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Nano-technology enabled repositioning of Disulfiram as an anti-cancer stem cell agent (NANODISCAN)
Date du début: 5 juin 2014, Date de fin: 4 juin 2016,
Most cancers remain ‘incurable’ and life-thretening. Cancer stem cells (CSCs) are the source of chemo/radioresistance and responsible for cancer recurrence which suggests the urgent requirement of CSC-targeting drugs. Drug development is a slow (15 years/drug) and costly (US$1.5bn/drug) procedure with only 5-25% of new oncology drugs in clinical development actually reaching the market mainly due ...
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