4 projets européens trouvés
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TERMINÉ
Combatting Bacterial Resistance in Europe (COMBACTE-NET)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2019,
The emergence of Antibiotic-resistant bacteria (ARB) is a global problem, having recently been elevated to the top three threats identified by the World Health Organisation (WHO), and subject of numerous national and international government activities, including the Trans-Atlantic Task Force on Antimicrobial Resistance established by the US and EU presidencies. The estimated costs of ARB are aro ...
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38
Participants partenaires
TERMINÉ
PAtients Leading and mANaging their healThcare through EHealth (PALANTE)
Date du début: 1 févr. 2012, Date de fin: 31 juil. 2015,
Patient empowerment is considered a potential tool to reduce healthcare costs and improve efficiency of the health systems, reinforcing healthcare quality. Patient empowerment has become an element of high priority in the EU health strategy, supported by national and regional health authorities.Building on already existing e-health platforms and services in the participating regions, the PALANTE p ...
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21
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TERMINÉ
LINE-1 ACTIVITY IN SOMATIC STEM CELLS: IMPACT AND GENOMIC MOSAICISM (SOMATIC LINE-1)
Date du début: 24 juin 2008, Date de fin: 23 juin 2012,
"45% of the human genome is made of repeated DNA, and some types can be mobilized within the genome (mobile DNA). LINE-1 or L1 is the only autonomous active mobile DNA within the human genome, with 500.000 copies per haploid genome (~17% of the genome). Overall, L1 is responsible for ~30% of our genome. Due to its activity and number in the genome, the impact that L1 has and have on the genome is ...
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1
Participant partenaire
TERMINÉ
Developmental Impact of MLL-AF4 Fusion Gene linked to Infant Acute Lymphoblastic Leukaemia on Human Stem Cell Fate (Leukaemogenesis)
Date de fin: 1 sept. 2009,
The MLL gene is located in chromosome 11q23 and is implicated in >40 different chromosomal translocations, generating distinct leukaemic fusion genes. Unlike other MLL fusion proteins, t(4;11) MLL-AF4 is always found in infant pro-B-ALL with a dismal prognosis in infants and adults. In infant ALL where t(4;11) MLL-AF4 is very common (>80%), the gene fusion arises in utero. However, very litt ...
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