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 TERMINÉ 

Dynamics of Inequality Across the Life-Course: structures and processes (DIAL)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2021,

Existing and rising inequalities pose fundamental challenges to European societies and economies. Large disparities in human and social capacities are counterproductive to a sustainable and creative economy and participatory governance and inclusion. The increasing gulf between rich and poor, exacerbated by the recent financial and economic crises, is a key concern. The sources of inequalities in ...
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 18

 TERMINÉ 
The simulation of Partial Differential Equations (PDEs) is an indispensable tool for innovation in science and technology.Computer-based simulation of PDEs approximates unknowns defined on a geometrical entity such as the computational domain with all of its properties. Mainly due to historical reasons, geometric design and numerical methods for PDEs have been developed independently, resulting i ...
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 4

 TERMINÉ 
Analysing the link between reproduction and women’s social status, this project explores social responses to pregnancy, birth and childrearing from the late Neolithic to the late Iron Age (c.3000-15 BC) through case studies in central Europe. Motherhood and childrearing, often seen as natural, mundane and inevitable parts of women’s lives, are also cultural and historically contingent practices th ...
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 1

 TERMINÉ 
It is often taken for granted that the Greek-Arabic translation movement (8th-10th c.) that made the whole bulk of Classical Greek scientific and philosophical literature available in Arabic (and that was later handed over to Europe in Latin translations) owes much to the preceding period in the history of transmission of this scientific and philosophical literature, namely translations into the S ...
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 2

 TERMINÉ 
Phenotypic variation arises from the heritable acquisition of cell-type specific gene-expression programs. Key in understanding cellular specification is to elucidate the epigenetic mechanism that underlies transcriptional heterogeneity. Thus a central question in biology is how cell-to-cell variability in the epigenome contributes to the emergence of phenotypic differences. However, current tech ...
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 1

 TERMINÉ 
The project seeks to explore culinary practice among early farming European communities, from the Aegean to Central Europe, spanning the Neolithic through to the Iron Age (7th-1st millennia BC). The project seeks to identify the ‘food cultures’ of prehistoric Europe, and to reconstruct how cultivated and wild plant foods were transformed into dishes exploring their underlying cultural and environm ...
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 5

 TERMINÉ 
Gene expression is a highly dynamic and inherently variable process. Yet, it needs to be tightly regulated, especially during the cell cycle, when continuous large-scale changes occur to the proteome. Even small deviations in the expression levels of a single protein in individual cells can de-regulate cell cycle entry and promote tumorigenesis. Here, I will develop new technology to study gene ex ...
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 1

 TERMINÉ 

Behavioral and Policy Implications of Rational Inattention (INATTENTION)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,

This proposal outlines agenda which aims to improve our understanding of policies in environments with cognitively limited agents. It seeks to extend and apply the theory of rational inattention developed in macroeconomics. Citizens are inattentive to details of tax codes, government bureaucrats cannot inspect all data about people in need, and voters are highly uninformed about politicians’ campa ...
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 1

 TERMINÉ 
The main objectives of the 2nd Coordination and Support Action (CSA) of the Joint Programming Initiative Healthy Diet for a Healthy Life (JPI HDHL) are to support the further implementation of JPI HDHL and to create a sustainable collaboration of Member States (MS), the European Commission (EC) and related international organisations. Support facilitated by the 2nd CSA will ensure sufficient progr ...
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 11

 TERMINÉ 

Fuel and chemicals from lignin through enzymatic and chemical conversion (FALCON)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The transition to a biobased economy puts strong challenges on researchers and industry to develop sustainable processes. 2G biofuel plants use waste streams as substrates, but themselves generate a new waste stream of lignin-rich sludge that is left after saccharification of the carbohydrates. This waste stream is expected to exponentially increase with an increasing number of 2G bioethanol plant ...
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 9

 TERMINÉ 

Nanoporous and Nanostructured Materials for Medical Applications (NanoMed)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

This project aims to stimulate intersectoral and international collaboration within Europe and with an ICPC country, Kazakhstan, in the area of novel nanoporous and nanostructured adsorbents for the treatment of very serious health conditions associated with acute and chronic exposure to external radiation and uptake of heavy metals and radiation as a consequence of accidental, occupational or del ...
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 11

 TERMINÉ 
Experimentation in mesocosms is arguably the single most powerful approach to obtain a mechanistic quantitative understanding of ecosystem-level impacts of stressors in complex systems, especially when embedded in long-term observations, theoretical models and experiments conducted at other scales. AQUACOSM builds on an established European network of mesocosm research infrastructures (RI), the FP ...
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 23

 TERMINÉ 
The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society. The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is st ...
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 33

 TERMINÉ 

ACCELERATing Europe's Leading Research Infrastructures (ACCELERATE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

CERIC-ERIC (CERIC) is a distributed research infrastructure for fundamental and applied research on novel materials and biomaterials. The RI has been in operation for 2 years and provides open access to a broad range of instruments and expertise across research communities, in order to support the research community world-wide in tackling the most challenging problems of materials research. The A ...
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 8

 TERMINÉ 
FOIE GRAS provides innovative training for 13 early stage researchers (ESRs) to answer two critical and unanswered questions: a) Is hepatic bioenergetic remodelling involved in NAFLD pathogenesis, and target for stratification or therapeutic/lifestyle interventions? and b) Is the disruption of the gut-liver axis involved in NAFLD progression? In Western Societies, there has been a recent surge of ...
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 11

 TERMINÉ 
Environmental perturbations to lakes and reservoirs occur largely as episodic climatic events. These range from relatively short mixing events to storms and heat waves. While the driving events occur along a continuum of frequency and magnitude, however, their effect is generally longer lasting than the events themselves. In addition, the more extreme weather events are now becoming increasingly ...
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 8

 TERMINÉ 

Accelerators Validating Antimatter physics (AVA)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Antiprotons, stored and cooled at low energies in a storage ring or at rest in traps, are highly desirable for the investigation of basic questions on fundamental interactions, the static structure of antiprotonic atoms, CPT tests by high-resolution spectroscopy on antihydrogen, as well as gravity experiments. Antimatter experiments are at the cutting edge of science. They are, however, very diffi ...
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 11

 TERMINÉ 

INtestinal Tissue ENgineering Solution (INTENS)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Short Bowel Syndrome (SBS) is a condition that occurs when part or the entire small intestine is missing or has been removed during surgery. This condition renders the bowel incapable of fulfilling its nutritional function (intestinal failure). There is no cure for SBS. Parenteral (intravenous) nutrition (PN) and bowel transplantation are currently the preferred options for nutrition in children a ...
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 9

 TERMINÉ 

From Open to Closed Loop Optimal Control of PDEs (OCLOC)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

The proposal addresses some of the most pressing topics in optimal control of partial differential equations (PDEs): Non-smooth, non-convex optimal control and computational techniques for feedback control. These two topics will be applied to the large scale optimal control problems for the bidomain equations, which are the established model to describe the electrical activity of the heart. Due to ...
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 2

 TERMINÉ 

The Enigma of the Hyksos (Hyksos Enigma)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

The Hyksos (Greek rendering of the Egyptian title “rulers of the foreign countries”) were a dynasty of foreign rulers of Egypt between c.1640 and 1530 BC. Some modern researchers, following the ancient historian Flavius Josephus (1st cent. AD) thought they were ancestors of the early Israelites, others suggested that their appearance should be tied to the Hurrian expansion to the Levant. Most scho ...
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 2

 TERMINÉ 

Science Advice for Policy by European Academies (SAPEA)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,

The “Science Advice for Policy by European Academies” (SAPEA) project brings together the five European Academy Networks Academia Europaea, ALLEA, EASAC, Euro-CASE and FEAM. Through these networks, the SAPEA project pools the resources of around 100 individual academies with hundreds of Fellows each. While individual networks are specialised in certain scientific areas, the SAPEA project combines ...
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 6

 TERMINÉ 
We pioneered the essential role of Wnt signals in adult stem cells, i.e. in intestinal crypts. We also found that loss of the APC gene activates the Wnt pathway and causes colorectal cancer (CRC). We then identified a Wnt target gene, Lgr5, which allowed us to define the crypt stem cells. In a previous ERC grant based on these findings, we identified novel Lgr5 stem cells in multiple organs, and d ...
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 1

 TERMINÉ 
Major depression is among the most burdening health hazards. Its prevalence is 1-3%, an additional 8-16% have clinically significant symptoms, and prognosis is poor. Unfortunately, less than 20% of the cases are detected and treatment effectiveness is moderate. The Global Consortium for Depression Prevention stresses that our best chance to combat the global burden of depression is provide prevent ...
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 1

 TERMINÉ 
The Industrial Revolution is one of the most important events in human history: within a century, some countries multiplied their per capita income while others stagnated, exacerbating international inequality. Reducing this enduring inequality through industrial development has been a crucial policy goal; however, as no precise understanding of industrial development exists, no consistent interna ...
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 1

 TERMINÉ 

Tumor cell death supports recurrence of cancer (Cancer-Recurrence)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

Introduction: Current anti-cancer treatments are often inefficient, while many patients initially benefit from anti-cancer drugs eventually experience relapse of resistant tumors throughout the body. Current clinical strategies mainly aim at inducing tumor cell death, but this induction may have unintentional and unwanted side effects on surviving tumor cells.Preliminary data: We show that after c ...
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 1

 TERMINÉ 

Dicer-Dependent Defense in Mammals (D-FENS)

Date du début: 1 juil. 2015, Date de fin: 30 juin 2020,

Viral infection or retrotransposon expansion in the genome often result in production of double-stranded RNA (dsRNA). dsRNA can be intercepted by RNase III Dicer acting in the RNA interference (RNAi) pathway, an ancient eukaryotic defense mechanism. Notably, endogenous mammalian RNAi appears dormant while its common and unique physiological roles remain poorly understood. A factor underlying mamma ...
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 2

 TERMINÉ 

ULYSSES

Date du début: 1 juin 2016, Date de fin: 31 mai 2020,

The Ulysses project was originally inspired by an illustrious generation of 18th Century artists who wandered all across Europe, visiting at each “stop” along the way the greatest masters’ workshops in order to improve and to complete their skills. Following the steps of the Homeric hero, their odyssey was an initiatory journey paving the way for future generations of young European artists. Today ...
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 13

 TERMINÉ 
The basal ganglia consist of a set of neuroanatomical structures that participate in the representation and execution of action sequences. Dopamine neurotransmission in the striatum, the main input nucleus of the basal ganglia, is a fundamental mechanism involved in learning and regulation of such actions. The striatum has multiple functional units, where the limbic striatum is thought to mediate ...
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 2

 TERMINÉ 

Social Innovation in Marginalised Rural Areas (SIMRA)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2020,

SIMRA seeks to advance understanding of social innovation (SI) and innovative governance in agriculture, forestry and rural development (RD), and how to boost them, particularly in marginalised rural areas across Europe, with a focus on the Mediterranean region (including non-EU) where there is limited evidence of outcomes and supporting conditions. These objectives will be achieved by: 1. Develop ...
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 26

 TERMINÉ 
European aquaculture production provides direct employment to 80,000 people and a 3-billion € annual turnover. Parasites cause severe disease outbreaks and high economic losses in finfish aquaculture. The overarching goal of ParaFishControl is to increase the sustainability and competitiveness of European Aquaculture by improving understanding of fish-parasite interactions and by developing innova ...
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 31

 TERMINÉ 
European societies face rapid social changes, challenges and benefits, which can be studied with traditional tools of analysis, but with serious limitations. This rapid transformation covers changes in family forms, fertility, the decline of mortality and increase of longevity, and periods of economic and social instability. Owing to population ageing across Europe, countries are now the experienc ...
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 10

 TERMINÉ 

Generations and Gender Programme: Evaluate, Plan, Initiate (GGP-EPI)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

The Generations and Gender Programme (GGP) provides high quality cross-national, longitudinal data for the study of population change. The data provided by the GGP have been used by more than 3,000 researchers worldwide and have led to over 500 peer-reviewed journal articles. The data have provided insights into some of the most pressing societal challenges such as care for older persons, female e ...
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 9

 TERMINÉ 

HERA Joint Research Programme Uses of the Past (HERA JRP UP)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

AbstractThe HERA Joint Research Programme Uses of the Past (HERA JRP UP) consortium will establish a 3rd joint transnational programme for multi-disciplinary research into a topic at the heart of the reflective society: ”Uses of the Past”. The innovative projects funded will fundamentally link past(s), present and future(s) creating valuable new knowledge that gives insights into the forces shapin ...
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 26

 TERMINÉ 

Transnational Network of cooperation for WIDESPREAD NCPs (NCP_WIDE.NET)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

The objective of the NCP_WIDE.NET is to create a transnational network of National Contact Points (NCPs) for Spreading Excellence and Widening Participation under Horizon 2020 in order to facilitate trans-national co-operation between NCPs, with a view to identifying and sharing good practices and raising the general standards of support to applicants, taking into account the diversity of actors, ...
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 20

 TERMINÉ 
All visual information is broadcasted by an intra-retinal pathway formed by a group of neurons called bipolar cells. They collect photoreceptor signals in the outer retina and relay the signals to the inner retinal neurons. This transfer of visual information is far from passive: Each of the at least 10 bipolar cell types transforms the photoreceptor signals in a unique and highly specific way. As ...
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 11

 TERMINÉ 

Encouraging Lifelong Learning for an Inclusive and Vibrant Europe (ENLIVEN)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2019,

The ENLIVEN research models how policy interventions in adult education markets can become more effective. Integrating state-of-the-art methodologies and theorisations (e.g. Case-Based Reasoning methodology in artificial intelligence, bounded agency in adult learning), it implements and evaluates an innovative Intelligent Decision Support System to provide a new and more scientific underpinning fo ...
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 11

 TERMINÉ 

Building intercultural competencies for ambulance services

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

Intercultural competencies and a better understanding of each other are vital for the peaceful coexistence of humans in general and in Europe in particular. The BICAS project makes a valuable contribution. Through the ongoing European integration and also the growing numbers of immigrants in the EU the need for intercultural competencies in professions dealing directly with people is inevitable. ...
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 6

 TERMINÉ 
There are major changes within and related to the professional driving profession ahead of us that need to be prepared and supported by vocational education and training in order to reach its full potential but also to avoid a further increase of already today’s major deficits of skilled workers in this field that belonged continuously to the Top Ten jobs employers are having difficulty filling ov ...
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 6

 TERMINÉ 

Qualifications for third milenium in electrical engineering

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

Context of the project is based on cross-sectoral cooperation. It reacts to a newly emerging need that arose from the development of new technologies in the field of electromobility and smart grids and the need to reflect it and respond to it even in the education field. The objective of the project is to define and describe 5 education modules concerning electromobility and smart grids, educatio ...
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 8

 TERMINÉ 

Serious game to train experts in advanced multimodality

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

Multimodality as a concept can be described as an interdisciplinary approach enabling capitalising on a multiplicity of media and modes that will greatly benefit to educational institutions in the evolution of their learning methodologies. Indeed, with the development of new technologies, digital tools are more and more used in the educational sector. For instance, serious games are an innovative ...
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 5