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 EN COURS 

SEMMERING RAILWAY BASE TUNNEL

Date de fin: 30 déc. 2024,

Aim: Projects part of proposed Core Network and Baltic Adriatic Core Network corridorConstruction of two tube base tunnel
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 1

 TERMINÉ 

Belgian Nature Integrated Project (BNIP)

Date du début: 1 déc. 2015, Date de fin: 31 déc. 2023,

Background The Habitats Directive Article 17 and Birds Directive Article 12 report, published in 2007, revealed the unfavourable conservation status in Belgium of many habitats and species listed in these directives. The main drivers identified were inappropriate land use, low environmental quality, insufficient management and under-resourced conservation ...
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 6

 TERMINÉ 

Cross-border protection of the Great Bustard in Central Europe (LIFE Great Bustard)

Date du début: 11 juil. 2016, Date de fin: 31 déc. 2023,

Background Austria and Hungary have undertaken efforts to protect and enlarge the habitat of great bustards, a bird species listed in Annex I of the Birds Directive. They have focused on active habitat management and on the maintenance of large areas dedicated to non-intensive farming. But the problem of overhead power lines remains great, causing fatal c ...
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 10

 TERMINÉ 

Stepping stones towards ensuring long-term favourable conservation status of Aquatic warbler in Lithuania (LIFEMagniDucatusAcrola)

Date du début: 7 juil. 2016, Date de fin: 31 janv. 2023,

Background The aquatic warbler (Acrocephalus paludicola) is Europe’s rarest migratory songbird and a globally threatened species (listed as ‘vulnerable’ by the IUCN and included in Annex I of the EU Birds Directive). It has very specific habitat requirements, being found only on fen mires or wet meadows on peaty soil covered by sedges. The water lev ...
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 5

 TERMINÉ 

Crimean-Congo Haemorrhagic Fever Vaccine (CCHFVaccine)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2022,

Natural epidemics and outbreaks of emerging viral epidemics are growing problems internationally. The general aim of the CCHFVaccine project is to develop and deliver a vaccine, which can significantly increase our capacity to control the situation of Crimean Congo Haemorrhagic fever (CCHF) disease on a global basis. The proposed work program on CCHF virus aims to build a multidisciplinary researc ...
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 15

 TERMINÉ 

Towards integrated management of freshwater Nature 2000 sites and habitats (FRESHABIT)

Date du début: 1 janv. 2016, Date de fin: 30 sept. 2022,

... Freshwater habitats are among the most threatened habitat types globally. In the 2007-2012 conservation status assessment of the EU Habitats Directive (Article 17), none of the freshwater, coastal, and groundwater dependent wetland habitats in Europe fully met favourable conservation status, and most are in unfavourable conservation status. Almost 50% of European water bodies are failing to achi ...
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 30

 TERMINÉ 

Investigating Host-Microbial Interactions after Bariatric Surgery (EnteroBariatric)

Date du début: 1 août 2017, Date de fin: 31 juil. 2022,

Obesity and related co-morbidities give rise to severe health and socioeconomic problems. Surgical treatment for obesity (bariatric surgery) is remarkably effective in the control of morbid obesity and rapid resolution of Type 2 Diabetes, and the number of such procedures is increasing rapidly in many obesity-prevalent countries. We, and others, have demonstrated that surgical interventions such a ...
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 2

 TERMINÉ 

Bright Future for Black Vulture in Bulgaria (Vultures back to LIFE)

Date du début: 16 juil. 2015, Date de fin: 15 juil. 2022,

Background The most serious problem for vultures in Bulgaria today is the critically low number of populations and their isolation. In spite of two decades of conservation efforts, the WWF Greece Dadia project showed that the number of breeding pairs is not increasing and remains around 20 pairs. Another threat is unsuitable livestock breeding practices r ...
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 5

 TERMINÉ 

Hydrogen Mobility Europe 2 (H2ME 2)

Date du début: 1 mai 2016, Date de fin: 30 juin 2022,

...s to address the innovations required to make the hydrogen mobility sector truly ready for market. The project will perform a large-scale market test of hydrogen refuelling infrastructure, passenger and commercial fuel cell electric vehicles operated in real-world customer applications and demonstrate the system benefits generated by using electrolytic hydrogen solutions in grid operations.H2ME 2 ...
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 37

 TERMINÉ 

A Systems medicine approach to chronic inflammatory disease (SYSCID)

Date du début: 1 janv. 2017, Date de fin: 31 mars 2022,

...rediction in CID. We will focus on three major CID indications with distinct characteristics, yet a large overlap of their molecular risk map: inflammatory bowel disease, systemic lupus erythematodes and rheumatoid arthritis. We have joined 15 partners from major cohorts and initiatives in Europe (e.g.IHEC, ICGC, TwinsUK and Meta-HIT) to investigate human data sets on three major levels of resolut ...
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 16

 TERMINÉ 

Conservation of the eastern imperial eagle by decreasing human-caused mortality in the Pannonian Region (PannonEagle Life)

Date du début: 1 oct. 2016, Date de fin: 31 mars 2022,

...80s, the Hungarian population of the eastern imperial eagle has come back from the brink of extinction, reaching 160 pairs by 2014. The Pannonian biogeographical region (which includes all of Hungary and parts of Slovakia, Romania, Czech Republic, Croatia, Serbia and Ukraine) now holds some 220 pairs of this priority raptor species (Annex 1 of the EU Birds Directive). However, this small populatio ...
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 12

 TERMINÉ 

Biophysics and circuit function of a giant cortical glutamatergic synapse (GIANTSYN)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2022,

...ntal question in neuroscience is how the biophysical properties of synapses shape higher network computations. The hippocampal mossy fiber synapse, formed between axons of dentate gyrus granule cells and dendrites of CA3 pyramidal neurons, is the ideal synapse to address this question. This synapse is accessible to presynaptic recording, due to its large size, allowing a rigorous investigation of ...
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 1

 TERMINÉ 

Prevalence and Influence of Sexual Antagonism on Genome Evolution (SexAntag)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2022,

Males and females display profound differences in phenotype, physiology and behavior, and understanding the evolutionary forces driving this diversity is a long-standing goal in evolutionary biology. Sexually antagonistic conflict, resulting from traits and/or mutations that are beneficial to one sex but harmful to the other, can in theory lead to strong dimorphism, and has been invoked to explain ...
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 1

 TERMINÉ 

Restoration and management of Danube floodplain habitats (LIFE Danube floodplains)

Date du début: 1 août 2015, Date de fin: 31 janv. 2022,

Background In past 200 years, the water and wetland habitats of the Danube region have undergone great change: dams have been constructed; flood protection introduction; navigation improved; agricultural and forestry activities intensified; and land drained. Large continuous flood areas have been reduced and divided by dykes, while numerous branches have ...
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 5

 TERMINÉ 

MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and Modeling (MATERIALIZABLE)

Date du début: 1 févr. 2017, Date de fin: 31 janv. 2022,

While access to 3D-printing technology becomes ubiquitous and provides revolutionary possibilities for fabricating complex, functional, multi-material objects with stunning properties, its potential impact is currently significantly limited due to the lack of efficient and intuitive methods for content creation. Existing tools are usually restricted to expert users, have been developed based on th ...
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 1

 TERMINÉ 

Seafaring Lives in Transition. Mediterranean Maritime Labour and Shipping during Globalization, 1850s-1920s. (SeaLiT)

Date du début: 1 févr. 2017, Date de fin: 31 janv. 2022,

SeaLiT explores the transition from sail to steam navigation and its effects on seafaring populations in the Mediterranean and the Black Sea between the 1850s and the 1920s. In the core of the project lie the effects of technological innovation on seafaring people and maritime communities, whose lives were drastically altered by the advent of steam. The project addresses the changes through the ac ...
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 1

 TERMINÉ 

GEOTHERMICA - ERA NET Cofund Geothermal (GEOTHERMICA)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Europe is challenged to increase the share of renewable energy for heating and cooling, industrial processes, power generation and energy storage. Geothermal energy is a vastly under-utilized indigenous, clean, low footprint and continuously available energy resource, and thus uniquely positioned to substantially contribute to a safe and secure energy supply of Europe’s Energy Union. Hitherto only ...
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 18

 TERMINÉ 

MacroAutophagy and Necrotic Neurodegeneration in Ageing (MANNA)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Necrosis contributes critically in devastating human pathologies such as stroke, ischemia, and age-associated neurodegenerative disorders. Ageing increases susceptibility to neurodegeneration, in diverse species ranging from the lowly nematode Caenorhabditis elegans to humans. The mechanisms that govern necrotic neurodegeneration and its modulation by ageing are poorly understood. Autophagy has be ...
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 1

 TERMINÉ 

Federation for FIRE Plus (Fed4FIREplus)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The Fed4FIRE+ project has the objective to run and further improve Fed4FIRE’s “best-in-town” federation of experimentation facilities for the Future Internet Research and Experimentation initiative. Federating a heterogeneous set of facilities covering technologies ranging from wireless, wired, cloud services and open flow, and making them accessible through common frameworks and tools suddenly op ...
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 24

 TERMINÉ 

Establishing the European Geological Surveys Research Area to deliver a Geological Service for Europe (GeoERA)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The GeoERA proposal is put forward by the national and regional Geological Survey Organisations (GSO) of Europe. Its overall goal is to integrate the GSO’s information and knowledge on subsurface energy, water and raw material resources, to support sustainable use of the subsurface in addressing Europe’s grand challenges. The GeoERA consortium will organise and co-fund together with the EC a joint ...
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 45

 TERMINÉ 

Healthy minds from 0-100 years: Optimising the use of European brain imaging cohorts (Lifebrain)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Our main objective is to identify determinants of brain, cognitive and mental health at different stages of life. By integration, harmonisation and enrichment of major European neuroimaging studies of age differences and changes, we will obtain an unparalleled database of fine-grained brain, cognitive and mental health measures of more than 6.000 individuals. Longitudinal brain imaging, genetic an ...
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 16

 TERMINÉ 

Development of Effective Vaccines against Multiple Lifecycle Stages of Plasmodium vivax malaria (MultiViVax)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Plasmodium vivax is the most widespread malaria and constitutes a significant proportion of human malaria cases. P. vivax accounts for 100-400 million clinical cases each year among the 2.5 billion people living at risk in Latin America, Oceania and Asia. The recently revised Malaria Vaccine Technology Roadmap to 2030 recognises the severity of P. vivax malaria and calls for a vaccine intervention ...
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 9

 TERMINÉ 

European Human Biomonitoring Initiative (HBM4EU)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The overarching goal of the European Human Biomonitoring Initiative (HBM4EU) is to generate knowledge to inform the safe management of chemicals and so protect human health. We will use human biomonitoring to understand human exposure to chemicals and resulting health impacts and will communicate with policy makers to ensure that our results are exploited in the design of new chemicals policies an ...
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 43

 TERMINÉ 

Optimizing a deployable high efficacy malaria vaccine (OptiMalVax)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

A highly effective malaria vaccine against Plasmodium falciparum should help prevent half a million deaths from malaria each year. New vaccine technologies and antigen discovery approaches now make accelerated design and development of a highly effective multi-antigen multi-stage subunit vaccine feasible. Leading malariologists, vaccine researchers and product developers will here collaborate in ...
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 17

 TERMINÉ 

Fostering responsive mental health systems in the Syrian refugee crisis (STRENGTHS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

STRENGTHS aims to provide effective community-based health care implementation strategies to scale-up the delivery and uptake of effective mental health interventions in different country contexts. The current refugee crisis across Europe and the Middle East effects both individual refugees’ psychological well-being, as they face extreme stressors in their flight from their home country, but also ...
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 15

 TERMINÉ 

Strengthening management at district level to support the achievement of Universal Health Coverage (PERFORM2scale) (Perform 2 scale)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

...rs. The PERFORM project developed a problem-based management strengthening intervention for management teams at district level in three African countries to improve both health workforce performance and service delivery more generally. The evaluation of the management strengthening intervention (MSI) demonstrated its effectiveness in enabling the management teams to solve workforce performance an ...
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 7

 TERMINÉ 

EUROlinkCAT: Establishing a linked European Cohort of Children with Congenital Anomalies (EUROlinkCAT)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Over 130,000 children born in Europe every year will have a congenital anomaly (CA; birth defect). These CAs, which are often rare diseases, are a major cause of infant mortality, childhood morbidity and long-term disability. EUROCAT is an established European network of population-based registries for the epidemiologic surveillance of CAs. EUROlinkCAT will use the EUROCAT infrastructure to suppor ...
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 25

 TERMINÉ 

Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine (MultipleMS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The complex interactions between genetic and non-genetic factors produce heterogeneities in patients as reflected in the diversity of pathophysiology, clinical manifestations, response to therapies, disease development and progression. Yet, the full potential of personalized medicine entails biomarker-guided delivery of efficient therapies in stratified patient populations.MultipleMS will therefor ...
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 25

 TERMINÉ 

Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial (PAPA-ARTIS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in ...
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 26

 TERMINÉ 

Restoration of sterlet populations in the Austrian Danube (LIFE Sterlet)

Date du début: 1 sept. 2015, Date de fin: 31 déc. 2021,

Background The sterlet (Acipenser ruthenus) is the smallest species of the Danube sturgeons and resides for its whole lifecycle in freshwater without the need to migrate to the Black Sea. Sterlets are still present in very small quantities in the Upper Danube whereas the large anadromous sturgeon species became extinct in the last century due to overfishi ...
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 3

 TERMINÉ 

Recovering and securing the future of the globally Near Threatened black-tailed godwit (Limosa limosa) in the UK (LIFE blackwit UK)

Date du début: 1 août 2016, Date de fin: 31 déc. 2021,

Background The black-tailed godwit (Limosa limosa) is categorised as “near threatened” in the IUCN Red List, and is one of the fourteen UK breeding birds that are of global conservation concern. It is classified as “vulnerable” in Europe and “endangered” in the EU – making it one of only 27 bird species that are “endangered” or “critic ...
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 2

 TERMINÉ 

Brain-Specific, Modular and Active RNA Therapeutics (B-SMART)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The overall objective of B-SMART is: 1. to design modular nanoparticles, 2. to manufacture them via a quality-by-design protocol, 3. to achieve delivery of therapeutic RNAs to the brain and treat neurodegenerative diseases. I. To design modular nanoparticles consisting of o an active RNA payloado established (lipid-based), emerging (trigger-responsive polymer-based) or exploratory (extracellular v ...
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 9

 TERMINÉ 

Tackling Water Challenges in the International Context (IC4WATER)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

... Programming Initiative Water Challenges for a Changing World, the Water JPI, is an intergovernmental initiative which strives to achieve sustainable water systems for a sustainable economy in Europe and abroad.IC4WATER’s objectives include supporting agencies in stepping up international cooperation: through the sharing of best practices, networking, closer coordination of existing activities, an ...
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 19

 TERMINÉ 

The Birth of Party Democracy. The Emergence of Mass Parties and the Choice of Electoral Laws in Europe and North America (1870-1940) (partydemocracy)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The project will develop a theoretically-based account of the emergence of mass parties, the choice of electoral institutions, and the final crystallization of different party systems in Europe and North America during the emergence of mass democracy and the formation of modern parties (1870-1940). It will combine statistical and historical methods to explain the formation of diverse party systems ...
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 1

 TERMINÉ 

Power of Algorithms in Discrete Optimisation (PowAlgDO)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Convex relaxations, such as linear and semidefinite programming, constitute one of the most powerful techniques for designing efficient algorithms, and have been studied in theoretical computer science, operational research, and applied mathematics. We seek to establish the power convex relaxations through the lens of, and with the extensions of methods designed for, Constraint Satisfaction Proble ...
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 1

 TERMINÉ 

Topographically-driven meteoric groundwater – An important geomorphic agent (MARCAN)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

...ecause sea level has been lower than at present for 80% of the last 2.6 million years. Groundwater has been implicated as an important agent in the geomorphic evolution of passive continental margins and the canyons that incise them. However, the geomorphic efficacy of groundwater remains dubious, and a diagnostic link between landscape form and groundwater processes remains poorly quantified, esp ...
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 3

 TERMINÉ 

Global Methods in the Langlands Program (GMLP)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The Langlands program is a conjectural framework for understanding the deep relations between automorphic forms and arithmetic. It implies a parameterization of representations of Galois groups of (local or global) fields in terms of representations of (p-adic or adelic) reductive groups. While making progress in the Langlands program often means overcoming significant technical obstacles, new res ...
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 1

 TERMINÉ 

Combatting Bacterial Resistance in Europe - Molecules against Gram Negative Infections (COMBACTE-MAGNET)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2021,

Antimicrobial resistance (AMR) is a major global public health threat, and most troublesome is the rapid emergence and dissemination of multidrug resistant (MDR) Enterobacteriaceae, Acinetobacter species and Pseudomonas aeruginosa. There is an unmet medical need to prevent P. aeruginosa infection in critically ill patients and to develop new antibiotics for infections caused by Gram-negative bacte ...
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 44

 TERMINÉ 

ERA-Net Cofund on Sustainable Food production and consumption (SUSFOOD2) (SUSFOOD2)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The aim of SUSFOOD2 is to foster research and innovation in the field of sustainable food systems through enhanced cooperation and coordination between EU member and associated states. It will thereby contribute to the overall EU objective of building the European Research Area as well as a newly emerging Food Research Area. Major challenges will influence future food chains asking for innovative ...
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 26

 TERMINÉ 

Functional Systems of Capsules (FunCapSys)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

...organism is composed of myriad chemical subsystems, each consisting of structurally complex biomolecules that interact in many ways; the properties of life emerge from these dense connections. Understanding how these interactions take place will help elucidate the foundations of biology, as well as enabling the design and creation of new chemical networks with targeted functions. Deciphering and d ...
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 1