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 EN COURS 

Combinatorial Aspects of Computational Geometry (CombiCompGeom)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

The project focuses on the interface between computational and combinatorial geometry. Geometric problems emerge in a variety of computational fields that interact with the physical world.The performance of geometric algorithms is determined by the description complexity of their underlying combinatorial structures. Hence, most theoretical challenges faced by computational geometry are of a distin ...
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 1

 EN COURS 
Synthetic biology is an emerging discipline that offers powerful tools to control and manipulate fundamental processes in living matter. We propose to develop and apply such tools to modify the genetic code of cultured mammalian cells and bacteria with the aim to study the role of lysine acetylation in the regulation of metabolism and in cancer development. Thousands of lysine acetylation sites we ...
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 1

 EN COURS 

Directed Protein Evolution for Synthetic Biology and Biocatalysis (ES-Cat)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2021,

ES-Cat will use directed evolution as a tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes – that perform at levels near perfection. Instead of seeing rational and combinatorial approaches as alternatives, we combine them in this network to achieve a ‘smarter’ and more efficient exploration of protein sequence space. By harnessing the forces of Dar ...
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 11

 EN COURS 
Plasmids are known to be major contributors to lateral gene transfer in bacterial genomes; however, their comprehensive evolutionary role within bacterial communities is poorly understood. Recently we have developed cutting edge abilities to access a plasmid population (plasmidome) of a given microbial community, and applied them to rumen microbial communities. These abilities are an element long- ...
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 1

 EN COURS 

SOcial Cognitive Robotics in The European Society (SOCRATES)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,

SOCRATES is a PhD training program for 15 young researchers, created to develop the field of Social Robotics with an application focus on Robotics in Eldercare. The research in Social Robotics has a common theme of Interaction Quality, which is a concept for characterization of how a specific mode of interaction is fit for a given task, situation, and user. Interaction Quality often changes, for i ...
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 8

 TERMINÉ 
High-resolution fluorescence imaging, including super-resolution microscopy and high-speed live cell imaging, are used to obtain quantitative information on the structural organization and kinetics of cellular processes. The contribution of these high-resolution techniques to cell biology was recently demonstrated for dynamin- and ESCRT-driven membrane fission in cells. While they advance our know ...
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 1

 TERMINÉ 
Alcohol addiction ranks among the primary global causes of preventable death and disabilities in human population, but treatment options are very limited. Rational strategies for design and development of novel, evidence based therapies for alcohol addiction are still missing. Within this project, we will utilize a translational approach based on clinical studies and animal experiments to fill thi ...
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 13

 TERMINÉ 

TRANSITION FROM LINEAR 2 CIRCULAR: POLICY AND INNOVATION (R2PI)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2019,

"R2π examines the shift from the broad concept of a Circular Economy (CE) to one of a Circular Economy Business Models (CEBM), by tackling both market failure (business, consumers) and policy failure (conflicts, assumptions, unintended consequence). Its innovation lies in having a strong business-focus, examining stimuli beyond environmental goals (including ICT and eco-innovation), and in examini ...
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 14

 TERMINÉ 
"In ZERO-PLUS, a comprehensive, cost-effective system for Net Zero Energy (NZE) settlements will be developed and implemented. The system will be composed of innovative solutions for the building envelope, for building energy generation and management, and for energy management at the settlement level. A reduction of operational energy usage to an average of 0-20 kWh/m2 per year (compared with the ...
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 18

 TERMINÉ 

Eastern Mediterranean Regional Training Partnership

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

The main objective of the EastMed project is the development of a HEI-level Massive Open Online Course (MOOC), focusing on the region of the Eastern Mediterranean. The MOOC, entitled "EU and the Eastern Mediterranean: Prospects and Challenges", will give an emphasis to the concurrent refugee crisis and energy security, and will be developed and delivered in accordance with ECTS/ESG.Europe and the ...
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 4

 TERMINÉ 

Nexus of European Centers Abroad for Research on EHEA

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

The overall aim of the NEAR-EU project is to broaden the field of European integration studies by incorporating the domain of higher education in the research and activities of European Study Centers. The project will develop an inter-regional, collaborative academic space to enhance the study of European higher education policy and academic internationalization. The project intends to establish B ...
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 1

 TERMINÉ 
Terrestrial and marine ecosystems provide essential services to human societies. Anthropogenic pressures, however, cause serious threat to ecosystems, leading to habitat degradation, increased risk of collapse and loss of ecosystem services. Knowledge-based conservation, management and restoration policies are needed to improve ecosystem benefits in face of increasing pressures. ECOPOTENTIAL makes ...
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 47

 TERMINÉ 
A collective effort is needed to create the environmental research infrastructure for answering pressing questions in a world of rapid social, economic and environmental change.The overall aim of the eLTER project is to advance the European network of Long-Term Ecosystem Research sites and socio-ecological research platforms to provide highest quality services for multiple use of a distributed res ...
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 31

 TERMINÉ 
Chronic kidney disease (CKD) is an important public health problem worldwide, especially in older people. Indeed, population aging in industrialized countries is accompanied by an increase in the prevalence of CKD and its complications. Although its prevalence and the importance of an early diagnosis to prevent complications such as end-renal stage disease (ESRD), screening programme in Europe are ...
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 11

 TERMINÉ 

Perception and Action in Complex Environments (PACE)

Date du début: 1 avr. 2015, Date de fin: 31 mars 2019,

The PACE research and training programme sits at the interface between basic science, technology and clinics, in order to unveil how humans control and adapt their movements in complex, naturalistic environments. Such a research agenda has major consequences for understanding how these movements are impacted by specific brain insults and how these impairments can be compensated for via new rehabi ...
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 10

 TERMINÉ 

The interpretive function and syntactic category of noun classes (NOUN CLASSES)

Date du début: 1 mars 2014, Date de fin: 1 mars 2019,

A central goal of modern linguistic theory is to find out what properties are shared, and what properties are different across human languages. Following Chomsky (1981, 1988), the shared properties are attributable to Universal Grammar, i.e. our innate capacity to learn a human language, and following Borer (1984) the variable ones are due to cross-linguistic differences in inflectional elements ...
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 1

 TERMINÉ 

Sustainable production of next generation biofuels from waste streams (WASTE2FUELS)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,

WASTE2FUELS aims to develop next generation biofuel technologies capable of converting agrofood waste (AFW) streams into high quality biobutanol.Butanol is one of the most promising biofuels due to its superior fuel properties compared to current main biofuels, bioethanol and biodiesel. In addition to its ability to reduce carbon emissions, its higher energy content (almost 30% more than ethanol), ...
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 20

 TERMINÉ 
The dysregulation of signaling pathways that mediate cell proliferation, survival and migration is an underlying cause of many cancers. In particular, dysregulation and over-expression of avb3 integrin, membrane-type-1 matrix metalloproteinase (MT1-MMP; also known as matrix metalloproteinase-14, MMP14) and vascular endothelial growth factor receptor-2 (VEGFR2) correlate with poor prognosis in many ...
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 1

 TERMINÉ 

Targets and biomarkers for antiepileptogenesis (EPITARGET)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Epilepsy is a devastating condition affecting over 50 million people worldwide. This multidisciplinary project is focused on the process leading to epilepsy, epileptogenesis, in adults. Our main hypothesis is that there are combinations of various causes, acting in parallel and/or in succession, that lead to epileptogenesis and development of seizures. Our central premise and vision is that a comb ...
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 20

 TERMINÉ 

Teaching Excellence in Israel

Date du début: 15 oct. 2015, Date de fin: 14 oct. 2018,

Teaching excellence if of primary importance for the learning environment in higher education. Thus, TEACHEX is a project conceived to contribute to the continuous professional development of academic staff by offering adequate support structures (Centers for Teaching Excellence)and innovative, high-quality, flexible programs designed to promote better teaching and therefore enhanced learning as ...
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 14

 TERMINÉ 
"Traumatic brain injury (TBI) is among the leading causes of death and disability and the main cause of death among the under-45s. Most patients with moderate to severe TBI are admitted to intensive care units (ICUs)The “PROSAFE” ICU network was recently established in 6 European countries through EU funding (PHEA 2007331), and has continued to collect high-quality data beyond the grant duration. ...
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 11

 TERMINÉ 
The proposal establishes a Network - "Crisis, Conflict and Critical Diplomacy: EU Perceptions in Ukraine and Israel/Palestine" (C3EU) - focused on EU images in key issue areas of economy, politics, foreign policy, energy, climate change, RS&I, civil society and culture/education.The EU aims to engage more effectively with 3rd country publics and stakeholders. Ukraine and Israel/Palestine are curre ...
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 6

 TERMINÉ 
Topological superconductors are known to harbor Majorana bound states at their boundaries and inside vortex cores. Their non local properties and non-Abelian exchange statistics make Majorana bound states potential candidates in fault tolerant quantum computational schemes. Recently it has been pointed out that interacting topological superconductors support even more exotic non-Abelian excitation ...
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 1

 TERMINÉ 

Investigating Directed Information (DirectedInfo)

Date du début: 1 août 2013, Date de fin: 31 juil. 2018,

This research investigates a new measure that arises in information theorycalled directed information. Recent advances, including our preliminary results, shows thatdirected information arises in communication as the maximum rate that can be transmitted reliablyin channels with feedback. The directed information is multi-letter expression and therefore veryhard to optimize or compute.Our plan is f ...
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 1

 TERMINÉ 

PhD on Innovation Pathways for TES (INPATH-TES)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2018,

Following the EC SET-Plan Education and Training Roadmap, the concept of this proposal is to develop a joint PhD programme between universities and research centres, on the topic of Thermal Energy Storage (TES). The goal of INPATH-TES is to create a network of universities and research institutes to implement a joint PhD programme on TES technologies. The final result of such a network is to educa ...
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 22

 TERMINÉ 
"Exposure to PM2.5 has been associated with increased risk of myocardial infarction, reduced birth weights, cardiovascular and respiratory disease. Climate changes will lead to warmer air temperatures (Ta) and more extreme weather events,which are associated with increased morbidity and mortality in sensitive populations. Current epidemiological studies on the health effects of PM2.5 and Ta have m ...
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 1

 TERMINÉ 

Embodied and Abstract Concepts in Sensory-motor Deprivation (EACISD)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2018,

How is information organized in the brain? Does our understanding of everyday concepts rely on our perceptual experience, and our ability to sense them? And can this uncover how abstract information is coded in our brains?These puzzles are at core of cognitive neuroscience and brain organization. Two major theoretical bodies differ in their account of neural concept organization: Classical cogniti ...
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 1

 TERMINÉ 

New Directions in Meta-Kernelization (MetaKer)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

Preprocessing for the purpose of simplifying problem instances is a universal algorithmic technique applied in almost every software implementation. Understanding and assessing preprocessing techniques is therefore of crucial practical importance in computer science. Kernelization is a notion developed in the area of parameterized complexity that provides a the only known reasonable mathematical m ...
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 1

 TERMINÉ 
The human forebrain plays critical roles in cognition, motor function, and emotion. Impaired forebrain development and function are associated with neurodevelopmental disorders, including epilepsy.Early onset of epilepsy is a spectrum of disorders with strong genetic components that could be difficult to precisely diagnose and provide effective treatments. A major and underexplored cause of comple ...
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 1

 TERMINÉ 

School Food Environments (School Food Environ.)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

Obesity rates have nearly tripled since the 1980’s in the United States and in many European countries, and this rise has been particularly alarming with regards to children. To combat childhood obesity, policy makers have increasingly been examining school food environments. School food environments are defined as policies enacted by a school affecting students’ dietary intake during the school d ...
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 1

 TERMINÉ 
This proposal is aiming at understanding the structural basis of the type 1 ryanodine receptor (RyR1) regulation by post-translational modifications and by small molecules. RyR1 is present on the sarcoplasmic and endoplasmic reticuli of many mammalian cell types, most notably, in skeletal muscles. RyR channels are required for calcium release from intracellular stores, a process essential for exci ...
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 1

 TERMINÉ 

Sweet Pepper Harvesting Robot (SWEEPER)

Date du début: 1 févr. 2015, Date de fin: 31 janv. 2018,

In modern greenhouses there is a high demand to automate labour. The availability of a skilled workforce that accepts repetitive tasks in harsh greenhouse climate conditions is decreasing rapidly. The resulting increase in labour costs and reduced capacity puts major pressure on the competitiveness of the European greenhouse sector. Present robotization of this labour has entered an high level of ...
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 6

 TERMINÉ 
Advance_eLTER marks a crucial step in building the distributed European Research Infrastructure of Long-Term Ecosystem Research sites and socio-ecological research platforms (eLTER RI) to provide highest quality data and services complementary to the European and global environmental RIs. The project will conduct important conceptual work and preparatory steps towards enabling European-scale inves ...
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 28

 TERMINÉ 

Superfluidity: a super-fluid, cloud-native, converged edge system (SUPERFLUIDITY)

Date du début: 1 juil. 2015, Date de fin: 31 déc. 2017,

Superfluidity is “a state in which matter behaves like a fluid with zero viscosity”. Our project aims at achieving superfluidity in the network: the ability to instantiate services on-the-fly, run them anywhere in the network (core, aggregation, edge) and shift them transparently to different locations.The SUPERFLUIDITY project tackles crucial shortcomings in today’s networks: long provisioning ti ...
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 18

 TERMINÉ 

MIcro KErneL virtualizAtioN for hiGh pErfOrmance cLOud and hpc systems (MIKELANGELO)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2017,

MIKELANGELO is a project, targeted to disrupt the core underlying technologies of Cloud computing, enabling even bigger uptake of Cloud computing, HPC in the Cloud and Big Data technologies under one umbrella. The vision of MIKELANGELO is to improve responsiveness, agility and security of the virtual infrastructure through packaged applications, using lean guest operating system OSv and superfast ...
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 9

 TERMINÉ 
The overall aim of this joint exchange programme is to establish a long term bilateral network (Europe & Australia) of researchers active in functional genomics in crustacean aquaculture, strengthen research capacity through exchange of knowledge and expertise in this area, and develop integrated approaches to investigate the main metabolic processes to improve crustacean production due to its hig ...
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 2

 TERMINÉ 
"INNOSTORAGE proposal is driven by the need to develop efficient thermal storage (TES) systems using phase change materials (PCM). One of the main contributions to the rational use of energy is given by the TES systems. They accommodate efficient storage of thermal energy, promoting the possibility of using renewable energy such as solar energy, ambient cold and residual heat. The use of PCM for T ...
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 5

 TERMINÉ 

Sample In - Answer Out Optochemical Sensing Systems (SAMOSS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

Biosensor development is a very promising and prospective field of research in food- clinical- and environmental analysis. Besides conventional analytical methods biosensors specifically detect only some decisive components. However, miniaturised sensor systems are able to detect components in the femto/ato-gramm region with almost no interference to other components in the investigated system. Th ...
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 8

 TERMINÉ 
Inverse problems that are governed by partial differential equations arise in many applications in computational science and engineering. Solving these large scale problems is a real challenge to the existing numerical methods, as they are generally highly ill-posed and non-convex. These difficulties are usually handled by introducing statistical Bayesian estimation methods that promote a-priori k ...
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 2

 TERMINÉ 

Misfolded SOD1 Toxicity in Amyotrophic Lateral Sclerosis (Misfolded SOD1-ALS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

Amyotrophic lateral sclerosis (ALS) is a late-onset fatal neurodegenerative disease characterized by the loss of upper and lower motor neurons. The reason for the degeneration of motor neurons in ALS is still unknown. Mitochondria have been implicated as a possible target for toxicity by several studies reporting a range of dysfunctions and the toxic binding of misfolded SOD1 to mitochondrial targ ...
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 1