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Development of sensitive methodologies for exploitation of early epigenetic marker diagnosis in major types of cancer (EpiDiaCan)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2012,
Cancer is one of the major causes of mortality. Epithelial cells become malignant after accumulating genetic mutations followed by morphological changes in the epithelium. DNA Alterations include stable genetic changes in oncogenes, tumor suppressor genes and reversible epigenetic changes. Different forms of epigenetic mechanisms have been shown to modify the expression of key genes during tumour ...
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