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"Sudden cardiac death (SCD) following ventricular fibrillation (VF) is a major cause of mortality in the industrialised world. VF is characterised by chaotic electrical activity in the ventricles leading to severe cardiac dysfunction. Thus far, the underlying mechanisms for the initiation and maintenance of VF are not fully understood. Recent clinical developments in the treatment of VF by the Hos ...

Bone diseases like osteoporosis and osteoarthritis are affecting an increasing number of people worldwide. The short- and long-term consequences are an increasing risk of fractures, total joint replacement and bone grafting. Current treatments of osteoporosis are based on inhibition of bone resorption and at best preserve bone volume but do not improve bone formation together with a high risk of c ...