously. To achieve the main goal the Marie Curie Fellow, Dr. Nitsara Karoonuthaisiri from Thailand will bring her skills in microarray ...
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 1

 TERMINÉ 

CALPASTATIN BIOSENSOR FOR MEAT TENDERNESS PREDICTION (TENDERCHECK)

Date du début: 1 oct. 2007, Date de fin: 31 mars 2010,

...m proteolysisis and is made up of three main proteins calpain I, calpain II and calpastatin. The main objective of this project is to design and develop an analytical instrument based on a capacitive biosensor for the rapid detection of the two proteins calpain I and calpastatin The tendercheck device will allow a rapid tenderness grading with a correlation of around 80...
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 10

 TERMINÉ 
...ambitious goals, VIBRANT-BIO will exploit plasmonics and newly discovered two-dimensional nanomaterials such as graphene and explore the ultimate limits of light-matter interaction to demonstrate biosensors with extreme sensitivity, throughput and functionality, well beyond the state-of the art. It will innovatively integrate nanoplasmonics with advanced photonics and bioanalytical tools to dramat ...
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 1

 TERMINÉ 
...on, which requires creation of new probes. We propose to design genetically encoded Cl-sensitive sensors capable to monitor activation of Cl-selective GABAA receptors. We will develop the probe “BioSensor-GABAR”: a chimeric GABAA receptor subunit with Cl-Sensor inserted to cytoplasmic domain. Development of “GABAR-Sensors” would allow us (i) to monitor activation of the GABAA receptors (ii) to es ...
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 1

 TERMINÉ 
NANOIMMUNOTECH (NIT) is a nanobiotechnology Company which is the sole exploiter of an exclusive ultrasensitive biosensor nanotechnology, called HEATSENS. Thanks to the innovation of using gold nanoprisms, it is able to detect analytes with a low level of detection (attomolar detection limit, one million times more sensitive than competitors), in a faster, cheaper and simpler way than current metho ...
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 1

 TERMINÉ 
...in my PhD research. In this research, I visualized extracellular signal regulated kinase (ERK) activity in the skin of living mice by FRET-based observation of transgenic mouse expressing a sensitive biosensor for ERK. By this approach, I found a novel pattern of intercellular ERK activity propagation, which we named SPREAD. In SPREAD, bursts of localized ERK activation concentrically propagated t ...
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 1

 TERMINÉ 
...ader, Dawid Nidzworski, PhD, a young Polish scientist has proven, within the framework of a grant from the Foundation for Polish Science – VENTURES FNP, that it is possible to develop an innovative biosensor to detect all serotypes of the influenza virus.For his discovery, he received: The Award of the Minister of Science and Higher Education for international achievements in inventions in 2013 an ...
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 1

 TERMINÉ 

Micro-ring resonator-based biophotonic system for food analysis (BIOFOS)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,

...ning tools that will be still reliable but simple, fast, low-cost, sensitive and portable for in-situ application is thus urgent. BIOFOS aims to address this need through a high-added value, reusable biosensor system based on optical interference and lab-on-a-chip (LoC) technology.To do this, BIOFOS will combine the most promising concepts from the photonic, biological, nanochemical and fluidic pa ...
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 12

 TERMINÉ 
...target population of HEARTEN are patients with chronic and acute HF, either post-ischemic or with dilated cardiomyopathy, requiring occasionally re-admittance into hospitals. The idea is to develop biosensors that detect and quantify novel breath and saliva HF biomarkers, being identified through analytical techniques. These biomarkers reflect the health status of the patient and identify whether ...
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 14

 TERMINÉ 

Giant Organic Magnetoresistance BioSensing (GOMBS)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2015,

The GOMBS project prepares the commercialization of ultrasensitive point-of-care biosensors for early-stage detection of life-threatening diseases, based on the largest MR effect ever observed at room temperature and small magnetic fields, recently discovered by the PI [Science 341, 257 (2013)]. Target biomolecules are specifically attached to the sensor and magnetic nanoparticle (NP) labels, and ...
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 1

 TERMINÉ 
"The main S&T objective of CATSENSE is to design novel high performance catalysts and biosensors by a new interactive approach combining i. the production of mono and bi-metallic gas-phase clusters of controlled homogeneity, ii. the extensive characterisation of their morphology, structure (ex and in situ) and optical properties, iii. theoretical modelling and screening, and iv. catalytic and bios ...
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 7

 TERMINÉ 

Sensing toxicants in Marine waters makes Sense using biosensors (SMS)

Date du début: 1 déc. 2013, Date de fin: 31 août 2017,

...hat will host in a single unit—the Main Box (MB)—a Sampling Module and an Analysis Module. The former will contain sample collection and treatment components, whereas the latter will include four biosensor sub-modules that will enable detection and measurement of algal toxins and their associated algal species; several hazardous compounds (tributyltin, diuron and pentaBDPE); sulphonamides and a se ...
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 10

 TERMINÉ 

"Biosensors, Reporters and Algal Autonomous Vessels for Ocean Operation" (BRAAVOO)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2016,

...to develop innovative solutions for real-time in-situ measurements of high impact and difficult to measure marine pollutants. The concept of BRAAVOO is based on a unique combination of three types of biosensors, which will enable both the detection of a number of specific marine priority pollutants as well as of general biological effects that can be used for early warning. First, innovative bimod ...
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 9

 TERMINÉ 

Simple Atto Molar Detection and Nanoscale Kinetics of Biomolecules (SAMDBC)

Date du début: 2 juil. 2014, Date de fin: 1 juil. 2016,

... biological electron transfer will be revisited and re-evaluated. In parallel to this, we plan to use the natural redox activity of selected amino acids within a protein to establish a simple type of biosensor, with approximately attomolar detection sensitivity for label free proteins. Recently, the ability to observe electrocatalytic activity of single NP’s (due to collision with an electrode) wa ...
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 1

 TERMINÉ 
...d state of the art materials characterisation methods. Firstly I aim to transform the way that we can currently detect disease through innovations in the design and development of nanomaterials-based biosensors that could be used to detect a number of diseases with global implications, such as cancer, malaria, heart failure and tuberculosis. These innovations in biosensor design will involve both ...
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 2

 TERMINÉ 
.... To tackle these problems, we will investigate the tolerance and resistance to B-Raf inhibitors with single cell resolution in vivo. We have established melanoma cell lines stably expressing EKAR-EV biosensor that reports ERK activity in living cells. In vitro, the melanoma cells show homogenous responses to BRaf inhibitors, whereas intravital analysis indicate that there is considerable heteroge ...
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 2