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Anti-Parasitic Drug Discovery in Epigenetics (A-PARADDISE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,
This proposal builds on the proven methodology developed in the SEtTReND FP7 project to develop inhibitors of schistosome HME as lead compounds for new drugs. We will employ a target-based strategy for the development of novel drug leads against schistosomiasis, leishmaniasis, Chagas disease and malaria by targeting histone modifying enzymes (HME), in particular those involved in acetylation/deace ...
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