8 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Paediatric Clinical Research Infrastructure Network (PedCRIN)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Children’s health is a major societal challenge for Europe and the world, requiring development of paediatric medicines and treatments strategies based on evidence derived from clinical trials demonstrating efficacy and safety in infants and children, rather than on uncritical extrapolation from adult data (over 50 % of the medicines used for children had not been tested in this specific age group ...
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16
Participants partenaires
TERMINÉ
Comorbidity and Synapse Biology in Clinically Overlapping Psychiatric Disorders (COSYN)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
COSYN integrates outstanding European academic and three large Pharma to exploit genomic findings for intellectual disability (ID), autism, and schizophrenia. We capitalise on comorbidity, from clinic to cells and synapses, and have access to large existing samples. We focus on rare genetic variants of strong effect in patients with clinical comorbidity. Our aims are: (1) Understand comorbidity by ...
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14
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TERMINÉ
Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit (CloSed)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,
The majority of critically ill children admitted to Paediatric Intensive Care Units (PICU) will require sedation and analgesia which is commonly achieved with a combination of an benzodiazepine and an opioid. However, these agents have a significant side-effect profile, including tolerance, withdrawal and respiratory/circulatory depression. Clonidine is commonly used for sedation in PICU and recom ...
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10
Participants partenaires
TERMINÉ
European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,
ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients. Servicing multinational trials started during its preparatory phase, and it now applies for an ERIC status by 2011. The ERIC budget will be restricted to core activities re ...
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48
Participants partenaires
TERMINÉ
Advances in Small Trials dEsign for Regulatory Innovation and eXcellence (ASTERIX)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
"ASTERIX will contribute towards the expected impact listed in the work program by delivering validated innovative statistical design methodologies for cost efficient clinical trials deriving reliable results from trials in small population groups, especially focusing on rare diseases. It directly addresses the rights of the estimated 30 million European patients suffering from rare diseases to th ...
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7
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TERMINÉ
Global Research in Paediatrics (GRiP)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2017,
Paediatric drugs (PD) lack appropriate testing. Most drugs have inadequate information about dosing regimen, dose adjustment and how to administer them. These are longstanding problems that unquestionably require concerted efforts at the international level. Both the US and the EU have introduced paediatric legislation that facilitates participation of children in research and pharmaceutical innov ...
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24
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TERMINÉ
Genetic and Epigenetic Networks in Cognitive Dysfunction (GENCODYS)
Date du début: 1 mai 2010, Date de fin: 30 avr. 2015,
Mutations in about 400 different genes have been associated with Cognitive Disorders (CD), such as mental retardation, autism, neurodegenerative disorders, and psychiatric disorders. Whereas CD impose a major medical and socio-economical problem, there are no systematic studies that aim to provide insight into common mechanisms in CD. We propose a systems biology approach to gain insight into comm ...
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15
Participants partenaires
TERMINÉ
Identifying the Needs for Patients Partnering in Clinical Research (PatientPartner)
Date du début: 1 mai 2008, Date de fin: 30 avr. 2011,
The aim of this 3-year Coordination Action will be to identify the patients’ needs for partnership in the clinical trials context. Moreover, this project will lead to both a well-organized and sustainable communication platform and guidelines to enable the mutual beneficial interactions between patients and clinical trials professionals. This aim will be realized through: I) Interviews, addressing ...
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