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Plus de 40 projets européens trouvés

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 TERMINÉ 

European Gram Negative Antibacterial Engine (ENABLE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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 42

 TERMINÉ 

NEXUS 1492. New World Encounters in a Globalising World (NEXUS1492)

Date du début: 1 sept. 2013, Date de fin: 31 août 2019,

NEXUS1492 investigates the impacts of colonial encounters in the Caribbean, the nexus of the first interactions between the New and the Old World. This Synergy Programme intends to rewrite a crucial and neglected chapter in global history initiated by European colonisation by focussing on transformations to indigenous, Amerindian cultures and societies. NEXUS1492 will address intercultural Amerind ...
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 3

 TERMINÉ 

Biology of UnderGround Symbioses (BUGS): studies of a subterranean ant-aphid-microbe cooperative network (BUGS)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2017,

Mutualism, cooperative interaction between different species, is widespread in nature. Despite its ubiquity and recognised importance for ecological communities, how mutualism evolves and persists remain major unresolved questions in evolutionary biology. The reason for this is that mutualistic interactions can often be exploited by parasites, and high degrees of species interdependence can increa ...
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 1

 TERMINÉ 

Global Earth Observation for integrated water resource assessment (eartH2Observe)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

The project eartH2Observe brings together the findings from European FP projects DEWFORA, GLOWASIS, WATCH, GEOWOW and others. It will integrate available global earth observations (EO), in-situ datasets and models and will construct a global water resources re-analysis dataset of significant length (several decades). The resulting data will allow for improved insights on the full extent of availab ...
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 27

 TERMINÉ 

European Lead Factory (EUC²LID)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
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 34

 TERMINÉ 

Next Zero Energy Buildings at lowest Cost by using Competitive Sustainable Technology (NEXT-BUILDINGS)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,

This project is about the demonstration of very low energy buildings. In all demonstrations, the ambition is net zero carbon/energy or better (active or plus-energy house). The project paves the way for large scale implementation of energy neutral buildings/neighbourhoods as foreseen in the Energy Performance of Buildings directive and the pilots are running more than five years ahead of the goal ...
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 14

 TERMINÉ 

"Land use change: assessing the net climate forcing, and options for climate change mitigation and adaptation" (LUC4C)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

"LUC4C will advance our fundamental knowledge of the climate change - land use change interactions, and develop a framework for the synthesis of complex earth system science into guidelines that are of practical use for policy and societal stakeholders.Policies in support of climate change mitigation through land management, and the societal demand for other services from terrestrial ecosystems ar ...
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 15

 TERMINÉ 

High-End cLimate Impacts and eXtremes (HELIX)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

"With the target of limiting global warming to 2ºC increasingly difficult to achieve, policymakers, businesses and other decision-makers need to plan to adapt to changes in climate under higher levels of global warming. This requires coherent information on the future climate conditions, and the consequences of different adaptation actions. International negotiations on limiting global warming a ...
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 17

 TERMINÉ 

The biogenesis of tail-anchored membrane proteins: knowledge and exploitation (TAMPTING)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

Even in the simplest cells, the integration of proteins into a biological membrane is a complex process that is frequently coupled to ribosomal protein synthesis, and requires the coordinated actions of several additional cellular machines. The de novo recapitulation of such a complex process is well beyond the scope of our current technical abilities. Indeed, the techniques that are used to creat ...
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 8

 TERMINÉ 

Deciphering inter- and intracellular signalling in schizophrenia (IN-SENS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

IN-SENS is an interdisciplinary, cutting-edge European industry-academia collaborative effort for a novel training of scientists in molecular psychiatry with the prospect of discovering the biology of schizophrenia and actively promote drug discovery. Mental illnesses are a major burden to patients, relatives, and public health worldwide. IN-SENS therefore aims to profoundly change the academic-in ...
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 16

 TERMINÉ 

Multilevel brain network analyses leading to improved therapeutics for cognitive impairments (CognitionNet)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

Cognitive abilities change with development and age. Cognitive development during childhood and adolescence depends on an intellectually challenging environment, but is robustly affected in various forms of mental retardation. Adult cognitive abilities are strongly correlated with a person’s success in life. Finally, cognitive decline is an important problem during aging and is accelerated in neur ...
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 1

 TERMINÉ 

SUSTAINABLE NANOTECHNOLOGIES (SUN)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2017,

SUN (Sustainable Nanotechnologies) is the first project addressing the entire lifecycle of nanotechnologies to ensure holistic nanosafety evaluation and incorporate the results into tools and guidelines for sustainable manufacturing, easily accessible by industries, regulators and other stakeholders. The project will incorporate scientific findings from over 30 European projects, national and inte ...
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 38

 TERMINÉ 

A European Training Network for Sustainable Phosphorus Chemistry (SusPhos)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

The SusPhos training network will bring about a paradigm shift in the teaching of sustainable phosphorus chemistry, in the training of multidisciplinary-competent scientists, and in the public’s view on chemistry to preserve the essential element phosphorus from depletion. SusPhos represents the first systematic investigation of the eco-friendly production, smart use, recycling and commercial expl ...
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 14

 TERMINÉ 

Mechanism-Based Integrated Systems for the Prediction of Drug-Induced Liver Injury (MIP-DILI)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,

The current test systems employed by Industry are poorly predictive for Drug induced liver injury (DILI). The ‘MIP-DILI’ project will address this situation by the development of innovative preclinical test systems which are both mechanism-based and of physiological, pharmacological and pathological relevance to DILI in humans. An iterative, tiered approach with respect to test compounds, test sys ...
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 29

 TERMINÉ 

Integrating bioinformatics and chemoinformatics approaches for the development of expert systems allowing the in silico prediction of toxicities (ETOX)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2016,

The eTOX consortium proposes to develop innovative methodological strategies and novel software tools to better predict the toxicological profiles of new molecular entities in early stages of the drug development pipeline. This will be achieved by coordinating the efforts of specialists from academia and SMEs in the wide scope of disciplines that are required to move towards a more reliable modell ...
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 30

 TERMINÉ 

ADVANCED TOOLS FOR EXPOSURE ASSESSMENT AND BIOMONITORING (A-TEAM)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"A-TEAM is a major co-ordinated supradisciplinary study. It seeks to develop understanding of a variety of aspects related to external and internal exposure to selected chemicals using a single, well-characterised human cohort (the “A-TEAM”). Its overriding hypothesis is that current approaches used to monitor human exposure to consumer chemicals can be substantially improved by filling gaps in sc ...
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 9

 TERMINÉ 

Advanced Multidisciplinary Training in Molecular Bacteriology (AMBER)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"The advancement in life sciences has created a growing number of disciplines that are required to elucidate the increasingly complicated biological questions. This has led to an unsurpassed level of knowledge, but it has also resulted in a continuous specialization in PhD trainings, which makes the students less prepared for complex present day biological questions. To provide a better comprehens ...
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 9

 TERMINÉ 

NORA - Nitrous Oxide Research Alliance Training Network (NORA)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

The fate of anthropogenic nitrogen is at the core of our environmental predicament. Human activities have more than doubled the annual input of reactive nitrogen to the biosphere compared to prehistoric levels, causing escalating emissions of nitrous oxide (N2O) which contributes to global warming and depletion of stratospheric ozone. Ultimately, anthropogenic nitrogen will return to the atmospher ...
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 11

 TERMINÉ 

Phonon-Assisted Processes for Energy Transfer and Sensing (PAPETS)

Date du début: 1 sept. 2013, Date de fin: 30 nov. 2016,

There is mounting experimental and theoretical evidence that suggests that coherent electronic and vibrational dynamics are essential to understand physiological processes. This project addresses this newly emerging frontier between biology and quantum physics by aiming to determine the role of coherent vibrational dynamics in the efficiency of energy storage in natural and artificial light harves ...
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 8

 TERMINÉ 

Sustainable futures for Europe’s HERitage in CULtural landscapES: Tools for understanding, managing, and protecting landscape functions and values (HERCULES)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2016,

European cultural landscapes are valued as everyday living environment, countryside, heritage, scenery with aesthetic and recreational qualities and unique biodiversity, and as a source of ecosystem services that they provide to society. Cultural landscapes, however, are undergoing rapid and fundamental transformations across Europe, mainly as a result of an on-going polarization of land use, with ...
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 15

 TERMINÉ 

Quantum Chemistry of Enzymatic Nucleophilic Substitution: Untangling the Role of Metal Ions and Protein Environment in Biochemical Nucleophilic Substitution at Phosphorus and Sulfur (CompEnz)

Date du début: 1 nov. 2014, Date de fin: 31 oct. 2016,

Enzymatic nucleophilic substitution reactions are ubiquitous as key steps in biochemical processes of living cells. Despite their importance, they are poorly understood, in particular regarding the exact mechanism and involvement of the protein environment and the role and mechanistic involvement of metal ions. Through interpretative methods from chemical reactivity theory, I will tackle the miss ...
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 1

 TERMINÉ 

Responses to coastal climate change: Innovative Strategies for high End Scenarios -Adaptation and Mitigation- (RISES-AM-)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,

"Coastal areas concentrate vulnerability to climate change due to high levels of population, economic activity and ecological values. Because of that RISES-AM- addresses the economy-wide impacts of coastal systems to various types of high-end climatic scenarios (including marine and riverine variables). It encompasses analyses from global to local scales across the full range of RCPs and SSPs. It ...
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 12

 TERMINÉ 

Transitioning towards Urban Resilience and Sustainability (TURAS)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,

The “TURaS” project aims to bring together urban communities, researchers, local authorities and SMEs to research, develop, demonstrate and disseminate transition strategies and scenarios to enable European cities and their rural interfaces to build vitally-needed resilience in the face of significant sustainability challenges. To ensure maximum impact, the TURaS project has developed an innovati ...
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 34

 TERMINÉ 

Economics of climate change adaptation in Europe (ECONADAPT)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

The aim of the ECONADAPT project is to provide user-orientated methodologies and evidence relating to economic appraisal criteria to inform the choice of adaptation actions using analysis that incorporates cross-scale governance under conditions of uncertainty. A critical theme of the proposal is therefore to support the application of adaptation economics in the period following the publication o ...
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 14

 TERMINÉ 

Optimisation of Integrated Solid Waste Management Strategies for the Maximisation of Resource Efficiency (WASTECOSMART)

Date du début: 1 sept. 2013, Date de fin: 31 août 2016,

WASTECOSMART - Optimisation of Integrated Solid Waste Management Strategies for the Maximisation of Resource Efficiency addresses the priority areas of a “Resource Efficient Europe” and relates to the EcoAP, by boosting innovation based on research and technology development within the field of integrated waste management. Through cross border cooperation and collaborative research activities betw ...
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 22

 TERMINÉ 

The evolution of beneficial bacterial symbiosis (SYMBIO MUTUAL EVO)

Date du début: 15 mai 2014, Date de fin: 14 mai 2016,

Diverse bacterial lineages form beneficial relationships with hosts. Identifying the conditions under which relationships with symbiotic microbes stabilize or breakdown is key to understanding the major evolutionary transitions that have arisen from two species joining to form a new higher-level organism.Theory predicts that bacterial mutualism is maintained when partners provide reciprocal fitnes ...
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 1

 TERMINÉ 

Rosetta s Way Back to the Source: Towards Reverse Engineering of Complex Software (ROSETTA)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2016,

We propose a research program (Rossetta) towards reverse engineering of complex software that is available only in binary form. Most of the commercial software industry assumes that compilation (the translation of source code to binary code), is irreversible in practice for real applications. The research question for Rosetta is whether this irreversibility assumption is reasonable. If successful, ...
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 2

 TERMINÉ 

Time-dependent density functional theory for strongly-interacting electrons (TD-SCDFT)

Date du début: 1 avr. 2014, Date de fin: 31 mars 2016,

This proposal aims at developing a new theoretical framework for the description of quantum transport and optical properties of strongly-correlated many-electron systems. The project is based on the exact infinite-coupling-strength limit of density functional theory (DFT), the so-called Strictly-Correlated-Electron (SCE) functional, which has been largely developed by the host scientist for ground ...
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 1

 TERMINÉ 

Earth system Model Bias Reduction and assessing Abrupt Climate change (EMBRACE)

Date du début: 1 nov. 2011, Date de fin: 29 févr. 2016,

EMBRACE brings together the leading Earth System Models (ESMs) in Europe around a common set of objectives to improve our ability to (i) simulate the Earth System and (ii) make reliable projections of future global change. EMBRACE builds on the existing European collaboration network in Earth System Modelling and will be the main European input to international efforts in this field over the comin ...
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 20

 TERMINÉ 

Global Lakes Sentinel Services (GLASS)

Date du début: 1 mars 2013, Date de fin: 29 févr. 2016,

The Global Lakes Sentinel Services project will set up a system that is able to handle large quantities of Sentinel 2 and 3 data. The focus will be on the ingestion, archiving, pre-processing and distribution of data and results in a harmonized and user friendly way. The GLaSS system will have innovative functionalities for integrated use of Sentinel 2 and 3 data, time series generation, data mini ...
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 8

 TERMINÉ 

Integrated non-CO2 Greenhouse gas Observing System (INGOS)

Date du début: 1 oct. 2011, Date de fin: 31 déc. 2015,

InGOS will support and integrate the observing capacity of Europe for non-CO2 greenhouse gases (NCGHG: CH4, N2O, SF6, H2 and halocarbons). The emissions of these gases are very uncertain and it is unknown how future climate change will feedback into the land use coupled emissions of CH4 and N2O. The NCGHG atmospheric abundances will increase further in the future and the emissions of these gases a ...
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 39

 TERMINÉ 

Developmental neurotoxicity assessment of mixtures in children (DENAMIC)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

Various recent epidemiological studies have indicated that exposure to low doses of environmental biologically active contaminants during human development can alter gene expression and have deleterious effects on cognitive development in childhood. The DENAMIC project is ultimately focused on reducing such effects of environmental contamination on learning and developmental disorders in children. ...
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 18

 TERMINÉ 

ICOS improved sensors, network and interoperability for GMES (ICOS-INWIRE)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,

The fundamental objective of the ICOS-INWIRE project is to enhance the capabilities of the ICOS infrastructure and fill in critical gaps for monitoring fluxes and concentrations of greenhouse gases, in order to meet the needs of operational users in the GMES program. It will achieve this by: Developing and testing autonomous sensors systems for greenhouse gas fluxes and concentration, enhancing th ...
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 9

 TERMINÉ 

Joint Programming Initiative Connecting Climate Knowledge for Europe - Coordination and Support Action (JPI CLIMATE CSA)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,

The overall objective of this Coordination and Support Action is to coordinate and support the development and the implementation plans of the Joint Programming Initiative ‘Connecting Climate Knowledge for Europe’ (JPI Climate). The CSA will serve as a tool integrated in JPI Climate to enable it to address the challenges of climate change. Hence, it will contribute to the EU objective of building ...
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 18

 TERMINÉ 

Dissecting a minimal genome: a physical investigation of DNA transactions in mitochondria (PHYSGENE)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

I propose to unravel parts of the mechanochemistry of two key genome transactions: replication and transcription using an array of single-molecule techniques. To this end, I propose to study the minimal genomic machinery of mitochondria. Mitochondria are organelles in eukaryotic cells that contain their own DNA (mtDNA). Significant understanding of the biochemistry of DNA transactions in mitochond ...
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 2

 TERMINÉ 

Systems Networks Norms (SYSNORM)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,

Genomic sciences are driving progress in biology at an unprecedented pace, most recently through third-generation sequencing and synthetic biology. These achievements challenge commonly accepted biological concepts and assumptions in the humanities. In this Fellowship I will investigate the impact of genomic sciences on theory development in the social and human sciences, with focus on philosophy ...
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 4

 TERMINÉ 

The Integrated Initiative of European Laser Research Infrastructures III (LASERLAB-EUROPE)

Date du début: 1 juin 2012, Date de fin: 30 nov. 2015,

LASERLAB-EUROPE III is the European Consortium of major Laser Research Infrastructures, forming a FP7 Integrated Infrastructure Initiative. Geographically it covers the majority of European member states, following recent efforts to include partners from all over Europe 27. Scientifically, it covers many areas of laser science and applications with particular emphasis on short-pulses and high-inte ...
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 26

 TERMINÉ 

Introducing stacking and halogen bonding effects into ligand-target interaction energy calculations (IMPSCORE)

Date du début: 15 mai 2013, Date de fin: 14 nov. 2015,

The subject of the present proposal is computational chemistry with specific aim to incorporate certain interactions into docking calculations. The docking technique helps the design and synthesis of efficient pharmaceuticals that act via ligand–receptor interactions. In the frame of the project, new scoring function (SF) term(s) will be introduced for selected interactions (π – π stacking and hal ...
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 1

 TERMINÉ 

Strictly-correlated Density Functional Theory: methodology development and application to semiconductor nanostructures and ultracold atom gases (SCDFT)

Date du début: 1 mars 2013, Date de fin: 1 nov. 2015,

"This project has two main objectives: First, to further develop and generalize the formalism of strictly-correlated Density Functional Theory (SC DFT), which is ideally suited for the study of strongly-interacting systems. Second, to apply it to the study of both semiconductor nanostructures and ultracold atom gases. This novel methodology was recently proposed by the head scientist of the projec ...
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 1

 TERMINÉ 

Changing Permafrost in the Arctic and its Global Effects in the 21st Century (PAGE21)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

Permafrost is defined as ground that remains continuously at or below 0°C for at least two consecutive years; some 24% of the land surface in the northern Hemisphere is classified as permafrost. In the Northern high latitudes, strong warming has been observed over the recent decades, and climate models project strong future warming. A projected decline in the extent of permafrost will have a major ...
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 20