3 projets européens trouvés
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TERMINÉ
Nanotherapeutics for antibiotic resistant emerging bacterial pathogens (NAREB)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
Increase in antibiotic resistance is a global concern worldwide. The project NAREB's main objective is the optimization of several nanoformulations of antibacterial therapeutics in order to improve the therapy of multi-drug resistant (MDR) tuberculosis (TB) and MRSA infections in European MDR patients.NAREB will address the problem of drug bioavailability inside the infected macrophages, transport ...
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16
Participants partenaires
TERMINÉ
Anti-Parasitic Drug Discovery in Epigenetics (A-PARADDISE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,
This proposal builds on the proven methodology developed in the SEtTReND FP7 project to develop inhibitors of schistosome HME as lead compounds for new drugs. We will employ a target-based strategy for the development of novel drug leads against schistosomiasis, leishmaniasis, Chagas disease and malaria by targeting histone modifying enzymes (HME), in particular those involved in acetylation/deace ...
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16
Participants partenaires
TERMINÉ
DElineation of Striato-CoRtical contrIbutions to BEhavioral symptoms in FrontoTemporal Dementia (DESCRIBE-FTD)
Date du début: 1 oct. 2014, Date de fin: 30 sept. 2016,
Second to Alzheimer’s disease (AD) in prevalence, frontotemporal dementia (FTD) is a neurodegenerative condition resulting from the progressive deterioration of the frontal and temporal lobes of the brain. Cognitive and behavioural impairments are the most early and prevalent characteristic of FTD. In numerous studies, these disturbances have been related to cortical atrophy, but recent findings s ...
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