2 projets européens trouvés
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TERMINÉ
NOX enzymes as mediators of inflammation-triggered neurodegeneration: modulating NOX enzymes as novel therapies (NEURINOX)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,
NEURINOX aims at elucidating the role of NADPH oxidases (NOX) in neuroinflammation and its progression to neurodegenerative diseases (ND), as well as evaluating the potential of novel ND therapeutics approaches targeting NOX activity. NOX generate reactive oxygen species (ROS) and have emerged as regulators of neuroinflammation. Their role is complex: ROS generated by NOX lead to tissue damage in ...
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15
Participants partenaires
TERMINÉ
Gene- Environment Interactions in Heart Development (CHeartED)
Date du début: 1 janv. 2009, Date de fin: 31 déc. 2012,
Cardiovascular malformation (CVM) is the commonest cause of childhood death in developed countries. In the EU there are 51,000 new cases each year and two million affected individuals. Yet, despite intensive research, the cause of 80% of CVM remains elusive. The mission of CHeartED is to identify genetic and environmental pathways that can be modified with the goal of reducing preventable CVM inci ...
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