6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Long-term, prospective study evaluating clinical and molecular biomarkers of epileptogenesis in a genetic model of epilepsy – tuberous sclerosis complex (EPISTOP)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Despite a great progress in the management of epilepsy, still one third of patients is refractory to available medications. The incidence of epilepsy is highest in infancy and 50% of children experience epilepsy-related comorbidities, such as developmental delay and autism. The development of epilepsy (epileptogenesis), extensively studied in animals, is barely studied in humans, as patients usual ...
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16
Participants partenaires
TERMINÉ
Fishing for Medicines and their targets using Zebrafish models of human diseases (FISHMED)
Date du début: 1 déc. 2012, Date de fin: 31 mai 2016,
The International Institute of Molecular and Cell Biology (IIMCB) was created with the support of UNESCO, Polish Academy of Sciences (PAN) and the Polish Government and started its activity in 1999. The Institute is a unique, innovative, based on the best world standards research centre, known for it’s scientific excellence. In 2010, IIMCB was ranked first among 36 biological institutions in Polan ...
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1
Participant partenaire
TERMINÉ
STRENGTHENING COOPERATION IN MOLECULAR BIOMEDICINE BETWEEN EU AND UKRAINE (COMBIOM)
Date du début: 1 déc. 2011, Date de fin: 31 mai 2015,
True European leadership at the emerging frontiers of biomedical sciences could be achieved more effectively with participation of the most prominent scientists from the ENP countries. Ukraine is a country of high potential for scientific and technological development. Institute of Molecular Biology and Genetics is one of the leading scientific centres in molecular biomedicine area in Ukraine, whi ...
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3
Participants partenaires
TERMINÉ
Structural Biology of Membrane Proteins (SBMPs)
Date du début: 1 sept. 2008, Date de fin: 31 août 2012,
Membrane proteins (MPs) are known to be key molecules in cellular communications, from signal transduction to transport of ions, metabolites and other molecules. They also participate in the synthesis of ATP, the import of soluble or MPs from the cytosol, and they protect living organisms from toxic factors. The proposal consists in a joint training effort involving the major biophysical methods t ...
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12
Participants partenaires
TERMINÉ
Proteins in Health and Disease (HEALTH-PROT)
Date du début: 1 avr. 2009, Date de fin: 31 mars 2012,
This project is targeted at continuation and expansion of activities initiated as the FP5 Centre of Excellence in Molecular Bio-Medicine (CEMBM). In the past as the Centre of Excellence we developed an advanced methodology of analysis of complex protein structures with the use of cell and molecular biology techniques, biochemical methods, crystallographic analysis and computer modelling. Our goal ...
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1
Participant partenaire
TERMINÉ
GSK-3 in neuronal plasticity and neurodegeneration: basic mechanisms and pre-clinical assessment (NEURO.GSK3)
Date du début: 1 oct. 2008, Date de fin: 31 déc. 2011,
"Neuronal circuits in mammalian brain act predominantly via excitatory synapses on dendritic spines. Formation of new spines in adult brain constitutes the structural basis of neuronal plasticity. The underlying molecular mechanisms remain largely unknown but depend essentially on kinase-dependent signalling pathways. Final formation of synapses on spines depends on dynamic interactions of microtu ...
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