6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
European multicentre, randomised, phase III clinical trial of hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke (EuroHYP-1)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,
The consortium led by UKER and EuroHYP, the European Stroke Research Network for Hypothermia, proposes a large, multicentre clinical trial which will assess mild hypothermia as a novel treatment for ischemic stroke.Stroke is the second cause of death world-wide and the second cause of lost disability-adjusted life years in high-income countries. Stroke incidence rises exponentially with age, so it ...
Voir le projet
38
Participants partenaires
TERMINÉ
Ovarian Cancer Therapy – Innovative Models Prolong Survival (OCTIPS)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
"About 75% of advanced epithelial ovarian cancer (EOC) patients respond to first-line surgery and chemotherapy but most relapse and ultimately acquire platinum resistance which soon leads to death. Relapsed high grade serous ovarian cancer (HGSOC) is the single main cause of EOC-related morbidity and mortality (despite the fact that HGSOC is highly chemosensitive). We hypothesize that the primary ...
Voir le projet
11
Participants partenaires
TERMINÉ
bioMARkers and molecular tumor classification for non-genotoxic CARcinogenesis (MARCAR)
Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,
MARCAR aims to establish reliable early markers and molecular classification of tumors in non genotoxic carcinogenesis, applying a mechanism-based approach. Benefits are improved drug safety, more efficient drug development, and progress with 3 R issues. MARCAR focuses on rodent liver, the major target organ of non-genotoxic carcinogens (NGC). However, this approach will facilitate predictions for ...
Voir le projet
12
Participants partenaires
TERMINÉ
“The International Data Coordination Centre” (I-DCC)
Date du début: 1 janv. 2009, Date de fin: 30 sept. 2013,
"The I-DCC coordination and support project responds to the topic defined by HEALTH-2007-2.1.2-6 “International activities in large-scale data gathering and systems biology”. I-DCC integrates European skills, efforts, resources, and infrastructure in an international collaborative programme to establish a European Data Coordination Centre for mouse genetic resources. Large-scale mouse mutagenesis ...
Voir le projet
10
Participants partenaires
TERMINÉ
Genomic Regulatory Systems of Human X-linked neurological diseases (NeuroXsys)
Date du début: 1 juin 2009, Date de fin: 30 nov. 2012,
NeuroXsys will generate regulatory maps and models of the human X chromosome based on evolutionary conservation, with special attention to genes and regions implicated in X-linked neurological diseases. Vertebrate chromosomes are subdivided into domains of genomic regulatory blocks (GRBs) and NeuroXsys aims to map all GRBs on the X chromosome through bioinformatic approaches, extract gene regulato ...
Voir le projet
9
Participants partenaires
TERMINÉ
Sustaining access to Tissues and data frOm Radiobiological Experiments (STORE)
Date du début: 1 avr. 2009, Date de fin: 30 sept. 2012,
The sharing of data and biomaterials from publicly funded experimental radiation science adds enormous value to the original investment. Sharing will yield substantial scientific rewards through re-analysis and new investigations. The goal of STORE is to generate a platform that will allow the storage and retrieval of both data and the corresponding biological material from past, current and futur ...
Voir le projet